May 2025
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18 Reads
Journal of Mood and Anxiety Disorders
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May 2025
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18 Reads
Journal of Mood and Anxiety Disorders
December 2024
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26 Reads
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2 Citations
Effective emotion regulation is critical for maintaining emotional health in the face of adverse events that accumulate over the lifespan. These abilities are thought to be generally maintained in older adults, accompanied by the emergence of attentional biases to positive information. Such age-related positivity biases, however, are not always reported and may be moderated by individual differences in affective vulnerabilities and competencies, such as those related to dispositional negative affect and emotion regulation styles. To examine these relationships, we analyzed eye-tracking data from 72 participants (35–74 years; 50 female), 44 without and 28 with a diagnosis of Major Depressive Disorder during a free-viewing task comprising neutral-neutral, negative-neutral, and positive-neutral image pairs. Emotional bias scores were calculated based on the ratio of time spent dwelling on the emotional image vs. the neutral image in each emotional-neutral pair. Results indicate that healthy participants exhibited a stronger positivity bias than a negativity bias, whereas individuals with higher depressive symptom scores showed no difference. Next, we examined how age and emotion regulation strategy use (reappraisal vs. suppression, measured with the Emotion Regulation Questionnaire) impacted these effects. Individuals with Major Depressive Disorder did not exhibit a significant relationship between age and positivity bias. However, for healthy participants who self-reported a preference for using reappraisal in daily life, increased age was associated with an increased positivity bias. These findings indicate that the emergence of the positivity effect in older adults is related to reappraisal regulatory preferences in the absence of depressive symptoms.
December 2024
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38 Reads
Mind-wandering is an essential cognitive process in which people engage for 30–50% of their waking day and is highly associated with neuroticism. The current study identified the factor structure of retrospective self-report items related to mind-wandering and perseverative cognition content and explored these associations with neuroticism. In an adult community sample (N = 309), items from the NYC Cognition Questionnaire, the Penn State Worry Questionnaire Short Form, and the Rumination Responses Brooding Subscale were entered into factor analyses to test the optimal factor structure of these items. We employed a structural model to investigate associations of mind-wandering facets with neuroticism. A correlated three factor solution best fit the data (CFI = .94, TLI = .93, SRMR = .07, RMSEA = .07). Bifactor models failed to provide evidence for a general mind-wandering construct above and beyond variance explained by mind-wandering and perseverative cognition facets. The structural model revealed differential associations of each facet with neuroticism. A wandering mind is not always an unhappy mind. Whereas worry and rumination are associated with higher levels of neuroticism, mind-wandering has other components that relate to positively valenced cognition and lower neuroticism. Adaptive and maladaptive mind-wandering should be tested together in future studies of personality and psychopathology.
December 2024
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6 Reads
Neuroimage Reports
September 2024
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16 Reads
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1 Citation
August 2024
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27 Reads
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3 Citations
Behaviour Research and Therapy
May 2024
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30 Reads
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1 Citation
Journal of Affective Disorders
April 2024
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3 Reads
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1 Citation
American Journal of Geriatric Psychiatry
July 2023
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30 Reads
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2 Citations
This study assessed the relationship between modifiable psychological variables and depression, anxiety, and posttraumatic growth in women experiencing infertility. U.S. women (N = 457) who identified as experiencing infertility completed standardized self-report measures of mindfulness, self-compassion, positive affect, intolerance of uncertainty, relationship satisfaction, experiential avoidance, depression, anxiety, and posttraumatic growth. Clinical and demographic characteristics (age, duration trying to conceive, miscarriage, and childlessness) did not predict depression or anxiety. Lower positive affect and higher experiential avoidance were associated with depression and anxiety. Lower self-compassion was associated with depression; higher intolerance of uncertainty was associated with anxiety. There were indirect effects of mindfulness on anxiety and depression via these variables. Future research should explore whether intervening on these factors reduces depressive and anxiety symptoms. Promoting mindfulness may have beneficial effects on symptoms via its downstream effects on multiple coping variables. Counterintuitively, posttraumatic growth was associated with higher intolerance of uncertainty and experiential avoidance.
July 2023
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44 Reads
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4 Citations
Journal of Affective Disorders
Background: Growing evidence indicates that anhedonia is a multifaceted construct. This study examined the possibility of identifying subgroups of people with anhedonia using multiple reward-related measures to provide greater understanding the Research Domain Criteria's Positive Valence Systems Domain and pathways for developing treatments. Methods: Latent profile analysis of baseline data from a study that examined the effects of a novel kappa opioid receptor (KOR) antagonist drug on measures and biomarkers associated with anhedonia was used to identify subgroups. Measures included ventral striatal activation during the Monetary Incentive Delay task, response bias in the Probabilistic Reward Task, reward valuation scores from the Effort-Expenditure for Rewards Task, and scores from reward-related self-report measures. Results: Two subgroups were identified, which differed on self-report measures of reward. Participants in the subgroup reporting more anhedonia also reported more depression and had greater illness severity and functional impairments. Graphs of change with treatment showed a trend for the less severe subgroup to demonstrate higher response to KOR antagonist treatment on the neuroimaging measure, probabilistic reward task, and ratings of functioning; the subgroup with greater severity showed a trend for higher treatment response on reward-related self-report measures. Limitations: The main limitations include the small sample size and exploratory nature of analyses. Conclusions: Evidence of possible dissociation between self-reported measures of anhedonia and other measures with respect to treatment response emerged. These results highlight the importance for future research to consider severity of self-reported reward-related deficits and how the relationship across measurement methods may vary with severity.
... In a follow-up study, a larger parallel-arm randomized control trial (RCT) compared BATA and MBCT for clinically significant anhedonia in a transdiagnostic cohort of adults with clinically significant anhedonia (SHAPS ≥ 20). 70 Both treatments yielded substantial SHAPS reductions of~7 points without significant differences between them. Similarly, internalizing symptoms decreased in both conditions. ...
Reference:
Anhedonia: Current and future treatments
August 2024
Behaviour Research and Therapy
... The main definition of anhedonia is pleasure loss or decreased reactivity to pleasurable stimulus in any form. This symptom is implicated in diagnosing several psychological disorders, such as schizophrenia, post-traumatic stress disorder, and major depressive disorder [31]. Nevertheless, it is among the main symptoms during the onset of sickness behavior, contributing to the depressive state. ...
July 2023
Journal of Affective Disorders
... The age of infertile patients has also been studied, with diverse results. Some research indicates that age, specifically being over 30, is a predictive factor for anxiety in infertile couples (Drosdzol & Skrzypulec, 2009), while other studies do not find this relationship (Schuette et al., 2023;Wang et al., 2023) or only observe it in men (Kumar et al., 2023). ...
July 2023
... -By stimulating the DLPFC with rTMS, we aim to enhance its feedback control over subcortical structures. -By using odorants with positive hedonic value known to recruit/activate the reward circuit, we aim to enhance DA release and thereby increase ventral striatal activity which is reduced in anhedonia, Based on evidence linking anhedonia to reduced DA transmission and blunted mesocorticolimbic network functional connectivity (Phillips et al., 2023), we hypothesize that rTMS would alleviate depressive symptoms through changes in functional and effective connectivity within DA-related brain regions. ...
June 2023
Psychiatry Research Neuroimaging
... A randomized trial compared behavioral activation treatment for anhedonia (BATA) and mindfulness-based cognitive therapy (MBCT) in 73 transdiagnostic subjects. 69 While both treatments reduced SHAPS scores over time, no between-condition differences emerged. Critically, within-person homework completion predicted greater sessionto-session improvements in anhedonia, particularly in BATA when clinician-reported homework was considered. ...
Reference:
Anhedonia: Current and future treatments
April 2023
Behaviour Research and Therapy
... More precisely, reducing the level of perceived stress by early treatment was able to make changes in hedonic functioning during mid-late treatment. Therefore, what is especially vital for us is to evaluate new interventions for anhedonia to measure stress levels repeatedly [21]. Stress also is a well-validated predictor for the occurrence and relapse of depression [22,23], and depression has been confirmed by numerous experiments that reward-related function always changes [24]. ...
March 2023
Journal of Affective Disorders
... Conversely, di culties in emotional regulation can lead to various troubles for individuals and diminish their psychological motivation and mental health status [2]. Studies have found that emotional regulation di culties are closely related to mood and anxiety disorders, eating disorders, attention-de cit/hyperactivity disorder, conduct problems, self-harming behaviors, substance abuse, borderline personality disorder, and other psychological and behavioral problems [3,4,5,6,7]. ...
November 2022
Annals of Clinical Psychiatry
... To elicit a reward response, participants will complete a monetary incentive delay (MID) task during imaging. This task has previously shown sensitivity to altered reward-related dopamine release in a transdiagnostic anhedonia sample [35]. The first study objective aims to characterize the relationship between striatal reward responses and perimenopausal-onset anhedonia and psychosis symptoms at baseline. ...
July 2022
... 25 Women with infertilitypreferred behavioral interventions and were willing to practice coping skills and mindfulness to help manage the uncertainty and stress of infertility. 26 Mindfulness meditation improves emotional well-being and outcomes in infertility. 27 Group psychological interventions, (based on CBT and mindfulness) improved the mental health, fertility stress and pregnancy rates of women undergoing fertility treatment. ...
March 2022
Integrative Medicine Reports
... The capacity to experience likely also varies from person to person (cites in §2.1) and is likely amenable to alteration and training, as suggested by the effect of pain relief to dull emotional and even empathetic responses (Durso et al., 2015;Mischkowski et al., 2019), emotional blunting in SSRI treatments for depression (e.g., Goodwin et al., 2017), and therapeutic services both to reduce and increase the intensity of emotional experience (e.g., Engelhard et al., 2011; clinical trials on anhedonia, Phillips et al., 2022). Such context-dependency does not refute HTV. ...
March 2022