Oana Gheorghe-Fronea's research while affiliated with University of Medicine and Pharmacy "Carol Davila" and other places

Publications (14)

Article
OBJECTIVE Diabetes prevalence is increasing rapidly in rural areas of low- and middle-income countries (LMICs), but there are limited data on the performance of health systems in delivering equitable and effective care to rural populations. We therefore assessed rural-urban differences in diabetes care and control in LMICs. RESEARCH DESIGN AND MET...
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Background: The aim of this study was to explore the rare variants in a cohort of Romanian index cases with hypertrophic cardiomyopathy (HCM). Methods: Forty-five unrelated probands with HCM were screened by targeted next generation sequencing (NGS) of 47 core and emerging genes connected with HCM. Results: We identified 95 variants with allel...
Article
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Peripheral arterial disease is associated with very high cardiovascular risk. The main symptom is intermittent claudication, which strongly affects the quality of life. Therefore, treatment goals in peripheral arterial disease consist of the reduction of cardiovascular events and the relief of symptoms. An increase in pain-free walking distance, ev...
Article
Purpose To evaluate the prevalence of atherosclerotic coronary lesions in young patients from a very high CV risk country, presented with a first ACS episode and to analyse the association between arterial stiffness, arterial age and the severity of CAD. Methods Sixty consecutive patients with age ≤45 years (mean age 41,25±3.99 years; range 22–45...
Article
Background: The relationship between insulin resistance and hypertension is well established, but the association of different surrogate insulin resistance indexes with the presence of hypertension is still under debate. The aim of this study was to compare the strength of the association between the presence of hypertension and six indexes: trigly...
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One of the challenges faced when conducting a clinical trial is the recruitment of the proposed number of participants. Accordingly, identifying barriers to patients' enrollment and developing effective strategies to overcome them is mandatory. One of the main strategies employed to improve participation rate consists of designing the informed cons...
Chapter
Hypertensive crisis can trigger the onset of an acute heart failure (AHF) episode through the steep increase in afterload that occurs as a result of the increase in blood pressure (BP) levels per se, through acute dissection of the ascending aorta, which can involve the aortic valve, leading to acute aortic regurgitation, and through an acute coron...
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Purpose of Review The aim of the paper is to test the influence of social status and psychological well-being (independent variables) on hypertensive condition (dependent variable), when adjusting for traditional risk factors of cardiovascular disease (control variables). The analysis is based on data collected from SEPHAR III, a nationally represe...

Citations

... The current study presents postoperative clinical and echocardiographic data from 83 consecutive patients with HCM and LVOT obstruction who underwent septal myectomy and MV repair in the Cardiomyopathy Center of Bucharest Monza Hospital. Patients' demographic data were comparable with statistics reported by Romanian Registry of Hypertrophic Cardiomyopathy [9] or other cohorts of Romanian patients with HCM [10], with a mean age falling in the sixth decade of life, and with male predominance. Baseline clinical characteristics and echocardiography findings were similar with those ...
... Although Sulodexide does not have a direct action on blood circulation, cardiac ejection fraction, blood pressure, or peripheral resistance, in patients with chronic venous disease, Sulodexide improves various parameters of venous hemodynamics (39)(40)(41). Clinical improvement with the use of Sulodexide has been repeatedly demonstrated in occlusive atherosclerosis of the lower limbs in observational, prospective, double-blind, randomized, multicenter, placebo-controlled trials (42)(43)(44)(45)(46)(47)(48). Sulodexide-induced positive hemorrheological changes are likely due to improvement of venous and arterial circulation. ...
... Although several studies have demonstrated that these novel lipid-related obesity indicators were positively associated with hypertension [6], there are no data on their association with ISH and whether they have an advantage over traditional indicators. Thus, we conducted this large-scale cross-sectional study to compare the association of traditional and lipid-related obesity indicators with ISH. ...
... When the material needs became a problem, the spiritual needs were no longer pursued [30]. Economic status also influenced physical and psychological conditions [31]. Thus, the importance of economic status for older adults and as a factor affecting their dignity was confirmed [32]. ...