Naveen Chandrashekar's research while affiliated with University of Waterloo and other places
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Publications (54)
Purpose
The purpose of this study was to investigate biomechanical differences of medial patellofemoral ligament (MPFL) reconstruction, medial quadriceps tendon femoral ligament (MQTFL) reconstruction and a combination of these techniques to restore lateral patellar constraint and contact pressures.
Methods
Eight fresh frozen cadaver knees were mo...
Carpal tunnel syndrome and tendonitis are two common upper extremity cumulative trauma disorders (CTD) related to repetitive and forceful activities in industrial environments. Reducing the muscular force during activities such as the operation of a pistol grip hand tool could result in lower incidence of CTDs. The objective of this research was to...
Objectives:
Grip force during hand tool operation is the primary contributor to tendon strain and related wrist injuries, whereas push force is a contributor to shoulder injuries. However, both cannot be directly measured using a single measurement instrument. The objective of this research was to develop and test an algorithm to isolate the grip...
Accidental foot injuries including metatarsal fractures commonly result from compressive loading. The ability of personal protective equipment to prevent these traumatic injuries depends on the understanding of metatarsal fracture tolerance. However, the in-situ fracture tolerance of the metatarsals under direct compressive loading to the foot's do...
Purpose: Tendonitis and carpal tunnel syndrome are common cumulative trauma disorders that can occur with repetitive usage of pistol grip power tools. The role of reaction torque resulting in a forceful rotary displacement of the tool handle, as well as the role of applied grip force, is not clear in the development of these disorders. The purpose...
Background: Meniscal strain patterns are not well understood during dynamic activities. Furthermore, the impact of ACL reconstruction on meniscal strain has not been thoroughly investigated. The purpose of this study was to characterize ACL and meniscal strain during dynamic activities and investigate the strain difference between ACL-intact and AC...
Mechanical stimulation and fluid perfusion during in vitro conditioning have the potential to improve constructs for clinical applications in the focal defect repair of load-bearing articular cartilage tissue. The present study uses a novel stimulator with a sliding “elastohydrostatic-type” bearing contact to exert a combination of loads and perfus...
Background:
A medial meniscal tear is a common knee injury, especially following an anterior cruciate ligament injury. Decreasing the compressive force on the medial meniscus during dynamic activities using an unloader knee brace could reduce meniscal strain, effectively reducing injury risk and/or severity.
Objectives:
To investigate the effica...
Estimation of muscle forces through musculoskeletal simulation is important in understanding human movement and injury. Unmatched filter frequencies used to low-pass filter marker and force platform data can create artifacts during inverse dynamics analysis, but their effects on muscle force calculations are unknown. The objective of this study was...
Purpose:
The effectiveness of ACL functional knee braces to reduce meniscal and ACL strain after ACL injury or reconstruction is not well understood. A new dynamic knee tensioning brace system has been designed to apply an active stabilizing force to the knee. The ability of this system to reduce tissue strains is unknown. The purpose of this stud...
Unloader knee braces are prescribed for patients with unicompartmental osteoarthritis of the knee. These braces aim to reduce pain in patients by applying a coronal moment to the knee to unload the symptomatic knee compartment. However, existing unloading mechanisms use straps that go directly behind the knee joint, to apply the needed moment. This...
We thank the authors of the letter (1) for their comments regarding our paper "Effect of Sagittal Plane Mechanics on ACL Strain during Jump Landing"(2) . Breaking apart the fundamental influencers of ACL strain and injury is difficult, in part due to the multitude of variables involved. Research studying these interconnected variables increases the...
The relationships between non-contact anterior cruciate ligament injuries and the underlying biomechanics are still unclear, despite large quantities of academic research. The purpose of this research was to study anterior cruciate ligament strain during jump landing by investigating its correlation with sagittal plane kinetic/kinematic parameters...
It is unknown whether prophylactic knee braces can reduce the strain in the anterior cruciate ligament during dynamic activities.
An athlete, who had characteristics of high anterior cruciate ligament injury risk, was chosen. A motion capture system (Optotrak Certus; Northern Digital, Waterloo, ON, Canada) was used to record dynamic trials during d...
Numerical finite element models of the neck have been developed to simulate occupant response and predict injury during motor vehicle collisions. However, there is a paucity of data on the response of young cervical spine segments under dynamic loading in flexion and extension, which is essential for the development or validation of Detailed Finite...
Craniovertebral ligaments were tested to failure under tensile loading. Ligaments tested included: transverse ligament, anterior atlanto occipital membrane, posterior atlanto occipital membrane, capsular ligaments between Skull-C1 and C1-C2, anterior atlantoaxial membrane, posterior atlantoaxial membrane and the tectorial membrane/vertical cruciate...
The mechanism of noncontact anterior cruciate ligament (ACL) injury is not well understood. It is partly because previous studies have been unable to relate dynamic knee muscle forces during sports activities such as landing from a jump to the strain in the ACL. We present a combined in vivo/in vitro method to relate the muscle group forces to ACL...
Mechanical stimulation is a key technique used for controlling the mechanical properties of tissue engineered articular cartilage constructs proposed for defect repair. The present study introduces a new technical method and device for 'hydromechanical' stimulation of tissue engineered articular cartilage constructs. The stimulation consists of sim...
Myopia is a refractive error of the eye and is characterized by an increase in the axial length of the eye. The exact mechanisms for the axial elongation are still unknown. Higher intraocular pressure (IOP) has been associated with myopia and could be involved in eye enlargement along with other factors. However, studying the creep behaviour of the...
Myopia is characterized by an increase in axial length of the eye, but the reasons for the axial elongation are still unknown. Higher intraocular pressure (IOP) has been associated with myopia and could be involved in eye enlargement. The purpose of this study was to investigate the effect of intraocular pressure on the geometry of the chick eye an...
The cervical spine ligaments play an essential role in limiting the physiological ranges of motion in the neck; however, traumatic loading such as that experienced in automotive crash scenarios can lead to ligament damage and result in neck injury. The development of detailed neck models to evaluate the response and the potential for injury require...
Anterior cruciate ligament (ACL) injury continues to be at the forefront of sports injury concerns because of its impact on quality of life and joint health prognosis. One strategy is to reduce the occurrence of this injury by identifying at-risk subjects based on key putative risk factors. The purpose of our study was to develop models that predic...
Bone-patellar tendon-bone (BPTB) graft is a popular choice for ACL reconstruction. These grafts are subjected to cyclic loading during the activities of daily living. Significant knee laxity is observed in reconstructed knee shortly after reconstruction. The source of this laxity is not clear. The change in the tensile properties of the graft due t...
The geometry of anatomical specimens is very complex and accurate 3D reconstruction is important for morphological studies, finite element analysis (FEA) and rapid prototyping. Although magnetic resonance imaging, computed tomography and laser scanners can be used for reconstructing biological structures, the cost of the equipment is fairly high an...
Traumatic knee injuries in automobile accidents and sports often lead to damage of the peroneal nerve. A lack of control of muscles innervated by the peroneal nerve due to this damage, results in the inability to dorsiflex and evert the foot and to extend the toes. This condition is commonly known as foot drop. Foot drop reduces the stability in th...
We hypothesize that application of an unopposed quadriceps force coupled with an impulsive ground reaction force may induce anterior cruciate ligament (ACL) injury. This situation is similar to landing from a jump if only the quadriceps muscle is active; an unlikely but presumably dangerous circumstance. The purpose of this study was to test our hy...
The geometry of the tibial plateau has been largely ignored as a source of possible risk factors for anterior cruciate ligament injury. Discovering the anterior cruciate ligament injury risk factors associated with the tibial plateau may lead to delineation of the existing sex-based disparity in anterior cruciate ligament injuries and help develop...
The geometry of the tibial plateau is complex and asymmetric. Previous research has characterized subject-to-subject differences in the tibial plateau geometry in the sagittal plane on the basis of a single parameter, the posterior slope. We hypothesized that (1) there are large subject-to-subject variations in terms of slopes, the depth of concavi...
Although the linear elastic (high-load) properties of patellar tendon graft used for anterior cruciate ligament (ACL) reconstruction are studied extensively, the low-load properties of the graft, associated with the toe region of its load-deformation curve, are largely neglected. The objectives of this study were to (i) determine the properties of...
The purpose of this study was to investigate the existence of sex-based differences in the ultrastructural characteristics of the human anterior cruciate ligament (ACL) as the underlying cause of differences in the structural and mechanical properties between sexes. The ACL of six male and six female cadaveric donors were randomly chosen from a poo...
In the United States, an estimated 100,000 anterior cruciate ligament (ACL) injuries occur every year. Despite decades of
research, to this date, the mechanism or mechanisms of non-contact ACL injuries are not well understood. This is primarily
because trials cannot be conducted on live subjects to understand the injury mechanism, and it is difficu...
This work is concerned with the 3D finite element modeling of porous implants in which the pore characteristics and distribution are taken into account. The analysis is conducted for scaffolds composed of various biocompatible materials such as Hydroxyapatite, PMMA, PEEK, Ti-6Al-4V, Silicon Nitride, Zirconia and Alumina. Furthermore, the potential...
After immense amounts of research, the root cause for the significantly higher rates of anterior cruciate ligament (ACL) failure incidents in females as compared to males still remains unknown and the existing sex-based disparity has not diminished. To date, the possibility that the female ACL is mechanically weaker than the male ACL has not been d...
An interactive Web-based experiment was designed as a preparation tool for students in the Materials and Mechanics Laboratory course at Texas Tech University. In the Web-based experiment, the students were given an introduction to the concept of hardness, what it means, how it is measured, and the calibration and utilization procedure using a Rockw...
Web based preparation of students in laboratory based courses may offer unique features and benefits over conventional in-class preparation. Apart from reduced costs and training time, it is an effective tool for education and preparation of large classes, convenient for students due unlimited access without time constraints, and more importantly,...
A significantly higher rate of anterior cruciate ligament injuries occurs in women involved in sports activities compared to the corresponding male population. Reasons for this disparity are not well understood; however, sex-based differences in the geometry of the anterior cruciate ligament, its morphologic characteristics, and the intercondylar n...
A diverse range of values for the mechanical properties of the human patellar tendon has been reported in the literature. Donor age has been excluded as a factor that causes this disparity. However, the effects of donor sex and tissue mass density on the mechanical properties of the patellar tendon have not been established. More importantly, predi...
Accurate and flexible measurements of length, area, and volume are important in evaluation of the mechanical properties of soft tissue. Although a number of contact-based and non-contact techniques have been reported in the literature, due to a variety of reasons such as cost, complexity, and low accuracy, the research community has not adopted a s...
An interactive web-based software on ‘Tensile Testing of Materials’ is developed to help undergraduate students learn more effectively about the objectives, procedure, and methods used in the experiment. The main objective was to better prepare the students in performing their tasks during the physical experiment. The intention of this project is t...
The development and evaluation of a realistic virtual materials science laboratory experiment on metallography is reported in this paper. This virtual laboratory is highly interactive and has been designed considering a number of learning styles. All standard laboratory functions such as stating the objectives of the experiment, background, procedu...
Recent research suggests that estradiol affects the material properties of the Anterior Cruciate Ligament (ACL). Here we experimentally determine the cross-sectional area and tensile properties of ACLs from the groups of prepubertal rabbits: untreated control (C ), estrogen treated (E ) and estrogen and epidermal growth factor treated (E+EGF). Estr...
An interactive web-based experiment was designed as a preparation tool for students in the Materials and Mechanics Laboratory course at Texas Tech University. In the web-based experiment, the students were given an introduction to the concept of hardness, what it means, how it is measured, and the calibration and utilization procedure using a Rockw...
Soft tissues in the cervical spine are known to exhibit strain rate dependent behaviour. The objective of this study is to test the hypothesis that the response of the cervical spine segment to loading in flexion and extension is also rate dependent. Eight cervical spines were sectioned into segments (four segments in total at each level from C2-C3...
Citations
... The sensors manufactured by Tekscan have been used in the studies on the pressures in the soil [3][4][5][6][7], railroad track pressure [8], pressure in the joints [9,10], pressure by medical pressure garments and socks [11][12][13], pressure when gripping tools and handles [14][15][16], pressures between rolling elements [17] and others. This variability of applications is The structure of the paper is as follows. ...
... They provide the interactivity feature that allows users to input data and receive responses from a simulation which changes dynamically as a result of changing input setting such as opening or closing of a valve in a pipeline. A large percentage of virtual labs reported in the literature belong to this category [19][20][21][22][23][24] , spanning practically every field of engineering. Immersive interactive virtual labs represent improvement over interactive virtual labs since they provide both interactivity as well as immersion, in three-dimensions. ...
... Prophylactic bracing has demonstrated reduced strain on the posterior horn of the medial meniscus in cadaveric models and has been studied in several populations with widely variable results. 91 In vivo, a medial unloader brace has demonstrated increased peak knee flexion moment and increased knee stability when performing single-leg squat, forward lunge and during ambulation. 30 In collegiate football players, prophylactic bracing compared with no brace significantly reduced medial collateral ligament (MCL) and meniscus injuries. ...
Reference: The Epidemiology of Meniscus Injury
... Analog force plate data collected in Simi Motion were exported to Visual3D software (C-Motion, Inc, Germantown, MD, USA). Analog force plate data were low-pass filtered at 12 Hz, using a fourth-order Butterworth filter [20]. ...
... Proprioceptive ACL knee braces are used for athletes seeking effective and timely RTS by influencing knee kinematics during dynamic activities following reconstruction, reducing the risk of recurrent ACL injuries 24 . Dynamically tensioned functional ACL braces have been reported to lower peak and average ACL and meniscal strain during walking and body-weight squatting 25 . Dynamic braces function by applying an active corrective force to the thigh with an opposing counterforce to the anterior aspect of the tibia, effectively reducing stress on the ACL graft (anti-Lachman forces) during ambulation. ...
... 13 Based on design and constructional criteria, knee braces can be categorized as single hinge-double hinge, hinge post strap-hinge post shell, polycentric hinge-monocentric hinge, off-the-shelfcustom-made, and elastic strapping-rigid strapping. 14 While experimental and computational study of the knee braces has been reported in several publications, 9,[15][16][17][18][19][20][21][22][23][24][25] there are still many aspects that require more investigation. In the current study, effects of increasing elastic strap tightening pressure and width, adding torsion spring, and applying brace pre-tension on the effectiveness of a bilateral single-hinged bracing for knee OA treatment were evaluated using the finite element (FE) method. ...
... This approach has been applied to material science laboratories [8,10] and experimental methodology [9]. Fully interactive virtual metallographic, and hardness measurement experiments with highly interactive decision tree structures have also been developed [8,11] to promote higherorder learning. ...
... The use of learning styles in engineering education has become fairly widespread. A search of the term "learning styles" in the ASEE conference proceedings from 2000 through 2006 turned up hundreds of articles covering a wide range of topics including the effects of learning styles on academic performance [4] and on retention [5] as well as on the design of technology-based learning tools [6]. Among the ASEE articles referring to learning styles are nearly 50 that use the Index of Learning Styles © (ILS) of Felder and Soloman [7]. ...
... Singleleg landing mechanics can help to understand the anticipated forces on the ACL, such as strain encountered from excessive frontal plane motion or limited and stiff sagittal plane motion. [11][12][13] Excessive frontal plane motion at the trunk and knee when landing have been linked to initial ACL injuries and reinjuries of the reconstructed ACL. [14][15][16][17] Stiff landing patterns with less peak knee flexion that place greater strain on the ACL 11,13 correlate to riskier frontal plane mechanics 18 and worse quadriceps strength, 19,20 and predict decreased function 21 and primary and secondary ACL injuries. ...
... Refractive surgery is used to improve the visual acuity of patients with common refractive illnesses. FEM has been used to analyze mechanical properties and corneal curvature before and after the refractive surgery [2][3][4][5][6][7][8][9]. Moreover, an FE model has been developed for simulating corneal tissue cutting by using boundary condition [10]. ...