Mohammad Mozafarinia's research while affiliated with Persian Gulf University and other places

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Publication (1)

In vitro breast cancer targeting using Trastuzumab-conjugated mesoporous silica nanoparticles: Towards the new strategy for decreasing size and high drug loading capacity for drug delivery purposes in MSN synthesis
Article
  • Feb 2021
In the present study, an efficient protocol was introduced for synthesis of biocompatible mesoporous silica nanoparticles (MSN) with an adequate size and high drug loading capacity. Herein, the tri-ethanolamine, TEA, dominantly controlled the pH of solution in addition to regulate nanoparticle sizes via complexing with ortho silicate functional gro...
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Citations

... GSH refers to a major antioxidant in cells that counteracts oxidative stress [19]. Tumor cells exhibit higher levels of GSH than normal cells in response to a high oxidative state [20], thus meeting the requirements of metabolism and malignant proliferation [21]. When intracellular GSH is depleted, there is an imbalance in the intracellular redox state, which induces apoptosis in cells [22]. ...
Reference: Glutathione-responsive mesoporous silica nanocarriers for chemo–photothermal–photodynamic therapy of cancer
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