Noh Ga-Yeong’s scientific contributions

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Publications (1)


Therapeutic Effects of Atobeauty Cream in Atopic Dermatitis Model Mice Induced with DNCB
  • Article

February 2012

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47 Reads

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3 Citations

Research Journal of Medical Sciences

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Park Sang-Oh

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Ahn Yong-Sik

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[...]

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Noh Ga-Yeong

This study has been performed to assess the anti-atopic efficiency in DNCB induced BALB/c to examine a therapeutic effect of Atobeauty cream which was provided by NJY Life Science Co., Ltd. on atopic dermatitis. Such BALB/c mice were provided by NJY Life Science Co., Ltd. The randomized complete block design was done by dividing 20 male mice with BALB/c into two groups of which the one group had 10 mice receiving no treatment as a control group and the other group had 10 mice receiving treatment with Atobeauty cream as a treatment group. When Atobeauty cream was applied to the mouse with severe atopic dermatitis 2 times a day for 6 days, it could be observed that its skin recovered to normal condition with the skin surface being clean and smooth without any horny tissue. It was found that each level of IgE and histamine in blood was significantly decreased by 57.80 and 59.41%, respectively in the Atobeauty cream treatment group (here in after, the treatment group), compared with the DNCB induced atopy control group (here in after, the control group (p<0.05). It was also identified that a mouse with atopic dermatitis to which Atobeauty cream was applied, recovered on the order of a normal mouse as its epidermis got to be softly formed with its surface thickness being even and its connective tissue got to be formed more uniformly.

Citations (1)


... Atopic dermatitis is related to an increased risk of various complications including food allergy, asthma, allergic rhinitis and mental health disorders. According to the pathological physiology, it is known to accompany a complicated and strong genetic predisposition, epidermis dysfunction and T cell inflammation (Park et al., 2012;Torres et al., 2019;Langan et al., 2020). Atopic dermatitis animal biomodels can be produced by applying DNCB (dinitrochlorobenzen e), DNFB (dinitrofluorobenzene), Oxazolone to Nc/Nga, Flaky tail and BALB/c mice for a preclinical trials regarding atopic dermatitis (Kohara et al., 2001;Martel et al., 2017), To produce an atopic dermatitis animal biomo del, all hair was removed from the back of a BALB/c mouse from the bottom of its ear to the top of its tail and the rat was left alone for 24 hours. ...

Reference:

CONVERGENCE STRATEGY OF DIGITAL LIVESTOCK PRODUCTION AND ANIMAL BIOMODELS FOR HUMAN WELLNESS IN FUTURE: A REVIEW
Therapeutic Effects of Atobeauty Cream in Atopic Dermatitis Model Mice Induced with DNCB
  • Citing Article
  • February 2012

Research Journal of Medical Sciences