Mostafa M.E. Hamza's research while affiliated with Cairo University and other places

Publications (5)

Article
Purpose: To study the safety of extended monthly intravitreal infliximab injections in patients with active posterior uveitis in Behcet's disease (APUBD). Methods: This is a prospective, interventional, noncomparative, open-label, pilot study of 9 monthly intravitreal infliximab injections (1mg/0.05ml) for twenty-two eyes of 16 patients with APUB...
Article
Purpose: To assess the impact of COVID-19 pandemic on ophthalmology practice in Cairo metropolitan area. Methods: A cross sectional observational analytic study among ophthalmologists practicing in different hospitals in Cairo metropolitan area. The data was collected through a self-administered questionnaire covering general measures taken duri...
Article
Full-text available
Purpose: To assess the safety and efficacy of intravitreal infliximab (1 mg/0.05 mL) in patients with refractory posterior uveitis in Behcet's disease. Methods: Twenty patients were included in this study. Best corrected visual acuity (BCVA), vitreous haze (graded 0-4), vasculitis, retinitis, and papillopathy (presence or absence) were assessed...
Conference Paper
Purpose: To assess the safety and efficacy of intravitreal infliximab (1 mg/0.05 mL) in patients with refractory posterior uveitis in Behcet’s disease. Methods: Twenty patients were included in this study. Best corrected visual acuity (BCVA), vitreous haze (graded 0–4), vasculitis, retinitis, and papillopathy (presence or absence) were assessed at...
Conference Paper
Purpose: To assess the safety and efficacy of intravitreal infliximab (1 mg/0.05 mL) in patients with refractory posterior uveitis in Behcet’s disease. Methods: Twenty patients were included in this study. Best corrected visual acuity (BCVA), vitreous haze (graded 0–4), vasculitis, retinitis, and papillopathy (presence or absence) were assessed at...

Citations

... At 18 weeks of follow-up, they observed statistically significant improvements in mean visual acuity, reductions in mean central macular thickness, and decreased mean vitreous haze scores. In contrast, an open-label study of monthly intravitreal IFX injections reported a high ocular complication rate and failure to control BD uveitis, leading the authors to advice against this approach [38]. Studies have discovered that excessively high IFX concentrations in the vitreous cavity may provoke uveitis because of immune response; therefore, this therapy is recommended as an alternative treatment for patients who cannot tolerate systemic IFX medication [36]. ...
... 5 Importantly, these perceptions have been reflected in the literature. 6,7 In addition, ocular manifestations of the virus, including follicular conjunctivitis, epiphora or chemosis, may indicate the first presentation of COVID-19. 8,9 Similarly, ophthalmic consultations often require several examination techniques involving visual acuity, intraocular pressure measurements, and fundus examinations. ...
... Hamza et al. demonstrated the safety and efficacy of a single 1 mg/0.05 ml intravitreal IFX injection in 20 patients with refractory uveitis due to BD [37]. At 18 weeks of follow-up, they observed statistically significant improvements in mean visual acuity, reductions in mean central macular thickness, and decreased mean vitreous haze scores. ...