Mohammad Murad's research while affiliated with Mayo Clinic - Rochester and other places

... In this theme issue, we have invited three author teams with specific expertise in methodology, to address a specific research type in the area of clinical microbiology and infectious diseases. They address state-of-theart methodology for designing primary studies on antimicrobial resistance, for designing systematic reviews of prognostic models, and evidence-based guidelines on diagnostic questions [12][13][14]. ...

... saliva, anteriornares [nasal] swabs, and oropharyngeal [throat] swabs) in some countries. Cross-sectional studies comparing paired specimen types from the same person have shown that cycle threshold (Ct, a semi-quantitative proxy for viral load) values can differ substantially between specimen types (10), and the clinical sensitivity of different specimen types is not equivalent (11). Sometimes, viral loads in one specimen type are low or even absent while viral loads in another type are high (12)(13)(14). ...

... These include patient values and preferences, acceptability, feasibility, cost, and equity, which will vary accordingly to local health care settings and across countries (54). These factors were carefully considered during the development of the Endocrine Society Clinical Practice Guidelines on the Management of Adult Patients with Hypercalcemia of Malignancy (55). ...

... The certainty of available evidence to support the recommendations to address 8 clinical scenarios formulated by the Endocrine Society Guideline panel was low to very low, underscoring the importance of shared decision making to account for the relevant contextual and decisional factors involved in the selection of care pathways. These include patient values and preferences, acceptability, feasibility, cost, and equity, which will vary accordingly to local health care settings and across countries (54). These factors were carefully considered during the development of the Endocrine Society Clinical Practice Guidelines on the Management of Adult Patients with Hypercalcemia of Malignancy (55). ...

... This variability may be partially explained by differences in disease prognosis between patients (17). Each recommendation was based on a systematic review (SR) that queried electronic databases for studies relevant to that question (18). The Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to assess the certainty of evidence for making the specific recommendations. ...

... [1][2][3][4] This Focus Issue on arrhythmias contains the contribution entitled 'Association between basic life support and survival in sports-related sudden cardiac arrest: a meta-analysis' by Laurianne Michelland from Université Paris Cité in France, and colleagues. 5 The authors evaluate the association of basic life support with survival after sports-related SCA (SR-SCA). In a systematic review and meta-analysis, a search of several databases from their inception to 31 July 2021 without language restrictions was conducted. ...

... A metaanalysis showed that the incidence of stroke and death within 30 days was 4.9%, and that after Day 30 was 3.7% [11]. Another meta-analysis revealed that the incidences of stroke and death within 30 days and after 1 year were 3 and 5%, respectively [12]. The incidence of perioperative complications related to balloon angioplasty alone for symptomatic stenosis of the MCA was reported to be 4.2% [13]. ...

... A study reported that fever, cough, dyspnea, myalgia, and fatigue are the most common, and expectoration, headache, hemoptysis, and diarrhea are the least early symptoms of covid-19 in pregnant women [3]. Based on a systematic review of published articles, the clinical manifestations of pregnant women infected with COVID-19 were similar to non-pregnant infected people [5]. Based on preliminary evidence, pregnant women may be more susceptible to SARS-CoV-2 due to adaptation to physiological and immunological changes [3]. ...

... Specifically, HTA has been associated with elevated liver enzymes, liver steatosis and advanced fibrosis, independent of body mass index (BMI), metabolic factors (e.g. abdominal obesity, diabetes, dyslipidemia), alcohol use and other relevant confounders in numerous studies 3,[6][7][8][9][10][11][12][13][14][15][16][17][18] . For example, a cross-sectional study based on data from 16,082 individuals in 26 cohorts found systolic blood pressure (SBP) to be independently associated with advanced liver fibrosis 17 . ...

... Debido a la falta de un estudio que sintetice las terapias para CU leve a moderada, los autores justifican este metaanálisis. 7 Presentan una conclusión interesante dado que de forma inicial pudiera pensarse que los esteroides tienen mayor potencia: concluyen que en pacientes con CU leve o moderada, la combinación oral y tópica y las dosis altas de mesalazina son superiores a la mesalazina en dosis estándar para inducir la remisión. ...