O A Mel'nyk’s scientific contributions

A comparative investigation was conducted of several methods for measuring the activity of the diphterial antitoxin in the preparation of allogenic antidiphterial immunoglobulin. The results of the studies made allow recommending the flocculation reaction and statistical method for use at blood transfusion stations in Ukraine when manufacturing the antidiphterial immunoglobulin, due to their informative, economic value and because they can easily be performed.

Antidiphtheritic antibodies were studied in the blood serum of Kiev and Kiev region population capable of blood donation (984 persons). It has been found out that antidiphtheritic antibodies were present in men's and women's blood serum of different blood groups (by ABO system) during a year. Antidiphtheritic antibodies with high titers > 1.80 were most often found in autumn, winter and spring in people having A (II), B (III) and AB (IV) blood groups.