Nair Aiswarya Hemachandran’s scientific contributions

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Publications (1)


An overview of insect derived bioactive compounds with therapeutic potential
  • Article

December 2024

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1 Citation

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Nair Aiswarya Hemachandran

Insects, among the most diverse groups of organisms, provide as a significant source of bioactive chemicals with therapeutic potential, historically utilized in medicine via honeybee products such as propolis and Apitoxin. Progress in molecular biology has unveiled their antibacterial, anti-inflammatory, anticancer, and neuroprotective properties. Antimicrobial peptides (AMPs) such as defensins and cecropins demonstrate effectiveness against drug-resistant bacteria, whereas bee venom, royal jelly, and propolis possess antioxidant and immunomodulatory characteristics. Challenges encompass sustainability, chemical variability, and scalability for pharmaceutical applications. Synthetic biology and biotechnology provide solutions; yet, ethical, regulatory, and quality concerns remain. This domain emphasizes the necessity of safeguarding insects and tackling global health issues such as antibiotic resistance and cancer, which could revolutionize pharmacological methodologies.

Citations (1)


... For instance, royal jelly, a nutrient-dense secretion consumed exclusively by queen bees, contains bioactive compounds such as 10-hydroxydecenoic acid and royalactin that significantly improve metabolic efficiency and contribute to the queen's exceptional longevity [56]. These compounds increase her capacity to utilize dietary sugars without succumbing to metabolic stress, suggesting a direct relationship between dietary composition and metabolic benefits [53,57]. Exploring the molecular mechanisms of royal jelly's effects could inspire dietary interventions in humans aimed at optimizing metabolic functions. ...

Reference:

Nature’s blueprint for sugar metabolism: translating bee and ant strategies into human diabetes therapies
An overview of insect derived bioactive compounds with therapeutic potential
  • Citing Article
  • December 2024