Mohammed Sheeraz’s scientific contributions

Background-Osteoarthritis is a global condition causing abnormal joint biomechanics and delayed articular cartilage deterioration, affecting the knee and affecting approximately 250 million individuals. It is a leading cause of impairment in the aged due to diabetes. Traditional treatments include pain medication, exercise, heat and cold therapy, corticosteroid injections, and joint repair or replacement surgery. The Unani medical system offers three treatment methods. 'Ilaj bi'l Tadbir (Regimenal Therapy), 'Ilaj bi'l Taghdhiya (Dietotherapy), 'Ilaj bi'l Dawa (Pharmacotherapy), and 'Ilaj bi'l Yad (Surgery), each with its own restrictions. Objectives-Efficacy of a topical Dimad in the management of Waja-al-Rakba (knee Osteoarthritis) and provide safe, effective and feasibly available with no or minimum side effect. Methods-A 40-year old female with bilateral knee pain and stiffness, diagnosed six months ago, presented to the OPD of the Regional Research Institute of Unani Medicine, Srinagar. Despite receiving analgesics, anti-inflammatory drugs, and physical therapy, she continued to deteriorate. In this study, a Dimad or medicated paste is applied over the anterior part of the left knee for two weeks daily twice a day for at least 15-20 minutes and then washed-out area with lukewarm water. Result-The study found that topical Dimad formulation effectively treated knee joint symptoms and inflammation. The patient's VAS scores decreased from 9 to 1 by the 14th day, indicating a decrease in symptoms. The treatment was safe and bearable, and the patient's quality of life improved significantly. After treatment, there was a statistically significant decrease in mean VAS ratings from day 0 to day 14. Conclusion-The patient reported a significant improvement in pain, stiffness, and soreness, and a significant decrease in mean VAS ratings from day 0 to day 14 after treatment.

ABSTRACT Background:- Frozen shoulder, also known as adhesive capsulitis, is the major cause of shoulder pain and disability in the general population. The prevalence is 2-5% in the general population and 10- 20% in diabetics. It typically affects females aged 40 to 60. In 12% of cases, both shoulders are affected, although the left shoulder is more frequently afflicted. Objectives:- In This case study our objective is to evaluate the efficacy of Fire Cupping (Ḥijāma Nāriyya) in Alleviating Symptoms of Waja‘al-Mafāṣil-i-Katif(Frozen shoulder). Methods:- A 61-year-old diabetic male patient presented to the OPD of the Regional Research Institute of Unani Medicine, Srinagar. Over a 4-week period, the affected shoulder was treated with Ḥijāma Nāriyya (fire cupping) on specific spots three times per week, with weekly assessments. Result- This study found that regimental therapy Ḥijāma Nāriyya (fire cupping) effectively reduces pain, stiffness, and increases mobility in the shoulder joint, as well as enhancing range of motion in frozen shoulder. The patient's VAS scores was decreased and also indicating a decrease in symptoms. Conclusion- The treatment was safe and bearable, and the patient's quality of life improved significantly. After treatment, there was a statistically significant decrease in VAS and Improvement in overall shoulder mobility.

This article reveals about Unani Concept of Dengue Fever (Hummae Danuj) and its management in Unani System of Medicine.

Polycystic Ovarian Syndrome (PCOS) is one of the commonest Endocrine disorders. It usually presents during adolescence with menstrual irregularities and weight gain, and with or without signs of hyperandrogenism such as acne and hirsutism. It often affects several family members and is aggravated by obesity. The incidence varies between 0.5 - 4 %. It is prevalent in young reproductive age group (20 -30%). Polycystic ovary may be seen in about 20% of normal women. In Unani System of Medicine, the disease has not been mentioned under the term of PCOS but the description of the disease has been described vividly by various Unani physicians under the headings of qillate tams (Oligomenorrhoea), ehtebas tams (amenorrhea), uqr (Infertility). The best known treatment of PCOS at present is by using allopathic medicines such as clomiphene citrate, metformin and tamoxifen. All these have mild to severe side effects including hot flushes, anorexia, nausea, metallic taste, flatulence, abdominal pain, mild diarrhoea, tiredness, vertigo and allergic dermatitis. So there is a need for alternative treatment. In order to provide safe and more effective medicine for PCOS, a meticulous attempt has been made in this review study to explore the utility of this age old drug Kalawnji (Nigella Sativa linn) in the management of PCOS.