Naveed Kazi's research while affiliated with Liaquat University of Medical and Health Sciences and other places

Publications (59)

Article
The determination of trace and toxic metals in the biological samples of human beings is an important clinical screening procedure. The aim of the present study was to compare the level of essential trace and toxic elements cadmium (Cd), calcium (Ca), lead (Pb), and magnesium (Mg) in biological samples (whole blood, urine, and scalp hair) of male p...
Article
Background: The abnormal metabolism of metal ions plays an important role in health and disease conditions, and studies about them have been attracting significant interest. The aim of our study was to assess the toxic elements arsenic (As), cadmium (Cd), nickel (Ni), and lead (Pb) in biological samples (scalp hair, blood, urine) of 387 hypertensi...
Article
Background: The consequence of trace elements deficiency has been associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) disease progression and mortality. This study examined the association between high concentrations of chromium (Cr) and manganese (Mn) in scalp hair, blood, and urine and opportunistic infections in hos...
Article
Full-text available
The abnormal metabolism of metal ions plays an important role in health and disease conditions, and studies about them have been attracting significant interest. The aim of our study was to assess the essential minerals (calcium (Ca), magnesium (Mg), potassium (K), and sodium (Na)) in biological samples (scalp hair, blood, urine) of 387 hypertensiv...
Article
The abnormal metabolism of metal ions plays an important role in health and disease conditions, and studies about them have been attracting significant interest. The aim of our study was to assess the trace metals (copper (Cu), iron (Fe), and zinc (Zn)) in biological samples (scalp hair, blood, urine) of 387 hypertensive males and females, age rang...
Article
Electrolyte deficiency has been associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) disease progression and mortality. This study examined the association between low electrolyte concentrations in blood and scalp hair and the presence of opportunistic infections in patients with acquired immune deficiency syndrome (AIDS...
Article
The aim of the present study was to compare the level of chromium (Cr), cobalt (Co), and manganese (Mn) in biological samples (blood, urine, and scalp hair) of patients suffering from different types of viral hepatitis (A, B, C, D, and E; n = 521) of both genders, ages ranging from 31 - 45 years. For comparative study, 255 age-matched control subje...
Article
Arthritis is a chronic inflammatory disease resulting in inflammation of diarthrodial joints (particularly joints of hands, wrists, feet, knees, ankles, and shoulders), manifested by swelling and functional impairment. This study was designed to evaluate the levels of the toxic elements arsenic (As), cadmium (Cd), and lead (Pb) and correlate those...
Article
The use of natural remedies and pharmacological mineral supplements for liver disease treatment has a long history. In present study, the levels of selenium (Se) and zinc (Zn) were determined in biological samples (serum and whole blood) of female hepatitis C patients (n = 132), age ranged 30-45 years, before and after 30 days treatment with herbal...
Article
Background: A great number of studies have investigated the possible role of trace elements in the etiology and pathogenesis of rheumatoid arthritis (RA). Methods: The aim of the study was to evaluate copper (Cu), iron (Fe), and zinc (Zn) levels in three biological samples (scalp hair, blood, and urine) in patients with rheumatoid arthritis (RA)...
Article
The aim of the present study was to compare the levels of essential trace and toxic elements in biological samples (blood and serum) of male liver cirrhotic/cancer patients (n = 144), of age groups 30-50 years, before and after 60 days treatment with mineral supplementation. For comparison purposes, the same biological samples were also collected f...
Article
Background & aims: The aim of present study was to compare the levels of essential trace and toxic elements in biological samples (blood, serum and scalp hair) of female liver cirrhotic/cancer patients (n = 132), of two age groups (20-45 years) and (46-60 years), before and after sixty days treatment with mineral supplementation. For comparison pu...
Article
Psoriasis is a noncontagious, chronic skin disease affecting 1 in 50 people worldwide. The aim of present study was to compare the levels of arsenic (As) and selenium (Se) in samples of whole blood, urine, and scalp hair of 418 psoriasis patients of both genders aged 25 - 55 years. All psoriatic patients lived in the vicinity of a cement factory, a...
Article
Rheumatoid Arthritis is a chronic inflammatory disease resulting in joint inflammation (particularly joints of hands, wrists, feet, knees, ankles, and shoulder) that is manifested by swelling and functional impairment. This study was designed to compare the levels of calcium (Ca), magnesium (mg), potassium (K), and sodium (Na) in four biological sa...
Article
Full-text available
Iodine deficiency affects a substantial portion of the world’s population, provoking severe health problems as well as important economic losses to the region in which this condition is found. In present study, evaluated the levels of urinary iodide (UI) and thyroid hormone status in female hypothyroid patients (HPs) and control subjects of same ag...
Article
Full-text available
This study was designed to compare the levels of chromium (Cr) and manganese (Mn) in scalp hair, blood, and urine of night blindness in children age ranged (3-7) and (8-12) years of both genders, comparing them to sex- and age-matched controls. A microwave-assisted wet acid digestion procedure, was developed as a sample pretreatment, for the determ...
Article
Full-text available
The most common cause of blindness in developing countries is vitamin A deficiency. The World Health Organization estimates 13.8 million children to have some degree of visual loss related to vitamin A deficiency. The causes of night blindness in children are multifactorial, and particular consideration has been given to childhood nutritional defic...
Article
Full-text available
The aim of the present study was to compare the level of copper (Cu), iron (Fe) and zinc (Zn) in biological samples (serum, blood, urine, and scalp hair) of patients suffering from different viral hepatitis (A, B, C, D, and E; n = 521) of both gender age ranged 31-45 years. For comparative study, 255 age-matched control subjects, of both genders re...
Article
Full-text available
Psoriasis is a noncontiguous common and chronic skin disorder. The aim of the present study was to compare the level of trace elements cadmium (Cd), chromium (Cr), Nickel (Ni), and zinc (Zn) in biological samples (whole blood, urine, and scalp hair) of psoriasis patients of both gender age ranged (25-55 years) at mild, moderate severe, and more sev...
Article
Full-text available
It has been speculated that trace elements may play a role in the pathogenesis of heart diseases In the present study, we aimed to access the levels of chromium (Cr) and manganese (Mn) in biological samples (whole blood, urine, and scalp hair) of myocardial infarction (MI) patients of both gender age ranged (45-60 years) at first, second, and third...
Article
Full-text available
The causes of night blindness in children are multifactorial, and particular consideration has been given to childhood nutritional deficiency, which is the most common problem found in underdeveloped countries. Such deficiency can result in physiological and pathological processes that in turn influence hair composition. This study was designed to...
Article
Full-text available
The causes of night blindness in children are multifactorial, and particular consideration has been given to childhood trace metals toxicity, which is the most common problem found in underdeveloped countries. This study was designed to compare the levels of cadmium (Cd), lead (Pb), and nickel (Ni) in scalp hair, blood, and urine of night blindness...
Article
The exposure of toxic elements may directly or indirectly associate with different pathogenesis of heart diseases. In the present study, the association of arsenic (As), cadmium (Cd), cobalt (Co), lead (Pb), and nickel (Ni) in biological samples (whole blood and urine) and mortality from myocardial infarction (MI) patients at first, second, and thi...
Article
Full-text available
Anemia affects a substantial portion of the world's population, provoking severe health problems as well as important economic losses to the region in which this condition is found. This study was designed to compare the levels of essential trace and toxic elements in scalp hair, blood, and urine samples of anemic children (n = 132) with age range...
Article
Full-text available
Anemia affects a substantial portion of the world's population, provoking severe health problems as well as important economic losses to the region in which this condition is found. This study was designed to compare the levels of essential trace and toxic elements in scalp hair, blood, and urine samples of anemic children (n = 132) with age range...
Article
The determination of essential trace and toxic elements in the biological samples of human beings is an important clinical screening procedure. This study aimed to assess the possible effects of environmental exposure on paralysed male workers (n = 75) belonging to the production and quality control departments of a steel mill. In this investigatio...
Article
Full-text available
The pathogenesis of some cardiovascular diseases (CVDs) has been altered with changes in the balance of certain trace and toxic elements. The aim of the present study was to assess the role of zinc (Zn) and cadmium (Cd) in smoker and nonsmoker male CVD patients (n = 457) of two age groups (31–45) and (46–60). The both elements were determined in bi...
Article
The most common cause of blindness in developing countries is vitamin A deficiency. The World Health Organization (WHO) estimates 13.8 million children have some degree of visual loss related to vitamin A deficiency. The causes of night blindness in children are multifactorial and particular consideration has been given to childhood nutritional def...
Article
Selenium (Se) has an essential role in thyroid hormone metabolism. It has the potential to play a major part in the outcome of iodine (I) deficiency The aim of the present study was to evaluate the Se and I status of biological samples (serum and urine) of 160 goitrous male (GMPs) and 195 female patients (GFPs). The supplemental effects of Se (200...
Article
The consequence of zinc (Zn) deficiency has been associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) disease progression and mortality. This study examined the association between low scalp hair and blood Zn concentrations and opportunistic infections in hospitalized patients with the acquired immune deficiency syndrome...
Article
The consequence of a deficiency in trace elements has been associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) disease progression and mortality. This study examined the association between low scalp hair and blood zinc, copper, and iron concentrations and opportunistic infections in hospitalized patients with the acqui...
Article
The aim of the present study was to compare the level of calcium (Ca), magnesium (Mg), potassium (K), and sodium (Na) in biological samples (serum, blood, urine, and scalp hair) of patients suffering from different types of viral hepatitis (A, B, C, D, and E; n = 521) of both genders, ages ranged between 31-45 years. For comparative study, 255 age-...
Article
The consequence of a deficiency in trace elements has been associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) disease progression and mortality. This study examined the association between high scalp hair and blood arsenic, cadmium, lead, and nickel concentrations and opportunistic infections in hospitalized patients w...
Article
The mechanism of transport of trace elements from the mother to the newborn is still not well known. The aim of present study was to compare the status of trace toxic elements, arsenic (As), cadmium (Cd), and lead (Pb) in biological samples (whole blood, urine and scalp hair) of insulin-dependent diabetic mothers (age ranged 30-40) and their newly...
Article
Full-text available
In many developing countries, men and women are at high risk of goiter and iron deficiency. The aim of the recent study is to assess the interaction of (Cu), with iron (Fe), iodine/iodide (I), and thyroid hormones in goitrous patients. Sixty goitrous male (GMPs) and 72 female patients (GFPs) were evaluated for the Cu, Fe, I, and thyroid hormones st...
Article
Epidemiologic studies suggest that zinc (Zn) deficiency and high accumulation of cadmium (Cd) may be associated with increased risk of cancer. The incidence of mouth cancer has increased among females, who possess habits of chewing tobacco with gradients (areca nut and betel quid) and smoking tobacco in Pakistan. In present study, we measured the c...
Article
Full-text available
There is compelling evidence in support of positive associations between zinc (Zn) deficiency and high accumulation of cadmium (Cd) in biological samples of different cancerous patients. The incidence of mouth cancer has been increased among people who possess habit of drinking alcohol, tobacco smoking and chewing with gradients in Pakistan. In the...
Article
The pathogenesis of some cardiovascular diseases (CVDs) has been altered with changes in the balance of certain trace and toxic elements. The aim of the present study was to assess the role of zinc (Zn) and cadmium (Cd) in smoker and nonsmoker male CVD patients (n = 457) of two age groups (31-45) and (46-60). The both elements were determined in bi...
Article
Full-text available
The objective of this study was to evaluate the association between trace and toxic elements zinc (Zn), cadmium (Cd), nickel (Ni) and lead (Pb) in biological samples (scalp hair, blood and urine) of smoker and nonsmoker hypertensive patients (n=457), residents of Hyderabad, Pakistan. For the purpose of comparison, the biological samples of age-matc...
Article
Many studies have examined the association between cardiovascular disease (CVD) mortality and the intake of essential micronutrients (potassium (K+), calcium (Ca(2+)), magnesium (Mg(2+)), and sodium (Na+)). They may separately reduce the CVD incidence to a small degree over the short term levels. The aim of the present study was to compare the leve...
Article
The determination of toxic metals (TMs) in the biological samples of human beings is an important clinical screening procedure. The aim of this work is to determine total content of TMs, aluminum (Al), cadmium (Cd), nickel (Ni), and lead (Pb) in scalp hair samples of chronic kidney male patients (CKPs) on maintenance hemodialysis, during the period...
Article
Objective There is accumulating facts that the metabolism of essential trace elements is altered in diabetic patients. The aim of present study was to compare the status of essential trace elements, chromium (Cr), manganese (Mn), and zinc (Zn) in biological samples (whole blood, urine and scalp hair) of insulin dependent diabetic mothers (age range...
Article
Full-text available
There is accumulative evidence that the metabolism of iron and copper is altered in viral hepatic diseases, and these nutrients might have specific roles in their pathogenesis and progress. The aim of present study was to compare the level of copper (Cu) and iron (Fe) in biological samples (serum, urine, and scalp hair) of female patients suffering...
Article
In the present study, the association of arsenic, cadmium, lead, and nickel between scalp hair samples and mortality from myocardial infarction (MI) patients at first, second, and third heart attack was studied. The biological samples of 130 MI patients (77 male and 53 female) age ranged (45–60years), were collected and 61 healthy persons of same a...
Article
The determination of trace and toxic elements in biological samples (blood, urine and scalp hair samples) of human beings is an important clinical test. The aim of our present study was to determine the concentration of arsenic (As), copper (Cu), cobalt (Co) and manganese (Mn), in biological samples of male production workers (PW) and quality contr...
Article
Zinc (Zn) is an essential element involved in many basic biochemical reactions in thyroid. The aims of present study is to evaluate the Zn status in biological samples and thyroid hormones levels in 60 goitrous male (GMPs) and 72 female patients (GFPs), before and after 6 months treatment with Zn supplementation and compared with non-goitrous subje...
Article
Full-text available
In many developing countries, women are at high risk of goiter and iron deficiency anemia (IDA). Iron deficiency adversely affects thyroid metabolism and may decrease the efficiency of thyroid hormones in areas of endemic goiter. The aim of the present study was to compare the level of iron (Fe) in biological samples (serum and urine) and serum thy...
Article
Full-text available
The determination of toxic elements in the biological samples of human beings is an important clinical screening procedure. The aim of this work was to determine total content of toxic elements-aluminum (Al), cadmium (Cd), and lead (Pb)-in whole blood and urine samples of male chronic renal failure patients (CRFPs) on maintenance hemodialysis from...
Article
There is accumulating evidence that the metabolism of several trace elements is altered in diabetes mellitus and that these nutrients might have specific roles in the pathogenesis and progress of this disease. The aim of present study was to compare the level of toxic elements, lead (Pb), cadmium (Cd), and arsenic (As) in biological samples (whole...
Article
Full-text available
There is accumulating evidence that the metabolism of several essential elements is altered in diabetes mellitus and that these nutrients might have specific roles in the pathogenesis and progress of this disease. The aim of the present study was to compare the level of essential elements, potassium (K), calcium (Ca), magnesium (Mg), and sodium (Na...
Article
Full-text available
There is accumulating evidence that the metabolism of several trace elements is altered in diabetes mellitus and that these nutrients might have specific roles in the pathogenesis and progress of this disease. The aim of present study was to compare the level of essential trace elements, chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel...
Article
The pathogenesis of some heart diseases has been associated with changes in the balance of certain trace elements. We examined the association of iron, copper and zinc between biological samples (scalp hair, whole blood and urine) and mortality from myocardial infarction (MI) patients of (first, second and third heart attack). The biological sample...

Citations

... Third, the samples we analyzed were taken between 10 and 14 weeks gestation, a key period in the development of preeclampsia. Finally, we measured iodide levels in serum, which recent research suggests may be more reliable and less subject to fluctuation than urinary iodine [23][24][25]. In one study serum iodine concentrations were significantly (p 0.002 to 0.007) correlated with thyroid stimulating hormone and free T3 and free T4 concentrations in hypothyroid patients. ...
... Extra absorbed Ca expelled out from the body through urine and skin in the form of sweat and feces. The normal level of Ca in nearly born baby is about 0.8 percent of the body weight whilst in adults it is about 1.7 percent of body weight (Afridi et al., 2015). Overall, our bones contain a total 99 percent Ca of the body, where it represents 39% of the complete body bone mineral substance [5]. ...
... The finally meta-analysis included 41 literatures [27,. Among them, 16 [27,[33][34][35][36][37][48][49][50][51][52][53][54][55]71,72], 23 [27,[33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][56][57][58][59][60]70,71] and 27 [27,[33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][61][62][63][64][65][66][67][68][69][70][71] articles presented the data of Se, Zn and Cu respectively. All of the included articles have assessed with acceptable quality scores (greater than three) conducted mainly in Europe and Asia with the earliest study published in 1975. ...
... Zanganeh et al., (23) also assessed serum levels of some trace elements, including copper, zinc, manganese, and magnesium in patients suffering from brucellosis, reporting elevated copper, and reduced zinc levels. Significantly reduced levels of chromium in the sera of tuberculosis patients and patients with HIV infection have also been reported (24,25). The higher prevalence of atherosclerotic cardiovascular disease in chromium deficient individuals was documented in a study conducted several years ago; however, it has recently been shown that chromium inhibits the expression of thrombospondin-1 (TSP-1), a potent proatherogenic protein that controls cell-cell and cell-matrix interactions (26). ...
... The nickel concentration was measured in blood, plasma and urine from obese and non-obese children and adolescents (aged 6-17 years); no correlation was found between the BMI and the concentration of nickel (Bla _ zewicz et al., 2013). Significantly lower nickel concentrations have been observed in the blood of rheumatoid arthritis patients than in controls (Irfan et al., 2017), and significantly higher nickel concentrations in the hair, blood and urine of hypertensive patients compared to controls (Afridi et al., 2014). Plasma levels of nickel were significantly higher in patients with Parkinson's disease (n = 225) than in healthy controls (n = 125) (Verma et al., 2016). ...
... Magnesium is a cofactor in >350 enzymatic reactions, with roles including protection from oxidative stress, and metabolism of calcium (Ca), vitamin D and potassium (Ebel and Günther 1980; Elin 1987; WHO and FAO 2004; Atkinson et al. 2009; Broadley et al. 2012; Deng et al. 2013; Das 2014; Dibaba et al. 2014; Rodríguez-Moran and Guerrero-Romero 2014). Deficiency in Mg can manifest as metabolic syndrome (Gartside and Glueck 1995; Hata et al. 2013; Rosanoff and Plesset 2013; Cosaro et al. 2014; Ju et al. 2014; Panhwar et al. 2014), lower bone-mineral density (Orchard et al. 2014), premenstrual syndrome (Elin 1987), and attention deficit hyperactivity disorder (Blaszczyk and Duda-Chodak 2013). Magnesium is obtained primarily from food sources, although drinking and cooking water can make important contributions depending on its hardness and the volume of water consumed (Ong et al. 2009). ...
... The link between HT and Zn status is not decisive, and contradictory findings are reported over the years. Some studies demonstrate an inverse association (76,77), while others found a direct positive link between serum Zn levels and blood pressure (57,78). There are also data signifying no association between the two variables (74)(75)(76)(77)(78)(79)(80)(81). ...
... Several advanced methods have been proposed for the quantitative determination of iodide ions which are reviewed in several recently published review articles [2][3][4]; among them spectrophotometric methods are the most common to date [5]. That's mainly because the techniques which avoid problems to destroy potential interfering substances, such as neutron activation analysis or inductively coupled plasma-mass spectroscopy, are unrealistic for widespread use, because of high cost, large sized and degree of sophistication [6]. On the other hand, the conventional UV-Vis spectrophotometry methods of iodide detection suffer from serious poor sensitivity [7] and they are very time consuming, for example, the most commonly used laboratory method for analyzing urinary iodine concentration which is based on Sandell-Kolthoff reaction [8], takes 3 days for one assay run [6]. ...
... It is known to aid in the transport of nutrients to lymphocytes and phagocytes, as well as in the protection of cell membrane. Oral NAC supplementation has shown positive results in improving the quality of life and well-being of patients faced with a wide range of genetic defects, metabolic disorders, and infections, including HIV infection [19] [21] indicated lower calcium, potassium, magnesium amongst male HIV patients and [22] also found lower calcium values in HIV infected individuals. Another study in Nigeria by [23] indicated a lower calcium & phosphorus levels in HIV/AIDS positive patients as compared to healthy HIV negative individuals. ...
... Biomedical tests, in hematology like red blood cells counts and white blood cells counts was performed, while in biochemistry cholesterol and urea tests was done in both groups (Afrid et al., 2013). ...