Mingxing Huang's research while affiliated with The Third People's Hospital and other places

... The diversity of T cells, which play an important role in viral elimination (Kumar et al., 2018), gradually decreases and shows a sharp decline after age 40 years (Simnica et al., 2019). One study showed that in patients with Omicron, younger people had higher levels of neutralizing antibodies (Liang et al., 2022). These differences may allow faster and more efficient viral clearing in younger patients, without significantly affecting the immune system, so that their lymphocyte counts remain within the normal range; this is supported by evidence that clinical symptoms among younger patients are relatively mild compared with those of older adults (Davies et al., 2020). ...

... Additionally, AgNPs extracted from T. quadrivalvis have shown strong antiviral activity against various respiratory viruses such as Influenza A and human respiratory syncytial virus. The combination of AgNPs and macrolides can potentially be used in treating respiratory tract infections induced by these viruses, providing a new approach to the treatment of these infections [51]. ...

... Hepatocellular carcinoma (HCC) is one of the most common malignancy in China, accounting for 75-85% of liver cancer [1], which is associated to chronic hepatitis B infection (about 80%) [2,3]. Surgery is the most effective treatment for HCC. ...

... Asian countries near Vietnam, such as China and Korea have all recorded the presence of C. burnetii; the study by Huang et al (16) recorded an outbreak of a C. burnetii infection in a city in China (16). The study by Bae et al (17) conducted in Korea, recorded 8/40 cases of C. burnetii negative blood culture endocarditis using PCR analysis (17). ...

... consequences. However, several clinical trials that assessed the safety and efficacy of CQ administration in COVID-19 patients concluded in controversial results [42]. In light of our results, one might speculate that the blood compartment in association with this drug might have been disregarded. ...

... Several studies have shown that Aeromonas spp. intrinsically carry various bla OXA genes in their genomes that include the bla OXA-12 gene (Dubey et al., 2022a,b) previously detected in A. media, A. jandaei, A. sobria, A. dhakensis, and A. hydrophila (Rasmussen et al., 1994;Alksne and Rasmussen, 1997;Hilt et al., 2020;Huang et al., 2020;Dubey et al., 2022a) being in line with its presence in strain Ah5S-24 while bla FOX-7 previously reported in A. media and Phylogenetic tree comparing the tet(E) gene from different bacteria species. Note that the tet(E) Aeromonas veronii strain AhS5-24 had 100% similarity with tet(E) genes from other bacteria species that include Aeromonas caviae (BBR12376.1, ...

... Their data showed that patients with NAFLD showed a worse BMD status than those without NAFLD. The incidence rates of osteopenia (42.86% versus 25.93%) and osteoporosis (17.14% versus 3.70%) were significantly higher in PLWHIV with NAFLD than in those without NAFLD, and the odds ratio (OR) for patients with NAFLD exhibiting a worse BMD status compared with those without NAFLD was 4.49 (95% confidence interval (CI) 1.42, 14.15) [68]. Therefore, further research is needed to establish a link between all of these metabolic changes and the risk of osteoporosis in PLWHIV. ...

... In precise, CQ is extensively used as immunomodulator with anti-malarial activity [74][75][76][77][78]. Recently, an in vitro study revealed that, SARS-CoV-2 growth was found to be inhibited by CQ and these results have been reinforced by clinical trials on approximately 100 patients infected by SARS-CoV-2 [56,57,79,80]. In addition, it is more toxic than HCQ [54,55] and an overdose of CQ can be the reason of acute poisoning and death [81]. ...

... Due to the antimicrobial nature of bile, it was previously thought that the biliary tract is sterile in nature. However, recent evidences have suggested the existence of the biliary microbiome which is more diverse than the intestinal microbiome [144,145]. ...

... 15 Similar secondary infection rates have been reported in China. 16 It could be argued that the subjects of these research were not home-isolating at the time of the secondary infection within their household, but it does not undermine the fact that at least 60-70% of transmission was within households; 10 times more than any other single route. 17 Since home-isolation is solely hinged on the personal compliance of an individual, therefore it inevitably could lead to increased transmission. ...