Mun’s research while affiliated with Pusan National University and other places

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Publications (3)


Figure 1. Synthesis of 4,7-dinitrazadecanoic-1,10-diacid.
Figure 2. Polymerization of energetic prepolymer.
Figure 3. 1 H-NMR and 13 C-NMR spectra of 4,7-Dinitrazadecanoic-1,10-diacid (DNDA) monomer.
Figure 4. 1 H-NMR spectrum of DNDA_DEG prepolymer.
Figure 5. DNDA_DEG prepolymer FT-IR spectra.

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Nitramine-Group-Containing Energetic Prepolymer: Synthesis, and Its Properties as a Binder for Propellant
  • Article
  • Full-text available

November 2019

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343 Reads

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9 Citations

Hwang

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Mun

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A composite solid propellant which generates high propulsive force in a short time is typically composed of an oxidizer, a metal fuel powder and a binder. Among these, the binder is an important component. The binder maintains the mechanical properties of propellant grains and endures several thermal and mechanical stresses in the engine. Several studies have been reported for the development of energetic propellant binders for increasing the propellant′s propulsive force. While several materials have been studied for the synthesis of energetic prepolymers, a nitramine-group-containing prepolymer is a suitable candidate because these types of prepolymers are less toxic and more cost-effective when compared to the traditional glycidyl azide polymers (GAP) and triazole-based prepolymers. Considering the lack of studies for the binder using a nitramine-group-containing prepolymers, we synthesized a nitramine-group-containing monomer and polymerized a nitramine-group-containing prepolymer. The prepolymer was then used for the preparation of the binder and its thermal and mechanical properties, as well as the effect of the plasticizer, were studied. The binder that was prepared using the prepolymer containing a nitramine-group showed very high elongation, tensile strength. Nitrate-ester (NE)-type plasticizer could reduce the glassy transition temperature (Tg)of the binder successfully. Also, high-energy is released due to the decomposition of the nitramine-group at around 245 °C, thus exhibiting the efficiency of the nitramine-group-containing prepolymer as an excellent energetic binder material.

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Features Recognition from Piping and Instrumentation Diagrams in Image Format Using a Deep Learning Network

November 2019

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6,433 Reads

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53 Citations

A piping and instrumentation diagram (P&ID) is a key drawing widely used in the energy industry. In a digital P&ID, all included objects are classified and made amenable to computerized data management. However, despite being widespread, a large number of P&IDs in the image format still in use throughout the process (plant design, procurement, construction, and commissioning) are hampered by difficulties associated with contractual relationships and software systems. In this study, we propose a method that uses deep learning techniques to recognize and extract important information from the objects in the image-format P&IDs. We define the training data structure required for developing a deep learning model for the P&ID recognition. The proposed method consists of preprocessing and recognition stages. In the preprocessing stage, diagram alignment, outer border removal, and title box removal are performed. In the recognition stage, symbols, characters, lines, and tables are detected. The objects for recognition are symbols, characters, lines, and tables in P&ID drawings. A new deep learning model for symbol detection is defined using AlexNet. We also employ the connectionist text proposal network (CTPN) for character detection, and traditional image processing techniques for P&ID line and table detection. In the experiments where two test P&IDs were recognized according to the proposed method, recognition accuracies for symbol, characters, and lines were found to be 91.6%, 83.1%, and 90.6% on average, respectively.


Figure 1. Protein quantification by SWATH acquisition and PCA for group clustering. (a) PCA showed 54.9% of the proteins (PC1) to be divided between healthy controls and patients with RA (vertical line). The plot represents the individual samples. Red and blue dots represent healthy controls and patients with RA, respectively. (b) Partial least squares-discriminant analysis (PLS-DA) showed the patient group with RA to be separated from healthy controls. (c) PC variable grouping based on expression pattern in healthy controls and patients with RA.
Figure 3. Pathway maps, process networks, and GO processes associated with proteins differentially expressed between healthy controls and patients with RA. (a) Pathway maps significantly associated
Figure 4. Dot plots and ROC curve of selected biomarker candidates in healthy controls and patients with RA. Proteins, significantly altered in patients with RA than in healthy controls, were selected. (a,b) Serum amyloid A4 protein and vitamin D-binding protein were compared between healthy controls and patients with RA. The number of healthy controls and patients with RA was 43 and 50, respectively. Plots indicate individual protein abundance of each group. Data are presented as mean ± SEM. Independent t-tests were used to determine statistical significance. **p < 0.001.
Figure 5. Logistic analysis of selected biomarker candidates in healthy controls and patients with RA. (a,b) The number of healthy controls and patients with RA for logistic analysis was 43 and 50, respectively. Classification accuracy was 86.0% and 81.4% in healthy controls and in patients with RA, respectively.
Proteomics Approach for the Discovery of Rheumatoid Arthritis Biomarkers Using Mass Spectrometry

September 2019

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111 Reads

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40 Citations

Rheumatoid arthritis is an autoimmune disease that causes serious functional loss in patients. Early and accurate diagnosis of rheumatoid arthritis may attenuate its severity. Despite a diagnosis guideline in the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for rheumatoid arthritis, the practical difficulties in its diagnosis highlight the need of developing new methods for diagnosing rheumatoid arthritis. The current study aimed to identify rheumatoid arthritis diagnostic biomarkers by using a proteomics approach. Serum protein profiling was conducted using mass spectrometry, and five distinguishable biomarkers were identified therefrom. In the validation study, the five biomarkers were quantitatively verified by multiple reaction monitoring (MRM) analysis. Two proteins, namely serum amyloid A4 and vitamin D binding protein, showed high performance in distinguishing patients with rheumatoid arthritis from healthy controls. Logistic analysis was conducted to evaluate how accurately the two biomarkers distinguish patients with rheumatoid arthritis from healthy controls. The classification accuracy was 86.0% and 81.4% in patients with rheumatoid arthritis and in healthy controls, respectively. Serum amyloid A4 and vitamin D binding protein could be potential biomarkers related to the inflammatory response and joint destruction that accompany rheumatoid arthritis.

Citations (3)


... Over recent decades the nitramine chemistry has been investigated intensively and has led to the creation of a variety of low-molecular high-energy density linear, cyclic and caged material [9][10][11][12]. By contrast, relatively few examples of the preparation of nitraminopolymers have been reported [13][14][15][16]. ...

Reference:

Nitramino-polymer with ether bridges and 1,2,3-triazole subunits incorporated into the polymer chain
Nitramine-Group-Containing Energetic Prepolymer: Synthesis, and Its Properties as a Binder for Propellant

... To understand the configuration and process flow in the field in a Centrifugal pump type overhung 4 size 4x11 system, it is important to look at the Piping and Instrumentation Diagram (P&ID). This diagram provides a complete overview of how the pump components are connected and how fluid flow occurs in the system (Yu et al., 2019). This will help in analyzing the causes of the sand deposits. ...

Features Recognition from Piping and Instrumentation Diagrams in Image Format Using a Deep Learning Network

... RA is a chronic autoimmune condition characterized by persistent debilitating joint inflammation [1]. Early diagnosis and timely intervention may lead to better prognosis of rheumatoid arthritis patients [2]. Due to the low sensitivity and specificity, current approaches often fail in RA early detection [3]. ...

Proteomics Approach for the Discovery of Rheumatoid Arthritis Biomarkers Using Mass Spectrometry