January 2011
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26 Reads
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8 Citations
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January 2011
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26 Reads
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8 Citations
... 5-HT2A is expressed widely throughout the central nervous system (CNS), participating in post synaptic transmission at most of the serotoninergic terminal rich areas, including the neocortex (mainly prefrontal, parietal, and somatosensory cortex) and the olfactory tubercle; high concentrations of 5-HT2A on the apical dendrites of pyramidal cells in layer V of the cortex have been proposed to modulate cognitive processes. Activation by the agonists of 5-HT2A induces hyper activation in CNS (Aghajanian 1999;Nichols, 2001;Hintzen, 2010;Passie, 2008;Barnes, 2011). ...
January 2011