Narayanasamy Subbaraju Kannan’s research while affiliated with Mahatma Gandhi Medical College and Research Institute and other places

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Publications (9)


Eyelid Malignancies- Always Quite Challenging
  • Article
  • Full-text available

March 2017

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41 Reads

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11 Citations

Journal of Clinical and Diagnostic Research

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Narayanasamy Subbaraju Kannan

The diagnosis and management of eyelid cancers are quite challenging. Eyelid tumours are relatively rare diverse group of diseases varied in their presentation and extent. Many benign tumours and inflammatory conditions quite frequently masquerade eyelid cancers. Eyelid cancers are not single entity but comprise a wide range of tumours with extremes of tumour biology from indolent to very aggressive histopathologic types. Compromise on aesthetics and eyelids’ indispensable function of protecting the eyes during management, may lead to untoward cosmetic disfigurement and loss of vision. On the other hand, inadequate cancer clearance will also be vision threatening and life threatening due to loco regional recurrence and metastasis. To strike an optimal balance is a challenging task, to achieve ‘cancer cure’ with maximum preservation of function and cosmetics. In addition, the integration of other modalities of treatment, judicious selection and their sequencing require multidisciplinary discussion and joint management by different specialists. We are presenting four case scenarios, we met with in our teaching hospital with reference to literature review to emphasize that eyelid malignancies are not always simple with respect to diagnosis and management.

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Effectiveness of Centchroman on Regression of Fibroadenosis and Mastalgia

October 2016

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372 Reads

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14 Citations

Journal of Clinical and Diagnostic Research

Introduction: Fibroadenosis and mastalgia are common among the women in reproductive age group. Treatment for these conditions is not yet standardised. Most of the drugs used for fibroadenosis and mastalgia are expensive and have side effects. Aim: To find out the efficacy of centchroman, a Selective Estrogens Receptor Modulator (SERM) on regression of fibroadenosis and mastalgia. Materials and methods: Fifty one patients with mastalgia/fibroadenosis were treated with centchroman 30mg once daily on alternate days for a period of 3 months and followed up weekly for six months with Mastalgia chart and Visual Analog Scale (VAS) pain score. Results: Before starting treatment, four patients presented with pain score of 6 followed by, 37 patients with a score of 4 and 10 patients with a score of 2. All the patients were started on tab centchroman 30mg OD alternate days and were reviewed on weekly basis with Mastalgia chart and VAS pain score for three months. On fifth and sixth visit, 46 patients reported with pain score 0, one with pain score of 2 and four with pain score of 6. The efficacy of centchroman was found to be significant (p-value = 0.001). Three patients (5.9%) reported epigastric pain and ten patients (19.6%) reported menstrual delay. A total of 38 patients did not complain of any side effect. Conclusion: Our study proves that centchroman is a safe and cost effective drug with significant efficacy on regression of fibroadenosis and mastalgia with minimal side effect.



Penile Epidermal Cyst: A Case Report

May 2016

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207 Reads

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16 Citations

Journal of Clinical and Diagnostic Research

Epidermal cysts also known as epidermoid cysts, is one of the common benign tumours presenting anywhere in the body. However, epidermal cyst in the penis is very rare. This condition in children is usually congenital due to abnormal embryologic closure of the median raphe; hence, it is termed as median raphe cysts (MRCs). Penile epidermal cysts may occur in adults following trauma or surgery due to epidermal elements being trapped within closed space. During wound healing, trapped squamous epithelium, undergoing keratinisation leads to cyst formation. Here, we report a rare case of patient with a penile epidermoid cyst whose main complaints was discomfort during coitus.


Ainhum - A Rare Case Report

April 2016

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176 Reads

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11 Citations

Journal of Clinical and Diagnostic Research

The term ‘AINHUM’ is derived from the African word meaning ‘to saw or cut’. True ainhum otherwise called dactylolysis spontanea is a condition involving soft tissue or digits with constricting rings commonly presenting in fifth toes, usually bilateral. It is to be differentiated from Pseudo-ainhum that occurs secondary to some hereditary and nonhereditary diseases that lead to annular constriction of digits. We report a rare case of true ainhum involving the left fourth toe only. It is a very rare case and a very few were reported worldwide. The highest incidence of ainhum has been reported in South Africa and South America. It is rarely reported in India. Ainhum when diagnosed and treated in early stages can be prevented from progressing to mutilating deformities.


Congenital middle mesocolic hernia: A case report

December 2014

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19 Reads

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12 Citations

Australasian Medical Journal

Narayanasamy S Kannan

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Kannan Usha

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Thangamani Arun

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[...]

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Selvaraj Karthikesh

Internal hernia is herniation of a viscus, usually in the small bowel, through a normal or abnormal aperture within the peritoneal cavity. Its incidence has been reported to be one to two per cent. Internal hernias are classified based on location, and the hernial orifice can be either congenital or acquired. Paraduodenal hernias are the most common type (53 per cent). Paraduodenal hernia is often a misnomer and is referred to as a mesocolic hernia. Left and right mesocolic hernias are common, while middle and transverse types are rare. We are reporting a rare congenital middle mesocolic hernia presenting as a complete transection of the small intestine due to blunt injury to the abdomen.


Congenital Bilobed Gallbladder with Phrygian Cap Presenting as Calculus Cholecystitis

August 2014

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163 Reads

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14 Citations

Journal of Clinical and Diagnostic Research

The incidence of congenital bilobed gall bladder is 1 in 3000 to 4000. A Phrygian cap is a congenital abnormality of the gallbladder with an incidence of 4%. Preferred mode of diagnosis for Phrygian cap is cholescintigraphy and multi phase MRI, as Ultrasonography and CT are not always conclusive. The estimated prevalence of gallstone disease in India has been reported as 2% to 29%. A case of bilobed gall bladder with Phrygian cap in both the lobes and pigment gallstone in one of the lobes presenting as calculus cholecystitis is reported for its rarity and difficulty in arriving at correct preoperaive diagnosis.


Morphometric Study of Suprascapular Notch in Indian Dry Scapulae with Specific Reference to the Incidence of Completely Ossified Superior Transverse Scapular Ligament

March 2014

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97 Reads

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51 Citations

Journal of Clinical and Diagnostic Research

Background: The suprascapular notch, a depression on the lateral part of the superior border of the scapula, medial to the coracoid process, is bridged by the superior transverse scapular ligament, which is sometimes ossified and the foramen which is thus completed, transmits the suprascapular nerve to the supraspinatus fossa. Variations in the morphology of suprascapular notch have been identified as one of the causes of suprascapular nerve entrapment. Rengachary et al. classified this notch into six types, based on its shape. Aim of Study: To study morphological variations of suprascapular notch in Indian dry scapulae and to analyze the incidence of completely ossified superior transverse scapular ligament with other ethnic populations which have been cited earlier. Materials and Methods: A total of 400 human dry scapulae which were obtained from the Department of Anatomy of selected eight medical colleges were analyzed. The type of suprascapular notch was noted and it was recorded as per the description given by Rengachary et al. The results of the present study were compared with the results of previous authors in different populations. Results: In our study, out of 400 scapulae, 40 (10%), were identified to have completely ossified superior transverse scapular ligaments. The frequencies of various types of suprascapular notches were: Type I -20%, Type II -10%, Type III -52%, Type IV -4%, Type V -4%, Type VI -10%. Conclusion: Since the suprascapular nerve entrapment syndrome might be caused by complete ossification of superior transverse scapular ligament with formation of suprascapular foramen and other morphometric variations of suprascapular notch, the knowledge on such variations is essential for clinicians, for making a proper diagnosis and for planning the most suitable surgical intervention.


Citations (8)


... Paraduodenal hernias are considered to be the most common type of congenital internal hernias, and they are found in about 1-2% of the population. They are more common in males, and they usually present with SB obstruction between the fourth of sixth decades of their lives [66][67][68][69]. Three variants have been reported in literature; left, right and middle, with the left variant being the most common in 75% of the cases [69]. ...

Reference:

Facing the unexpected: unusual causes of mechanical small bowel obstruction in adults (A Systematic Review)
Congenital Middle Mesocolic Hernia: A Case Report
  • Citing Article
  • January 2014

Australasian Medical Journal

... As survival rates rise, maintaining quality of life post-treatment becomes paramount, as many patients live with long-term effects from the disease and its treatment (2). Surgery, chemotherapy, and radiotherapy can cause chronic conditions, including scarring, skin changes, and damage to mucosal barriers, often resulting in altered physical appearance (2,(4)(5)(6)(7)(8). These complications can be particularly severe for childhood cancer survivors, where functional and cosmetic issues involving muscle and soft tissues are common. ...

Eyelid Malignancies- Always Quite Challenging

Journal of Clinical and Diagnostic Research

... Certain drugs, like OCPs (oral contraceptive pills), estrogen and progesterone hormonal therapy, and certain antidepressants like SSRI (selective serotonin reuptake inhibitors) and antihistaminics, have also been linked to breast pain. [3] Ormeloxifene has been a centre of recent interest because of its beneficial effect in mastalgia and fibroadenoma regression as reported by multiple studies. Ormeloxifene can be used to suppress the proliferation of ductolobular tissue of fibroadenoma. ...

Effectiveness of Centchroman on Regression of Fibroadenosis and Mastalgia

Journal of Clinical and Diagnostic Research

... Criteria that proposed for the diagnosis by Khanna [2], there should be (i) surrounded by penile tissue, (ii) filled with keratin only, (iii) lined with surrounding fibrous connective tissue and (iv) with an inner lining of stratified squamous epithelium and without dermal appendages. The described case does not appear to fit the diagnosis, the authors founds a cyst lined by stratified epithelium squamous but it contained cheesy material, hair and clear jelly-like material, and classified it as congenital cyst of the penis of epidermoid type [3]. ...

Penile Epidermal Cyst: A Case Report

Journal of Clinical and Diagnostic Research

... Prior to any skin plasty procedures, infection must be cleared if underlying bone changes of the proximal phalanx are present recommendation is amputation disarticulation at the metatarsophalangeal joint. Relief of pain is reported immediately after both procedures [1,6]. Cole reported recurrence after z plasty did not occur within 8 months [1]. ...

Ainhum - A Rare Case Report

Journal of Clinical and Diagnostic Research

... 3 In addition, there is no specific imaging manifestation or laboratory findings to distinguish PDH from other pathologies. 4 All of these factors complicate diagnosis and may cause a delay in effective treatment which can result in strangulated intestinal obstruction, intestinal perforation or even death. 5 We describe here, a case in a young woman with acute intestinal obstruction where a large, left PDH was successfully identified and treated using a totally laparoscopic approach. ...

Congenital middle mesocolic hernia: A case report
  • Citing Article
  • December 2014

Australasian Medical Journal

... This condition is a benign variation, typically asymptomatic, and generally devoid of clinical significance [11,12]. Despite its harmless nature, the Phrygian cap may obscure clear imaging interpretation, sometimes mimicking gallbladder stones or suggesting a hepatic mass, potentially leading to misdiagnose during hepatobiliary imaging studies [11,13,14]. ...

Congenital Bilobed Gallbladder with Phrygian Cap Presenting as Calculus Cholecystitis

Journal of Clinical and Diagnostic Research

... Usha Kannan et al. studied 400 dry scapulae of the South Indian population and observed Type III SSN was prevalent and Type IV, V being less common which is similar to our study (50 scapulae) with incidence of Type IV was 20%. Although both the studies were done in the same South Indian population, results may be dissimilar due to the major difference in the sample size [17] . ...

Morphometric Study of Suprascapular Notch in Indian Dry Scapulae with Specific Reference to the Incidence of Completely Ossified Superior Transverse Scapular Ligament

Journal of Clinical and Diagnostic Research