Mitchel P. Goldman MD's research while affiliated with La Jolla Pharmaceutical and other places

Publications (4)

Article
Introduction: Photodynamic therapy (PDT) is commonly used to treat actinic keratoses, superficial cutaneous carcinoma, photodamage, and/or acne. The aim of this study was to compare the usefulness of Avène thermal spring water (ATSW), a low mineral content spring water, to a high mineral content spring water. We evaluated post-PDT clinical symptom...
Article
Objective: To demonstrate the efficacy of duplex-guided foam sclerotherapy measured against patient symptom relief and quality of life. Methods: An analysis was performed of 100 randomly chosen legs with varicose veins treated with ultrasound-guided foam sclerotherapy with a mean follow-up of 22.5 months. Results: An average number of 2.1 trea...
Article
Laser resurfacing with the 950 μs pulsed CO2 laser is an effective treatment for photodamage and acne scarring; however, the potential for prolonged erythema and delayed re-epithelialization dissuade many patients from the procedure. With the use of erbium lasers alone, there is a decrease in the incidence and severity of these adverse sequelae; ho...
Article
Background. A new generation of highly selective short-pulsed lasers has emerged in recent years for the treatment of tattoos. Several studies (including reports by the present investigators) have proven the efficacy of each of the three commercially available, FDA approved devices; namely, the Q-switched alexandrite, Q-switched Nd:YAG and Q-switch...

Citations

... In recent years, laser-induced hyperthermia has garnered attention as a method for selectively destroying only cancer cells (Rostan et al., 2001;Sajjadi et al., 2013). To achieve selective heating against cancer cells, some laser hyperthermia methods have been proposed. ...
... Among the eligible patients, C2 clinical type was the commonest, followed by C4 and then by C5 and C6, respectively, which was in accordance with previous studies [3,[9][10][11][12]]. An improvement of the C component of CEAP score was seen in all treated patients at 2 months; however, the mean improvement in C score was not significantly different between the two groups. ...
... 69 Thermal spring water, which is a low-mineral-content spring water, can also be useful after ALA-PDT and is effective for reducing postprocedure cutaneous inflammation and patient discomfort. 82 Each provider may recommend their choice of soothing creams and/or sunscreens. Adverse events that have occurred in 10 percent of patients with AKs treated with ALA 10% gel include transient application site erythema, pain/burning, irritation, edema, pruritus, exfoliation, scab, induration, and vesicles. ...
... Recently, Q-switching in the 2 micron region has received increasing interest due to its various applications such as optical communications 7 , remote sensing 8 and in particular for biological and medical applications 9 . Q-switched lasers operating at 2.0 µm have been demonstrated for various applications such as the treatment of skin discoloration due to melasma pigmentation 10-12 by multiple passes with a large spot size laser 13 , as well as for the removal of tattoos [14][15][16][17][18][19] . Additionally, Q-switched fiber lasers operating at this region are also highly suitable for micromachining applications such as engraving 20-24 , cutting 25,26 , micro-welding 27,28 and drilling 29,30 . ...