Michael F. Slag’s scientific contributions

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Publications (1)


Impotence in Medical Clinic Outpatients
  • Article

April 1983

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11 Reads

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209 Citations

JAMA The Journal of the American Medical Association

Michael F. Slag

One thousand one hundred eighty men in a medical outpatient clinic were screened as to the presence of impotence. Four hundred one men (34%) were impotent, and of those, 188 (47%) chose to be examined for their problem. After a comprehensive evaluation the following diagnoses were obtained: medication effect, 25%; psychogenic, 14%; neurological, 7%; urologic, 6%; primary hypogonadism, 10%; secondary hypogonadism, 9%; diabetes mellitus, 9%; hypothyroidism, 5%; hyperthyroidism, 1%; hyperprolactinemia, 4%; miscellaneous, 4%; and unknown causes, 7%. The mean age of the impotent patients was 59.4 years, and the prevalence of alcoholism was 7%. Luteinizing hormone, follicle-stimulating hormone, testosterone, thyroxine, triiodothyronine (T3), T3 resin uptake, and prolactin studies were necessary to diagnose individual cases. We conclude that erectile dysfunction is a common and often overlooked problem in middle-aged men followed in a medical clinic. (JAMA 1983;249:1736-1740)

Citations (1)


... phosphodiesterase type 5 or PDE 5 inhibitors such as sildenafil), the following section will review those medications that have been shown to have a negative effect on erectile functioning. Men taking antihypertensive medications often report erectile dysfunction; a result that has been found in both the retrospective studies (Hogan, Wallin, & Baer, 1980;Reichgott, 1979;Slag et al., 1983) and prospective trials (Croog, Levine, Sudilovsky, Baume, & Clive, 1988;Kostis et al., 1990;Rosen, Kostis, Jekelis, & Taska, 1994;Suzuki, Tominaga, Kumagai, & Sarita, 1988), although at least one study found no adverse effects of these medications on sexual function (Broekman, Haensel, van de Ven, & Slob, 1992). Antihyperlipidemics (medications used to treat hypercholesterolemia or high cholesterol), have also been shown to reduce erectile functioning (Francis, Kusek, Nyberg, & Eggers, 2007), and there is some indication that acetylcholine-induced relaxation associated with the medical treatment of diabetes mellitus may also contribute to erectile dysfunction (Meston & Frohlich, 2000). ...

Reference:

The effects of common medications on volumetric phallometry
Impotence in Medical Clinic Outpatients
  • Citing Article
  • April 1983

JAMA The Journal of the American Medical Association