Nikita Shinde’s scientific contributions

When applied across the skin's mucous membrane, skin care products including gel, lotion, ointment, cream, peel-off masks, etc., are meant to have a localised effect. A peel-off mask is a type of dosage form that is gently placed to the face and taken off after a short while. It is said to tighten, moisturise, and eliminate tan lines from the skin in addition to treating common skin problems. We are now preparing the recipe for a Tulsi peel-off face mask. Tulsi extract lessens acne, evens out skin tone, and slows down the ageing process of the skin. As excipients, the formulation includes glycerol, citric acid, and polyvinyl alcohol (PVA) etc. Numerous formulations were examined for peeling time, spreadability, pH, and stability studies, among other attributes. When evaluated for the parameters, the formulation is found to be within the designated range.

The oral route is the most common route of drug delivery, but the administration of drugs through the oral routeshows a few disadvantages, like first-passmetabolism, drug degradation in the gastrointestinal tract due to enzymes and pH of the stomach, GI irritation, low bioavailability, etc. To overcome this problems, the Transdermal Drug Delivery System (TDDS) was developed. Transdermal Drug Delivery Systems, also known as "Patches" are the painless way of systemically administering therapeutically active medication by placing a drug formulation on intact and healthy skin. Skin is an effective medium through which absorption of the drug takes place and entersin the blood stream overthe period of time. Different types of transdermal drug delivery systemsare developed, which demonstrate different release kinetics. This review article provides a detailed study of TDDS advantages, disadvantages, drug permeation pathways, types of transdermal drug delivery systems and their components, factors affecting the formulation of TDDS, and their evaluation parameters. The review also contains future prospects for transdermal drug delivery systems.