August 1967
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141 Citations
Archives of Biochemistry and Biophysics
Ageing and dealkylation of Soman-inactivated electric eel cholinesterase occur at essentially identical rates and are catalyzed by an acidic group in the enzyme with a pKa′ of 6.4. Dealkylation of Soman-inactivated electric eel cholinesterase takes place by a carbonium ion mechanism with the production of 2,3-dimethyl-2-butanol; 2,3-dimethyl-1-butene; and 2,3-dimethyl-2-butene.