Michael K Boit's research while affiliated with Kenyatta University and other places

Publications (32)

Article
Objectives: We aimed to determine the associations of non-alcoholic fatty liver disease (NAFLD) with cardio-metabolic risk factors for diabetes in adult Kenyans. Methods: A cross-sectional study was undertaken among rural and urban Kenyans of different ethnic origin. Ultrasonography scanning (USS) methods were used for the assessment of hepatic...
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Background Abdominal obesity predict metabolic syndrome parameters at low levels of waist circumference (WC) in Africans. At the same time, the African lipid profile phenotype of low high-density lipoprotein (HDL) cholesterol without concomitant elevated triglyceride levels renders high triglyceride levels detrimental to cardiometabolic health unsu...
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Objectives Physical activity is beneficial for metabolic health but the extent to which this may differ by ethnicity is still unclear. Here, the objective was to characterize the association between physical activity energy expenditure (PAEE) and cardiometabolic risk among the Luo, Kamba, and Maasai ethnic groups of rural Kenya. Methods In a cross...
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This paper reports findings from a study of the role played by high-profile Kenyan runners in the organization of Run-for-Peace events that took place in response to election-related violence in Kenya in late 2007 and early 2008. Acknowledging concerns expressed by some sociologists of sport about the role of celebrity athletes in the sport for dev...
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The relationship between metabolic disease and the non-modifiable risk factors sex, age and ethnicity in Africans is not well-established. This study aimed to describe sex, age and ethnicity differences in blood pressure (BP) and lipid status in rural Kenyans. A cross-sectional study was undertaken among rural Kenyans. BP and pulse rate (PR) were m...
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Women participating in endurance sports are at risk of presenting with low energy availability (EA), menstrual dysfunction (MD), and low bone mineral density (BMD), collectively termed the female athlete triad (FAT or TRIAD). Therefore, the purpose of the study was to determine the profile of the TRIAD among elite Kenyan female athletes and among n...
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The purpose of this study was to determine arterial blood gases, the mechanical limits for generating expiratory flow and the work performed by the respiratory muscles during treadmill exercise in Kenyan runners. Kenyan runners (10M, 4F; 25.2±1.3 yrs) were instrumented with a radial artery catheter; an esophageal balloon-tipped catheter and esophag...
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Low energy availability (EA) has been recognized as an instigator of menstrual dysfunction and subsequent hypoestrogenism that leads to deterioration in bone health. Elite Kenyan male athletes have been reported to often function under low energy balance. Therefore, the purpose of this study was to determine EA and menstrual function (MF) among eli...
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Little is known about the pathophysiology of diabetes in Africans. Thus, we assessed whether insulin resistance and beta-cell function differed by ethnicity in Kenya and whether differences were modified by abdominal fat distribution. A cross-sectional study in 1,087 rural Luo (n = 361), Kamba (n = 378), and Maasai (n = 348) was conducted. All part...
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Although habitual physical activity energy expenditure (PAEE) and cardio-respiratory fitness (CRF) are now well-established determinants of metabolic disease, there is scarcity of such data from Africa. The aim of this study was to describe objectively measured PAEE and CRF in different ethnic populations of rural Kenya. A cross-sectional study was...
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Aim: The aim of this study was to determine the association between different anthropometric parameters and metabolic profile in an overweight, adult, black Kenyan population. Methods: An opportunity sample of 245 overweight adult Kenyans (body mass index (BMI) ≥ 25 kg/m(2)) was analysed. A score of metabolic profile (metabolic Z-score) was cons...
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Comparable data to examine the physical activity (PA) transition in African countries such as Kenya are lacking. We assessed PA levels from urban (UKEN) and rural (RKEN) environments to examine any evidence of a PA transition. Nine- to twelve-year-old children participated in the study: n = 96 and n = 73 children from UKEN and RKEN, respectively. P...
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This study was designed to gather anthropometric and fitness-related data on Kenyan children living in urban (UKEN) and rural (RKEN) environments and to compare them with previous data collected on Canadian children in order to examine the potential nutrition-physical activity transition. Height, weight, waist circumference, triceps skinfolds were...
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To compare dietary patterns and food and macronutrient intakes among adults in three ethnic groups in rural Kenya. In the present cross-sectional study, dietary intake was estimated in adult volunteers using two non-consecutive interactive 24 h recalls. Dietary patterns were assessed from the number of meals and snacks per day and from the food ite...
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Obesity is increasing rapidly in Africa, and may not be associated with the same changes in body composition among different ethnic groups in Africa. To assess abdominal visceral and subcutaneous fat thickness, prevalence of obesity, and differences in body composition in rural and urban Kenya. In a cross-sectional study carried out among Luo, Kamb...
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Amount and quality of dietary fat modifies glucose tolerance. Omega 3 Fatty Acids (n-3F A) are polyunsaturated fats, mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) found primarily in fish and they have a positive effect on glucose tolerance. To compare risk of type 2 diabetes mellitus (T2DM), as demonstrated thourough impaired gl...
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To assess the prevalence of glucose intolerance in rural and urban Kenyan populations and in different ethnic groups. Further, to identify associations between lifestyle risk factors and glucose intolerance. A cross-sectional study included an opportunity sample of Luo, Kamba, Maasai, and an ethnically mixed group from rural and urban Kenya. Diabet...
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To determine the frequency of the ACTN3 R577X polymorphism (functional R allele and nonfunctional X allele) in a variety of African populations and to examine its influence on the success of elite East African endurance runners and West African sprinters. The R577X polymorphism was genotyped in 198 Ethiopian controls and 76 elite Ethiopian enduranc...
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Kenyan athletes have dominated international distance running in recent years. Explanations for their success include favourable physiological characteristics, which could include favourable genetic endowment, and advantageous environmental conditions. The aim of this study was to compare the demographic characteristics of elite Kenyan runners with...
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Previous studies have found Kenyan endurance runners to be in negative energy balance during training and prior to competition. The aim of the present study was to assess energy balance in nine elite Kenyan endurance runners during heavy training. Energy intake and expenditure were determined over 7d using weighed dietary intake and doubly labelled...
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East African runners are continually successful in international distance running. The extent to which genetic factors influence this phenomenon is unknown. The insertion (I) rather than deletion (D) of a 287 bp fragment in the human angiotensin converting enzyme (ACE) gene is associated with lower circulating and tissue ACE activity and with endur...
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Full-text available
Previous studies have found Kenyan endurance runners to be in negative energy balance during training and prior to competition. The aim of the present study was to assess energy balance in nine elite Kenyan endurance runners during heavy training. Energy intake and expenditure were determined over 7 d using weighed dietary intake and doubly labelle...
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Full-text available
The food and macronutrient intake of elite Kenyan runners was compared to recommendations for endurance athletes. Estimated energy intake (EI: 2987 +/- 293 kcal; mean +/- standard deviation) was lower than energy expenditure (EE: 3605 +/- 119 kcal; P < 0.001) and body mass (BM: 58.9 +/- 2.7 kg vs. 58.3 +/- 2.6 kg; P < 0.001) was reduced over the 7-...
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Kenyan runners, and especially those originating from the Kalenjin tribe, have dominated international middle- and long-distance running for over 40 years, prompting significant interest in the factors contributing to their success. Proposed explanations have included environmental factors, psychological advantage and favourable physiological chara...

Citations

... Therefore, the true ratio of undiagnosed MAFLD might have been underestimated. Even accounting for disparities in diagnostic approaches, our results document a substantial increase in the prevalence of MAFLD or NAFLD, which is contradictory to the higher prevalence of MAFLD among urban than among rural residents that has been reported in other countries throughout the world [5,16,17]. ...
... p = 0.035). In another study, which was multi-ethnicity research conducted in Kenya [20] (n = 1084), PAEE was inversely correlated with cardiovascular risk and central adiposity. Adults with CP have been reported to have a higher prevalence of all chronic diseases, such as diabetes, asthma, hypertension, heart disease, and stroke, than adults without CP [21]. ...
... This observation was attributed to several factors, including diet-related changes in the composition of the gut microbiota, which in turn may influence the development of MAFLD. Male adults from Ghana and Kenya present a lower prevalence of an increased FLI and higher prevalence of T2DM than females [37,38]. The explanation for the observed sex-specific relationships between the FLI-as a proxy marker of NAFLD-and T2DM may lay in the FLI components. ...
... Going back to my conception of the link between festivalization as quasi-linguistic structure and capitalism as a deep structure at the start of the chapter, festivalization of capitalism and its furthering by powerful elected and non-elected elites explains an important foundation of 'the epochal shift from a semantic of allocational struggles to valorization struggles' (Berthold Vogel in Soziopolis, 2017. The relationship between allocation and valorization can be demonstrated with what Rojek calls a 'gesturing economy' (see Chapter 11) and 'philanthropic hero' productions (see also Wilson et al., 2015). The matter's depth and the inclusion of middle classes into this phenomenon can be illustrated perhaps more succinctly with one of the many occurrences in the world of philanthropic giving-a story picked from the Internet news on professional sports, an entertainment industry in today's experience economy: ...
... Traditionally, Kalenjin people subsist on some combination of small-scale farming and pastoralism, and many people are habitually barefoot. The Kalenjin famously include many of the world's top competitive middle-and long-distance runners (Pitsiladis et al. 2004;Onywera et al. 2006). Running has long been part of Kalenjin culture, owing to the need to run to carry out cattle raids, which is an important custom among some pastoralist groups in East Africa that typically requires running long distances, sometimes well beyond the distance of a marathon (Bale & Sang, 1996;Christensen & Damkjaer, 2010). ...
... e reason for higher Hgb in AG than AAA may be due to AG were more sweaters than others since living and training at a high altitude (3100 m) may induce perspiration and urination more than AAA. e mean Hgb of male athlete runners was higher than other male professional Ethiopian runners, elite male Kenyan distance runners, Eritrean endurance runners, and Southern Ethiopian soccer players [41,45,47,49,[51][52][53]. e observed difference can be ascribed to differences in the rate of sweating, altitude (3100 m above SL), level of athletes, and plasma volume expansion. ...
... Most of Kenya's world-class athletes were born, raised and continue to train in high altitude areas of mainly the Rift Valley province [1]. Several studies have been conducted in an effort to explain and better understand the factors behind the success of elite Kenyan distance runners [2][3][4][5]. A number of explanations have been put forward as being partly responsible for the Kenyan athletics phenomenon, including genetic predisposition, physiological advantage, nutrition and socio-environmental factors. ...
... En las primeras investigaciones, la relación entre el genotipo funcional del ACTN3 (RX y especialmente RR) y el rendimiento en deportes de potencia y velocidad parecía estar clara (Yang et al., 2003). Sin embargo, hoy en día existe cierta controversia (McCauley, Mastana, Hossack, Macdonald y Folland, 2009;McCauley, Mastana y Folland, 2010;Rodríguez-Romo et al., 2010;Hanson, Ludlow, Sheaff, Park y Roth, 2010;Massida et al., 2012), que es aún mayor cuando tratamos de asociar dicho genotipo a deportes de resistencia (Yang et al., 2005;Saunders et al., 2007;MacArthur et al., 2007;Ma et al., 2013). Otro aspecto a tener en cuenta es el perfil de la muestra utilizada en los estudios mencionados, siendo de máximo nivel competitivo (mundialistas u olímpicos) en aquellos que obtuvieron una correlación positiva con el rendimiento (Yang et al., 2003;Scott et al., 2010). ...
... For example, a study in rural Kenya found 32% higher insulin resistance among Maasai compared with the Luo and 17% higher compared with the Kamba. 3 African populations are exposed to a wide range of environmental exposures and lifestyle factors that can affect insulin sensitivity and beta-cell function. Lifestyle factors such as dietary intake, physical activity, alcohol consumption, and smoking differ greatly between population groups within Africa and between Africans in Africa and African migrants in Europe and the USA. ...
... In addition to high rates of elevated BMI, the study also established a high prevalence of central obesity as indicated by abnormal waist circumference [35%]. This has significance as abdominal obesity is believed to have the highest impact on metabolic profile amongst Africans [37]. These findings indicate the need to screen for obesity, and the need to put interventions in place to lower these rates in order to promote cardiovascular health in LMIC settings. ...