Miseon Kim's research while affiliated with Ulsan University Hospital and other places

Publications (67)

Article
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We aimed to evaluate the clinical impact of shift patterns at work on gynecologic problems and the healthcare behavior of Korean nursing staff. We conducted a web-based survey for over two weeks in September 2021, involving female nursing staff, including nurses, nurses' aides, and nursing assistants, working in five medical centers. The questionna...
Article
Purpose: This study aimed to evaluate the cumulative recurrence rate and risk factors for recurrent abdominal wall endometriosis (AWE) after surgical treatment. Materials and methods: A retrospective cohort study was conducted at a single gynecological surgery center between January 2004 and December 2020. Patients who were surgically treated an...
Article
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Background Ovarian “seromucinous carcinoma” has been recently removed in 2020 5th Edition of WHO classification of Female Genital Tumors and is considered as a subtype of endometrioid carcinoma with mucinous differentiation, while “seromucinous borderline tumor” remains and exists as a distinct entity. Both diseases may be considered as no more sam...
Article
Background: This study aimed to assess the human papillomavirus (HPV) vaccine uptake rate in South Korean women and to identify factors affecting vaccination rate before initiation of the national HPV vaccination as a National Immunization Program (NIP) in Korea. Materials and methods: We conducted online survey in February 2016 with questions to 2...
Article
Aim: The aim of this study was to evaluate the clinical performance for detecting cervical intraepithelial neoplasia (CIN) 2 or higher lesions among available human papillomavirus infection (HPV) genotyping tests in Korea. Methods: Eligible patients visited 13 tertiary hospitals for colposcopic biopsy following cervical cytology and HPV genotypi...
Article
We conducted a survey to evaluate the awareness of genetic counseling and testing for hereditary gynecologic cancers among Korean healthcare providers. We performed an on‐the‐spot survey using 29 questions on respondents’ basic information, awareness of pre/post‐test genetic counseling, genetic information management, and related social issues. We...
Article
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During the COVID-19 pandemic, there are concerns about medical delay, including confirmatory tests after screening for various cancers. We evaluated the lead time to a confirmatory test after an abnormal screening Papanicolaou (Pap) test in women before the COVID-19 period and during the COVID-19 period. The medical records of 1144 women who underw...
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Background: Cervical cancer is the fourth common cancer in women worldwide. The Papanicolau test is the primary screening procedure to detect abnormal cervical cells. Colposcopy is the main procedure for discriminating high-grade cervical lesions. The study aimed at clarifying the discrepancy between cervical cytology and colposcopic biopsy histol...
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We aimed to determine clinical factors predicting successful pregnancy by comparing pregnancy failure and success groups after adenomyomectomy. Additionally, we analyzed fertility outcomes after adenomyomectomy.The medical records of 43 patients who had undergone adenomyomectomy and received in vitro fertilization treatment from 2017 to 2020 were r...
Preprint
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We aimed to estimate the positive predictive value of fluorodeoxyglucose positron emission tomography (FDG PET) to detect lymph node metastasis in patients with microinvasive cervical cancer who recently underwent conization. We retrospectively collected data of patients fulfilling the following criteria: 1) cervical cancer stage 1A1 (by FIGO stagi...
Article
Purpose: This study aimed to evaluate the risk of cervical cancer diagnosed within 1 year after the last of multiple consecutive normal Papanicolau (Pap) tests. Materials and methods: The database of the National Health Insurance Service was used. We obtained Pap test data for 11,052,116 women aged 30-79 between 2007-2012. The cumulative inciden...
Article
Objective: To investigate clinical features that affect the number of pelvic lymph nodes (PLNs) harvested and prognostic significance of the number of PLNs removed in patients with stage IB1 to IIA2 cervical cancer. Methods: Data from patients with cervical cancer whom underwent hysterectomy with PLN dissection between June 2004 and July 2015 we...
Article
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The aim of this study was to evaluate the rate of and risk factors for recurrence ovarian endometrioma after conservative surgery in patients aged 40-49 years. This retrospective, single-center study included 408 women between January 2008 and November 2018. All patients underwent ovarian cyst enucleation, were pathologically diagnosed with ovarian...
Article
Objectives: The aims of this study were to evaluate the clinical characteristics and recurrence rate of atypical endometriosis (AE)1 compared to typical endometriosis (TE) in addition to the malignant transformation rate among a large cohort. Study design: The medical records of 2681 patients who had undergone surgical treatment of ovarian endom...
Article
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Objective: To introduce a new surgical technique for specimen removal during laparoscopic surgery. Methods: The surgical technique was described, pictured, and recorded. The surgery was performed in a tertiary hospital. Results: During laparoscopic surgery, the specimen is resected from the surrounding tissues and contained in a specimen bag t...
Article
Background We hypothesized that the total operative time of robot myomectomy (RM) is shorter than that of laparoscopic myomectomy (LM) in cases where numerous myomas are removed, due to the faster suturing time of the robotic system. To verify this, we compared the surgical outcomes of RM vs LM for the number of myomas removed. Methods The medical...
Article
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In 2019, 12 topics were selected as the major research advances in gynecologic oncology. Herein, we first opted to introduce the significant clinical activity of pembrolizumab in women with advanced cervical cancer based on the results of the phase 2 KEYNOTE-158 trial. Thereafter, we reviewed 5 topics, including systemic lymphadenectomy in the adva...
Article
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Objective To evaluate the risk of encountering unexpected uterine smooth muscle tumors of uncertain malignant potential (STUMPs) or sarcomas during surgical treatment of mesenchymal tumors of the uterus using morcellation. Material and methods Data were collected retrospectively from subjects who were pathologically diagnosed with uterine leiomyom...
Article
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Based on emerging data and current knowledge regarding high-risk human papillomavirus (hrHPV) testing as a primary screening for cervical cancer, the Korean Society of Obstetrics and Gynecology and the Korean Society of Gynecologic Oncology support the following scientific facts: • Compared to cytology, hrHPV screening has higher sensitivity and de...
Article
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Cervical cancer is still one of the most common female cancers in Asia and the leading cause of cancer-related deaths in low- and middle-income countries. Nowadays, national screening programs for cervical cancer are widely provided in Asian countries. We reviewed the National Cancer Screening Program (NCSP) in China, India, Indonesia, Japan, Korea...
Article
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We aimed to discover cell line‐specific overexpressed HOX genes responsible for chemoresistance and to identify the mechanisms behind HOX‐induced cell line‐specific chemoresistance in EOC. Ten HOX genes and eight EOC cell lines were tested for any cell line‐specific overexpression that presents a mutually exclusive pattern. Cell viability was evalu...
Article
Background: To introduce a hybrid robotic single-site myomectomy (H-RSSM) technique that includes laparoscopic single-site myoma excision followed by robotic single-site suture and compare its surgical outcomes with those of conventional robotic single-site myomectomy (RSSM) using the da Vinci Si surgical system. Methods: Medical records of 89 c...
Article
Full-text available
Based on emerging data and current knowledge regarding high-risk human papillomavirus (hrHPV) testing as a primary screening for cervical cancer, the Korean Society of Obstetrics and Gynecology and the Korean Society of Gynecologic Oncology support the following scientific facts: • Compared to cytology, hrHPV screening has higher sensitivity and de...
Article
Full-text available
On the basis of emerging data and the current understanding of minimally invasive surgery (MIS) for radical hysterectomy (RH) in women with cervical cancer, the Korean Society of Gynecologic Oncology, Korean Society of Obstetrics and Gynecology, and Korean Society of Gynecologic Endoscopy and Minimally Invasive Surgery support the following recomme...
Article
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Objective To compare the survival outcomes of adjuvant radiotherapy and chemotherapy in women with uterine-confined endometrial cancer with uterine papillary serous carcinoma (UPSC) or clear cell carcinoma (CCC). Methods Medical records of 80 women who underwent surgical staging for endometrial cancer were retrospectively reviewed. Stage I UPSC an...
Article
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Circulating tumor cells (CTCs) have received enormous attention as a novel biomarker in various malignant diseases. We investigated the clinical association between the presence of perioperative CTCs and survival outcomes in women with ovarian cancer. In a total of 30 women who were scheduled to undergo a surgical treatment for ovarian cancer, peri...
Article
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We aimed to investigate the feasibility of robotic adenomyomectomy and compared surgical outcomes between laparoscopic and robotic approaches for adenomyomectomy.We retrospectively reviewed the data of women who were diagnosed with adenomyosis and underwent adenomyomectomy through a minimally invasive approach between January 2014 and March 2018 at...
Article
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Background Outcomes of patients with ovarian high-grade serous carcinoma (HGSC) treated with neoadjuvant chemotherapy (NAC) have been widely studied, but there is limited information on the outcomes of patients with non-HGSC. This study aimed to evaluate the outcomes of NAC in non-HGSC patients with advanced-stage ovarian cancer. Methods We conduc...
Article
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Nineteen topics were selected as major clinical research advances in gynecologic oncology in 2018. For cervical cancer, the importance of human papillomavirus (HPV) testing alone as primary cervical cancer screening method and negative survival impact of minimally invasive surgery in early-stage cervical cancer were addressed. For ovarian cancer, c...
Article
Background: Oligonol, a low molecular weight polyphenol derived from lychee fruit, not only has anti-inflammatory effects in various disease conditions but also has antitumor-promoting effects. We evaluate the nuclear factor-kappa B (NF-κB)-related anticancer effect of oligonol in ovarian cancer using SKOV-3 cells. Methods: Cell viability was exami...
Data
Kaplan-Meier curves of PFS rates by adjuvant therapy in stratified groups by LVSI and MI.
Data
Kaplan-Meier curves of OS rates by adjuvant therapy in stratified groups by LVSI and MI.
Article
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Objective To investigate the incidence and trends of cervical (C53), endometrial (C54.1), and ovarian cancer (C56) among Korean females between 1999 and 2015. Methods The incidence of the three major gynecological cancers between 1999 and 2015 was analyzed based on the data from the Korea Central Cancer Registry. The age-standardized rates (ASRs)...
Article
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Objective To evaluate the feasibility of robotic single-site myomectomy (RSSM). Methods Medical records of 355 consecutive women who underwent robotic-assisted laparoscopic myomectomy were retrospectively reviewed. Clinical characteristics were compared between multi-site and single-site systems. After 1:1 propensity score matching for the total m...
Data
Incidence rates per 100,000 (1999 and 2015) and APC of gynecologic cancer by subsite and age groups in female patients in the Korea Central Cancer Registry, 1999–2015
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[This corrects the article on p. 542 in vol. 61, PMID: 30254990.].
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Background: Bmi1, a polycomb group gene, is essential for self-renewal of stem cells and is frequently upregulated in various cancer cells. We aimed to investigate the effect of Bmi1 silencing on cancer stemness and chemosensitivity in endometrial cancer using targeted siRNA approach in HEC1A and Ishikawa cells. Methods: Cell viability after tre...
Article
Background To evaluate the feasibility and clinical outcomes of robotic single‐site myomectomy (RSSM) for uterine myoma Methods Medical records of 101 consecutive women who underwent RSSM were retrospectively reviewed, and patient characteristics and surgical outcomes were evaluated. The surgical outcomes were compared by the phase in learning cur...
Article
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Based on the current understanding of a preventive effect of bilateral salpingectomy on ovarian/fallopian/peritoneal cancers, the Korean Society of Obstetrics and Gynecology, Korean Society of Gynecologic Endocrinology, Korean Society of Gynecologic Oncology, Korean Society of Maternal Fetal Medicine, and Korean Society for Reproductive Medicine su...
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Objective: To evaluate survival impact of low anterior resection (LAR) in patients with epithelial ovarian cancer (EOC) grossly confined to the pelvis. Methods: We retrospectively reviewed 397 patients who underwent primary staging surgery for treatment of 2014 International Federation of Gynecology and Obstetrics (FIGO) stage II-IIIA EOC: 116 (...
Article
Objective: Randomized studies have not demonstrated a survival benefit of routine lymph node dissection in early-stage endometrial cancer. Many surgeons nevertheless perform lymph node dissection in all patients with early-stage endometrial cancer. This study aimed to ascertain the survival outcomes of very low-risk endometrial cancer patients (by...
Article
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In 2017, 10 topics were selected as major clinical research advances in gynecologic oncology. For cervical cancer, efficacy and safety analysis results of a 9-valent human papillomavirus (HPV) vaccine and long-term impact of reduced dose of quadrivalent vaccine were updated. Brief introduction of KEYNOTE trials of pembrolizumab, a monoclonal antibo...
Article
Aim: To investigate whether a concern for future pregnancy is reflected in the extent of large loop excision of the transformation zone (LLETZ) and to assess the clinical outcome. Methods: We reviewed the medical records of 275 women who underwent LLETZ for precancerous lesions in cervix. We divided them into two groups according to pregnancy po...
Article
Background: Anticancer effect of ginsenoside Rh2 has been found in various cancer cells. However, the anticancer effect of Rh2 in endometrial cancer cells is still unclear. We aimed to determine the anticancer effect of Rh2 and elucidate its mechanism in endometrial cancer cells, using HEC1A and Ishikawa cell lines, in this study. Methods: Cell...
Data
Univariate and multivariate analyses of risk factors for complicated lymphocele
Article
Background/aim: To investigate the abundance of programmed death-ligand 1 (PD-L1) expression and identify rational candidates for anti-PD-1/PD-L1 immunotherapies in cervical cancer. Patients and methods: In 27 patients with FIGO stage IB1-IIA cervical cancer, paraffin-embedded tumors were immunohistochemically stained with PD-L1 antibody. The co...
Data
Nomogram for the risk of development of postoperative complicated lymphocele in gynecologic cancer patients. IPC, intermittent pneumatic compression; PLN, pelvic lymph node.
Article
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Objective The purpose of this study is to estimate the risk of postoperative lymphocele development after lymphadenectomy in gynecologic cancer patients through establishing a nomogram. Methods We retrospectively reviewed 371 consecutive gynecologic cancer patients undergoing lymphadenectomy between 2009 and 2014. Association of the development of...
Article
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The aim of this study was to evaluate circulating tumor cell (CTC) detection in the differential diagnosis of adnexal masses. A total of 87 preoperative women with an indeterminate adnexal mass were prospectively enrolled. Preoperative diagnostic modalities including CTC detection, risk of ovarian malignancy algorithm, risk of malignancy index, and...
Article
Objectives: To investigate favorable factors of nerve-sparing radical hysterectomy (NSRH) for preserving the pelvic autonomic nerves and subsequent bladder function and to compare the safety between NSRH and conventional radical hysterectomy (CRH) for cervical cancer. Methods: We recruited 87 consecutive patients with IB1-IIA cervical cancer who...
Data
The search strategy and number of studies identified for inclusion in this meta-analysis.
Data
Funnel plots with Egger's test indicating no publication bias in this meta-analysis for the effect of elevated plasma fibrinogen levels on (A) PFS and (B) OS in patients with EOC. EOC, epithelial ovarian cancer; OS, overall survival; PFS, progression-free survival.
Data
Unfavorable factors affecting PFS and OS in 217 patients with advanced-stage EOC
Data
NOS for assessing qualities of 5 cohort studies for this meta-analysis
Data
Kaplan-Meier curves for (A) PFS and (B) OS broken down by the value of 400 mg/dL of plasma fibrinogen levels. OS, overall survival; PFS, progression-free survival.
Article
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In 2016, 13 topics were selected as major research advances in gynecologic oncology. For ovarian cancer, study results supporting previous ones regarding surgical preventive strategies were reported. There were several targeted agents that showed comparable responses in phase III trials, including niraparib, cediranib, and nintedanib. On the contra...
Article
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Objective: To evaluate the effect of elevated plasma fibrinogen levels on the prognosis of epithelial ovarian cancer (EOC). Methods: We reviewed the data of 217 patients with advanced-stage EOC between 2000 and 2012, and investigated the prognostic role of elevated plasma fibrinogen levels compared with serum CA-125 levels, neutrophil to lymphoc...
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Objective To evaluate the efficacy of loop electrosurgical excision procedure (LEEP) combined with cold coagulation for treating cervical intraepithelial neoplasia (CIN). Methods We reviewed clinic-pathologic data of 498 patients treated with LEEP alone (n=354), and LEEP combined with cold coagulation (n=144) between January 2000 and December 2011...
Article
Objectives: The aims of study were to determine the predictive value of preoperative magnetic resonance imaging (MRI) for parametrial invasion (PMI) and to develop a predictive model for PMI in patients with stage IB1 to IIA2 cervical cancer. Methods: We retrospectively analyzed patients with stage IB1 to IIA2 cervical cancer (n = 215) who under...
Article
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In 2015, fourteen topics were selected as major research advances in gynecologic oncology. For ovarian cancer, high-level evidence for annual screening with multimodal strategy which could reduce ovarian cancer deaths was reported. The best preventive strategies with current status of evidence level were also summarized. Final report of chemotherap...
Article
Objective: To identify risk factors for lower extremity lymphedema (LEL) using computed tomographic (CT) scan in patients undergoing lymphadenectomy for gynecologic cancers. Methods: We retrospectively reviewed 511 consecutive gynecologic cancer patients undergoing lymphadenectomy. Mean difference (3.77±3.14mm) of subcutaneous layer thicknesses...

Citations

... The reason for this may be that full-time workers have more day time activities. However, even the rate of the Pap test in women's work shifts (57.8%) is not inferior to that of the general population (54.8% in 2020 reported by Statistics Korea), and their rate of HPV vaccine uptake (39.9%) is higher than that of the general population (14.2%) [24]. We must exercise caution while interpreting this result because the working pattern of nurses usually fluctuates in the short term. ...
... Of the articles included, 25 addressed the lack of education of nongenetic health professionals on various important topics in clinical genetics (Nippert et al., 2014;Harding et al., 2019;Hallowell et al., 2019;Amara et al., 2016;Bensend et al., 2014;Bell et al., 2015;Arora et al., 2017;Carroll et al., 2016;Chowdhury et al., 2015;Cornel and van El, 2017;Dekanek et al., 2020;Delikurt et al., 2015;Medendorp et al., 2021;Bellhouse et al., 2021;Cox et al., 2012;Demmer and Waggoner, 2014;Hamilton et al., 2017;Klitzman et al., 2013;Mahon and Crecelius, 2013;Nair et al., 2017;Novinson et al., 2019;Prochniak et al., 2012;Talwar et al., 2016;Vadaparampil et al., 2015;White et al., 2020), 15 the concerns and avenues regarding trajectory and continuity of care (O'Shea et al., 2020;Harding et al., 2019;Hallowell et al., 2019;Amara et al., 2016;Derbez et al., 2021;Carroll et al., 2016;Mahon and Crecelius, 2013;Prochniak et al., 2012;Agnese and Pollock, 2016;Armstrong, 2020;Battista et al., 2011;Boitano et al., 2019;Douma et al., 2019;Kim et al., 2021;Sheppard et al., 2013), 12 the psychological and emotional impact of genetic testing and communication risks (Bensend et al., 2014;Arora et al., 2017;Chowdhury et al., 2015;Dekanek et al., 2020;Douma et al., 2016;Medendorp et al., 2021;Vadaparampil et al., 2015;Mikat-Stevens et al., 2015;Powers et al., 2017;Schroeder and Conroy, 2015;Shilling et al., 2020), and 16 the adherence to best-practice guidelines of various non-genetic health professionals providing genetic services (Bell et al., 2015;Cragun et al., 2015;Hamilton et al., 2017;Klitzman et al., 2013;Mahon and Crecelius, 2013;Vadaparampil et al., 2015;White et al., 2020;Agnese and Pollock, 2016;Armstrong, 2020;Douma et al., 2019;Sheppard et al., 2013;Beitsch and Whitworth, 2014;Cragun et al., 2016;Hull et al., 2018;Cragun and Pal, 2013;Lu and Spigelman, 2019). Other ethical issues addressed included confidentiality, disclosure, and fear of genetic discrimination (n = 10) (Klitzman et al., 2013;White et al., 2020;Agnese and Pollock, 2016;Mikat-Stevens et al., 2015;Powers et al., 2017;Schroeder and Conroy, 2015;Brooks et al., 2021;Pasquier et al., 2021;Devon et al., 2015), complexity of genetic test results (including variants of uncertain significance) (n = 8) (Arora et al., 2017;Hamilton et al., 2017;Mahon and Crecelius, 2013;Agnese and Pollock, 2016;Powers et al., 2017;Cragun et al., 2016;Brooks et al., 2021;Pasquier et al., 2021), consent (n = 8) (Bensend et al., 2014;Cragun et al., 2015;Hamilton et al., 2017;Vadaparampil et al., 2015;Beitsch and Whitworth, 2014;Pasquier et al., 2021;Devon et al., 2015;Scheinberg et al., 2020), and medical mismanagement (n = 5) (Amara et al., 2016;Bensend et al., 2014;Carroll et al., 2016;Dekanek et al., 2020;Scheinberg et al., 2020). ...
... These effects has been sufficiently severe that some consider the screening programs for this disease to be in a state of crisis [8][9][10]. Other studies have also shown an increasing number of women diagnosed with premalignant lesions [11][12][13]. Although many reasons may explain these negative effects, the decreased number of patients undergoing screening may be part of the problem [10,[14][15][16]. ...
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