N. L. Kunel’skaya's research while affiliated with Pirogov Russian National Research Medical University and other places

Publications (30)

Article
Over the past decades, surgical techniques have been improved, aimed at restoring the position of the nasal septum in case of its deformities. The attitude to the technique of the operation itself has changed, which consists in a sparing approach to the osteochondral skeleton of the nasal septum (NS). It should be noted that to date, the histologic...
Article
The review article provides a definition and classification of different nystagmus types, a comparative description of the central and peripheral vestibular nystagmus. The pathogenetic patterns of up-beating and down-beating nystagmus are accurately described. The features of nystagmus formation in various diseases are discussed, such as Wernicke e...
Article
Objective: The aim of the study is to evaluate the efficiency of the new repositioning maneuver for patients with horizontal canal cupulolithiasis benign paroxysmal positional vertigo (BPPV) to perform independently at home between doctor's sessions. Materials and methods: 28 patients with isolated horizontal canal cupulolithiasis BPPV were enro...
Article
The analysis of the causes of the pathology of the vocal apparatus in vocalists is carried out. 136 singers were investigated in age from 23 till 70 years old with length of service from 3 till 42 years. It is shown that the occurrence of diseases of the larynx is affected by the state of the vocal apparatus itself, the volume and intensity of the...
Article
Diagnosis of hypertrophy of the tonsils is traditionally based on data from mesopharyngoscopy. However, there are conflicting views on the possibility of determining the degree of hypertrophy of the tonsils during a routine examination of the pharynx. To date, several methods have been proposed for the diagnosis of tonsil hypertrophy, which have se...
Article
Tinnitus is one of the most common ENT complaints. The peculiarity of this disease is lack of objective measurements. It is hard to monitor evaluation of treatment results. The main reference points, such as the presence or absence of ear noise – are not sufficient to determine this pathology. Also, most of these patients have negative emotions con...
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Full-text available
The article describes the present-day approaches to the diagnostics and treatment of fungal infections of the larynx. The proportion of laryngomycosis in chronic inflammatory pathology is up to 24%, the main causative agents of laryngomycosis are yeast-like Candida fungi (up to 98%). The specific feature of treatment of patients with laryngomycosis...
Article
The review of domestic and foreign literature was conducted to identify the current terminology, diagnostic criteria, mechanisms of ethiopathogenesis, and the methods of treatment of psychogenic vertigo. The article covers the questions of combined approach to treatment, including vestibular rehabilitation combined with cognitive behavioral therapy...
Article
Full-text available
The objective of the present study was to elaborate the therapeutic algorithm for the treatment of laryngomycosis. We have examined a total of 430 patients suffering from chronic laryngitis including 100 ones (23.2%) having the fungal flora. Mycosis was diagnosed by the microscopic study of the stained preparations with the application of various t...
Article
The objective of the present study was to demonstrate the clinical significance and possibilities of diagnostics and treatment of the intra-adenoid cysts in the nasopharynx as exemplified by an original observation of an individual case. The cystic structures in the nasopharynx rarely manifest themselves clinically and are known to produce the non-...
Article
This article deals with the modern approaches to the diagnostics and treatment of fungal ear infection depending on the localization of the inflammatory process and the species of the causative fungal agent with special reference to the factors underlying the development of otomycosis under the present-day conditions based on the results of the ana...
Article
The objective of the present study was the analysis of the current state of the problem of the frequently ill children. The authors present the classification of the frequently ill children together with information concerning the influence of various factors on the incidence of pediatric pathologies with special reference to the major pathogenic a...
Article
Full-text available
Aim: The objective of the present study was to elucidate the mechanisms behind the compensation of the vestibular ocular reflex and evaluate the effectiveness of vestibular rehabilitation in the patients presenting with vestibular neuritis (VN) with the application of the video head-impulse test (vHIT) and the dynamic visual acuity test (DVAT). M...
Article
The objective of the present work was to study the influence of the dry extract from the leaves of Ginkgo biloba EGb 761 (used as monotherapy at a dose of 120 mg twice daily during 4 months) on the vestibular function of the patients presenting with cochleovestibular pathology of peripheral and mixed genesis. We present the results obtained by the...
Article
The objective of the present review of the literature is the analysis of the currently available data concerning etiology and pathogenesis of benign paroxysmal positional vertigo (BPPV). The special emphasis is placed on the modern hypotheses of BPPV formation that collectively account for not more than 15% of all known cases of this condition. The...
Article
At present, the skeptical attitude toward the term ≪cervical vertigo≫ (CV) predominates in the ENT-community. Such point of view is attributable to the absence of specific CV symptoms and well-defined diagnostic criteria. The present literature review was designed to consider the results of the clinical observations and experimental investigations...
Article
Full-text available
The objective of the present study was to evaluate the otolith function in the patients presenting with idiopathic benign paroxysmal positional vertigo (pBPPV) attributable to the occlusion of the posterior semicircular canal (PSCC) of the inner ear with the use of vestibular evoked myogenic potentials (VEMP). Cervical (cVEMP) and ocular VEMP (oVEM...
Article
Full-text available
This review describes the clinical manifestations, diagnostics and treatment of the patients with mobile third window phenomenon. Key words: third window phenomenon, semicircular canal dehiscence, large vestibular aqueduct syndrome, perilymphatic fistula.
Article
Full-text available
Over 150 years have elapsed since Prosper Meniere's described for the first time the clinical symptoms of the disease that is called by his name at the present time. Nevertheless, the etiology of this pathological condition remains unknown. It has been believed during many decades that the cause of Meniere's disease Is the presence of an excess flu...
Article
The objective of the present study was to elucidate the topographic features of the nerve fibers belonging to the acoustic and vestibular analyzers located in the intracranial cranial segment of human vestibulocochlear nerve (VCN). A total of 16 samples of the intracranial cranial segment of the human vestibulocochlear nerve isolated from the regio...
Article
In the course of previous investigations carried out in the Republic of Sakha (Yakutiya), we have identified the main molecular-genetic factor responsible for the hereditary impairment of hearing among the indigenous population (mostly the Yakuts).The disease was shown to be attributable to the c.-23+1G>A mutation localized in the splice donor site...
Article
The objective of the present study was to elucidate the prevalence of various forms of benign paroxysmal positional vertigo (BPPV) among the patients with the complaints of dizziness who had applied for the medical aid. The secondary objective was to evaluate the effectiveness of the newly developed algorithm for the diagnostics and treatment of va...
Article
The objective of the present work was to study the spectrum of bacterial pathogenic agents responsible for the development of acute otitis media under present conditions and to elucidate the relationship between the pathogen species and the clinical course of the inflammatory process in the middle ear. A total of 60 patients of either sex at the ag...
Article
The objective of the present work was to study syntopy of the artery of labyrinth using block-preparations of the posterior cranial fossa, variants of its branching-off from the vertebro-basiliar basin (VBB), and peculiar features of its anatomical structure. A total of 12 block-preparations of the posterior cranial fossa were available for the inv...
Article
This review article was designed to systematize the literature data concerning etiology, pathogenesis, diagnostics and treatment of exudative otitis media (EOM) in the children. The review is focused on the prevailing current tendencies in the approaches to the problems of etiology, diagnostics, and treatment of EOM in the children as exemplified b...
Article
The present review of the current literature concerning pathogenesis, formation of neurovascular conflict of the vestibulocochlear nerve, its epidemiology, clinical manifestations, diagnostics, and the methods for the surgical and conservative treatment is focused on the indications for decompression of the vestibulocochlear nerve and its effective...

Citations

... Л. И. Свержевского, оптимальная длительность противогрибковой терапии должна со-ставлять не менее 21 дня и включать препараты как системного, так и местного действия. Местную антимикотическую терапию можно осуществлять с помощью ингаляций с 0,01% раствором бензидилметил-миристоиламино-пропиламмония, ингаляций амфотерицина В. При сочетании микоза гортани и глотки лечение необходимо дополнять местной терапией фарингомикоза с использованием 1% раствора клотримазола или препарата нистатин [10,11]. Пациентам с гиперпластической формой ларингомикоза после завершения курса консервативной терапии показано также хирургическое лечение -удаление гиперплазированной слизистой оболочки голосовых складок, а в некоторых случаях биопсию измененных участков слизистой оболочки гортани для дифференциальной диагностики с раком гортани [8]. ...
... The major difference in our study is that rehab with the early DVA protocol was performed in acute and not in chronic patients. Interestingly, it was recently reported that the passive aVOR gain could be improved if UVH patients were enrolled for rehabilitation within 1 month after their acute symptoms [32], a result in total agreement with our data. Animal models of vestibular pathology have demonstrated that the acute stage constitutes a sensitive period, or opportunity window during which most of the plastic events are expressed and used to get an optimal functional compensation [21]. ...
... Regardless of previous reports of nystatin's low efficacy in some cases of Aspergillus otomycosis [4,22], our study showed a good result against Aspergillus mold, with only one recorded relapse. The third prescribed antimycotic was naftifine, an allylamine derivative for topical administration which, besides its antifungal effect, may have certain anti-inflammatory properties [23]. This drug seemed to be a good option for treatment, as we found only one patient with relapse. ...
... Previous studies have focused on the association between bone mineral density and BPPV [15,16]. However, no consensus has been reached among those studies, the results still have been controversial. ...
... which affects splicing of the GJB2 transcript (Angeli, 2008). This mutation has been reported at different frequencies among different populations and is especially frequent in the Mongolian, Yakut, Czech, Hungarian, and Turkish HL populations (Barashkov et al., 2016;Teryutin, Barashkov, Kunel'skaya, Pshennikova, and Solov'ev, 2016;Yuan et al., 2010). It appears that the mutation in East Asia and North and South America is not abundant and has the highest frequency in South Asia and parts of the Middle East. ...
... Нейроваскулярный конфликт (НВК) -это сдавление черепного нерва сосудом. Компрессии может быть подвергнут любой черепной нерв [1]. Самый известный НВК ассоциирован с классической невралгией тройничного нерва, симптомы, патогенез и этиология которой широко освещены в научной литературе [2]. ...
... По данным литературы, разрешение отолитиаза при проведении однократного маневра Epley наблюдается в 36-47% случаев [18,19]. По нашим данным, однократное выполнение маневра позволило полностью купировать отолитиаз лишь у 30,8% всех обследованных пациентов с ДППГ ЗПК. ...
... Exclusion criteria: (1) children with mixed deafness, (2) children with craniofacial deformities, (3) children not between 3 and 6 years old, (4) children with incomplete clinical follow-up data. (5) In follow-up, due to various reasons the ventilation tube indwelling time less than 6 month. ...