Niklas Vogt's research while affiliated with University of Wuerzburg and other places

Publications (2)

Article
Full-text available
Background In severe cases, SARS-CoV-2 infection leads to acute respiratory distress syndrome (ARDS), often treated by extracorporeal membrane oxygenation (ECMO). During ECMO therapy, anticoagulation is crucial to prevent device-associated thrombosis and device failure, however, it is associated with bleeding complications. In COVID-19, additional...
Article
Full-text available
Background Autopsies are an important tool in medicine, dissecting disease pathophysiology and causes of death. In COVID-19, autopsies revealed e.g., the effects on pulmonary (micro)vasculature or the nervous system, systemic viral spread, or the interplay with the immune system. To facilitate multicentre autopsy-based studies and provide a central...

Citations

... The bleeding complications of ECMO are usually related to anticoagulation and include gastrointestinal bleeding, craniocerebral hemorrhage, and airway hemorrhage. In COVID-19, in ammation, vascular endothelial injury, and coagulation disorders lead to the coexistence of thrombosis and bleeding risk; if anticoagulation is used in COVID-19 treatment, the bleeding risk may further increase [11,12]. Studies have shown that the incidence of major bleeding in patients with COVID-19 treated with ECMO is 30.9-42% ...
... Low rates of fatal courses might also influence the correctness of national statistics. The establishment of model regions with monitoring of the ongoing pandemic with autopsies at high frequency to be embedded in a registry such as the German COVID-19 autopsy registry [40] , could be an appropriate approach to gain insight rapidly into an ongoing pandemic. ...