Neelam Sayed's research while affiliated with Ramnarain Ruia College and other places

Publications (12)

Article
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The leaf bud of Ficus benghalensis L. (Moraceae) is commonly known as Vatankur. It is traditionally used in the treatment of diarrhoea, skin disorders, female reproductive disorders and as a hair vitalizer. In the present study macroscopic, microscopic, proximate, phytochemical and safety profile of Vatankur has been evaluated and discussed. Findin...
Article
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The aim of the current study was to evaluate pharmacognostic characters of leaves of Parkia biglandulosa Wight & Arn. The evaluation was carried out in terms of macroscopic, microscopic, physicochemical, phytochemical and chromatographic analysis.Leaves of P. biglandulosa showed the presence of circular dark brown gland at its base on either side o...
Article
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Carissa carandas Linn. is an evergreen, diffuse and spiny shrub grown in different parts of India for its edible fruits. Fruits of C. carandas are used as potential analgesic, anti-inflammatory and anti-diabetic agent. An HPTLC method has been developed and validated for estimation of β-sitosterol content in C. carandas fruits collected from differ...
Article
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Background: Seeds of Asteracantha longifolia Nees. (Acanthaceae) are an important ingredient in many traditional/herbal formulations used in the management of a wide range of reproductive disorders. They are reported to posses various therapeutically active phytochemical constituents like asteracanthine, lupeol, asterol, β-sitosterol etc. Materials...
Article
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The present work is an attempt to evaluate the impact of regional variation on lupeol content in Carissa carandas Linn. fruits collected from different geographical regions of India using a validated HPTLC method. Chromatographic separation was achieved on TLC plates pre-coated with silica gel 60 F 254 using toluene: methanol (8:1, v/v) as a mobile...
Article
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Background: Psoralea corylifolia L. (Fabaceae, seeds) is used in many formulations for the treatment of a wide range of ailments. Aims and Objective: To develop a reverse phase high-performance liquid chromatography-photodiode array detector (RP-HPLC-DAD) method for quantitation of psoralen from P. corylifolia and its related formulations. Material...
Article
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Background : Carissa carandas L. (Apocynaceae), an important fruit of tropical and subtropical arid region, has a great potential for the development of a new phytotherapeutic medicine. Due to an increase in commercial products of this fruit in the global market, an extensive phytochemical comparison seems imperative to understand its internal qual...
Article
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Sufoof -e -Ziabetes -Dulabi (SZD) is an Unani formulation, used for diabetes and renal disorders since ancient times. In the present work, quality of the raw material and the final product SZD was assessed by modern bioanalytical techniques. Quality of the ingredients of SZD was evaluated prior to its preparation. Values of proximate analysis for t...
Article
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Jawarish-e-Bisbasa, an Unani polyherbal formulation, is used traditionally in the clinical treatment of stomach ulcers, weakness of digestion, piles, flatulence, nausea, gastritis and as an energy enhancer for stomach. In the current work; phytochemical, safety and pharmacokinetic profile of Jawarish-e-Bisbasa has been evaluated. Phytochemical cons...
Article
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Trigonella foenum-graecum (L.) (Fabaceae, Fenugreek) is an important ingredient of Ayurvedic and other marketed herbal formulations. Fenugreek seeds are employed in many traditional systems as an antibacterial and antidiabetic agent, gastric stimulant and galactogogue. Trigonelline, a major phytoconstituent found in fenugreek seeds, shows estrogeni...
Article
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Trikatu Churna (TC) is an ancient traditional Ayurvedic preparation prescribed for a wide range of disorders. Though TC is an age old formulation, there are very few references on its quality control and standardization. In this work, an attempt has been made to standardize TC by qualitatively evaluating the preliminary phytochemicals. Piperine con...

Citations

... The present work is focused to develop method for standardization of Aegle marmelos (bael) fruit pulp used in many herbal preparations, on the basis of marmelosin -a major chemical constituent present [4,5]. ...
... All parts of Cordia obliqua Willd was evaluated for pharmacognostic studies 5 ,but detailed study was lacking on the bark. Pharmacognosy, in recent years has gained immense importance as it is an efficient tool for the authentication and identification of plant raw materials and therefore evaluation of pharmacognostic parameters is an indispensible step when dealing with herbal drugs 6 . Due to the medicinal importance of C. obliqua, a complete study on macroscopic, microscopic characters and analytical parameters of stem bark has been made. ...
... Wahab (2013) analyzed physico-chemical and pharmacognostical properties for Averrhoa carambola. Shailajan et al. (2014) worked on the leaf bud of Ficus benghalensis L. Sonkar et al. (2014) carried out morphological investigation on leaves of Momordica dioica Roxb. These studies confirm that pharmacognostic investigation of crude drug is chief requisite for identification and authentification, determining quality and purity of drugs. ...
... In line with these facts, in this research work five different Dendrobium species namely; D. nobile, D. fimbriatum, D. moschatum, D. chrysanthum and D. chrysotoxum were evaluated for their ursolic acid, β-sitosterol and lupeol (terpenoids) and gallic acid (a phenolic compound) content using validated HPTLC techniques. Based on the reported therapeutic activities of ursolic acid (Kaewthawee and Brimson, 2013), β-sitosterol (Saeidnia et al., 2014;Shailajan et al., 2013), lupeol (Gallo and Sarachine, 2009) and gallic acid (Harish et al., 2008) they were selected as markers for phytochemical characterization of various Dendrobium species. ...
... After complete evaporation of the methanol by rotary evaporator, the methanol-soluble extracts were dissolved in 1 mL methanol. The samples after filtering were used for determination of trigonelline by HPLC [21] . The HPLC system equipped with a reverse-phase C18 column (OSD-UG-5, 4.6 mm × 250 mm × 10 μm) and UV detector. ...
... There is no unique in regard to that analytical marker content in these herbal products. Concerning the investigation of the content of chemical marker in medicinal plants, there are many controlled factors that affect the production of naturally bioactive compounds such as the difference of plant habitats, the suitable season for the medicinal harvest and the environment of crops (Jayanthy et al., 2013;Shailajan et al., 2013). Thus, in-depth studies on the variation of contents of selected compound relating those of regulating factors are essential for establishing the standard specifications of the herbal remedy. ...
... Dahikar et al. [3], Malvankar and Abhyankar [4] studied the in vitro antibacterial potential of Trikatu churna and its ingredients. Sunita et al. [5] studied the standardization of Trikatu churna using bioanalytical tools. The preliminary phytochemical screening showed the presence of alkaloids, tannins and essential oils, flavonoids, glycosides, and resins. ...
... Although, there are several ayurvedic formulations of BO in Indian market, however, psoralen has not been assessed from traditional commercial preparations. In addition, pharmacokinetics of any traditional preparation has not been reported in the literature using psoralen (Shailajan et al. 2012). Besides this, BO suffers from instabilities resulting from oxygen, temperature, and light that can lead to its oxidation and degradation. ...
... [25,26] Several previous studies have reported the validation of chromatographic methods for lupeol content analysis. [29][30][31][32][33][34][35][36][37][38] For example, the lupeol content in Vernonanthura ferruginea was determined by HPLC using a C8 reverse-phase column, with acetonitrile: acetic acid (99.99:0.01, v/v) as the mobile phase at a flow rate of 0.8 mL/min. ...
... [97] However, there are PIPs marketed in the form of ayurvedic formulation: Habb-e-Khardel. [98] Eladi Gutika, [99] Jawarishe-Bisbasa, [100] Trikatu Churna, [101] LasunadiVati, Marichyadivati and Kaphaketu rasa. [102] Drug delivery systems One of the limitations of PIP is its low solubility in water, causing limitation in clinical application. ...