Nabamita Pal's research while affiliated with Netaji Subhash Chandra Bose Cancer Research Institute and other places
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Publications (12)
Aim: Adolescents cancer patients not only have substantial physical, cognitive, emotional and interpersonal problems but also added burden of a life threatening disease. Persistent body image concerns somatic preoccupation, disruptions in heterosexual relationships and deficit in social competence have all been documented in this age group. Integra...
DOI: http://dx.doi.org/10.2126/joim.v35i1.8897 Journal of Institute of Medicine, April, 2013; 35:45-49
Toto is one of the smallest tribes in the world. This primitive sub Himalayan, endogamous tribe lives in a small, isolated village called Totopara in the Jalpaiguri district of West Bengal in India. The tribal communities of West Bengal are vulnerable to various genetic disorders such as β-thalassemia (β-thal). We have studied 443 Totos to define t...
In India, breast cancer accounts for 25- 33% of all cancers in urban women and over 50% patients are diagnosed at late stages (III & IV), deeply impacting survival-rate. Statistics forecasts rural areas are 10% more likely to be affected with late-stage breast cancer. One of the strongest risk factors for developing breast cancer is preceded by lif...
5175
Background
India is in the Thalassemia belt of the world. Presently prevalence of Thalassemia carrier in India is 3.7% of its total population. Annual increment of Thalassemia carrier is 50,000. Both Alpha and Beta Thalassemia are found in West Bengal, a state in Eastern part of India. Beta Thalassemia is most common in West Bengal. Annual In...
5170
Background
The Thalassemias are a group of anemia that results from a genetic defect whch reduces the rate of synthesis of normal globin chains. Beta Thalassemia results in severe microcytic, hypochromic, haemolytic anaemia among affected patients. It has emerged as one of the most common health problems among the tribal populations in West B...
5113
Background
Toto is a primitive Indo-Bhutanese tribe residing in a small enclave called Totopara in the Jalpaiguri district of West Bengal, India. Toto culture and language is totally unique to the tribe, and is clearly distinguished from the neighboring Rajbongshis, Koch or the Bhutanese Sharchop tribes. Totos use to do consanguineous marriag...
5114
BACKGROUND
Thalassemia syndromes are a heterogeneous anemia caused by mutation affecting globin chains of the hemoglobin molecule. It is estimated that the average life span of Rabhas (tribal population of North Bengal, Jalpaiguri) range from 42 – 45 years. This raised a concern that they are perishing due to some genetic disease. Hence Scree...
Citations
... Recently, Candida has been reported as the most common nosocomial pathogen isolated from the urogenital tract of ICU patients [14]. The prevalence of candiduria in ICU patients was reported to be 19-44% [15]. In a study in Spain, 22% of patients who stayed more than seven days in ICU developed candiduria. ...
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... According to anthropologists, the Toto's language and culture are very unique and totally distinguished from the neighbouring tribes like Koch and Bhutanese Sharchop (Singh, 2014). Totos live in an elevated bamboo huts, identifying themselves as Hindu and practice kindred marriage, whereby they stay in the same neighborhood even after the marriage (Basak et al. 2009). They worship nature like river, canal, animal, forest, Kholanala (Khola-river, Nala-small canal) and their pghosallace of worship is called as Gohati (Gupta, 2013). ...
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... This in turn may increase the genetic load in terms of hemoglobin disorders through reduced level in infant and childhood mortality who will survive until their reproductive period for diagnosis and treatment. Once I hypothesized that together with demographic transition the frequency of the recessive genes like that of hemoglobin E may increase leading to genetic load in a population (Sikdar 2008a) and it became very much implicit with the studies among the Sonowal population of Assam (Barua and Kotal 2008) and Totos of West Bengal (Bhattacharyaa et al. 2013). This type of conjuncture can further be established with the help of restudy of different population groups on different abnormal hemoglobin variants over a particular period of time. ...
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... Antifungal susceptibility test [18][19][20][21][22] Mueller Hinton Agar (MHA) with glucose (2%) and methylene blue (0.5 µg/L per ml) was used. For preparation of Mueller Hinton with glucose and methylene blue (MHA-GMB), flooding procedure was done. ...
... During their day to day life they work hard for cultivation, collection of forest products (fruits, vegetables & tubers, firewood etc.) which give them a good health beside all the genetic problems. Majumdar et al. (2010) ...
... In yet another study from the tribal population of Assam and Tripura states, the percentage of Hb E cases reported were 50.0 and 55.0%, respectively [9]. In Manipur, also in the northeastern region, the incidence of Hb E was found to be 15.81, 6.3, 5.75 and 2.44% among Meitei, Hill Kabui, Koireng and Simte tribes, respectively [17], while the Toto tribe near West Bengal showed an incidence of 49.21% of Hb E heterozygotes and 19.19% Hb E homozygotes [18]. Hence, the prevalence of Hb E disorders is quite variable in the northeastern region of India. ...
