Mario Piattelli’s research while affiliated with University of Salerno and other places

... On the other hand, Candida Antarctica Lipase B (CAL-B) was found to be a highly active biocatalyst for the direct acylation of compound 1 with vinyl acetate and propanoate as acyl donors affording compounds 16, 17 and 18 (Fig. 5) (Nicolosi et al., 1993;Miyazawa et al., 2008). Additionally, Rajakumar and coworkers reported the synthesis of cyclophane diamide 20 by the reaction of quinacetophenone 1 with N,N 0 -(a,a 0 dichloroacetyl)-1,2-phenylenediamine 19 (Scheme 7) (Rajakumar et al., 2006). ...

Reference:

Quinacetophenone: A simple precursor to privileged organic motifs

... [19] Liquid-liquid extraction studies have demonstrated the separation ability of B 4 bL 4 and B 6 bL 6 for the lighter actinides, as compared to Ln III ions, and the calix [6]arene receptor revealed to be the best extractant. [20] Owing to the large dimension of their annulus, calix [8]arenes are promising receptors both for medium-sized organic compounds [21] and large metal cations; for instance, they can encapsulate up to two Ln III ions in the same molecular edifice. [13,22] For p-substituted calix [8]arenes, the 1:1 versus 2:1 stoichiometry is simply tuned by the strength of the base used to deprotonate the hydroxy groups. ...

Reference:

Lanthanide Complexes with a Calix[8]arene Bearing Phosphinoyl Pendant Arms

... Compound 9 is a monoacylglycerol already characterized from the marine brown alga Ishige sinicola (Hirao et al. 2012). Compound 10 [sn-3-O -(geranylgeranyl)glycerol] was first isolated from Dilophus fasciola [currently regarded as D. fasciola (Amico et al. 1977)] and after that from the dictyotacean brown alga Taonia lacheana (Tringali et al. 1995). The main constituents of the crude extracts were not the same for the different samples A, B, and C. ...

Reference:

Anti-microfouling properties of compounds isolated from several Mediterranean Dictyota spp.

... Different alphabets denote a significant difference at p50.05 between different molar ratios of quercetin:oleic acid and origin of lipase. bionconversion yield obtained with CAL-B instead of PCL-C were not in agreement with the studies by Ardhaoui et al. (2004a), Lambusta et al. (1993), and Sakai et al. (1994) who found that aglycone flavonoid enzymatic modification was only possible with PCL-C but not CAL-B as only PCL-C was able to access to the phenolic groups on quercetin. In fact, most aglycon flavonoid modifications, such as catechin and quercetin, were catalyzed by PCL-C (Lambusta et al. 1993;Sakai et al. 1994;Chebil et al. 2007). ...

Reference:

Lipase-catalyzed acylation of quercetin with cinnamic acid

... Il apparait que, pour des substrats donnés, l'effet du solvant dépend de la nature de l'enzyme utilisée : subtilisine, lipase de Pseudomonas cepacia (PCL) ou CALB. En effet, les synthèses d'esters de flavonoïdes catalysées par la subtilisine sont généralement réalisées dans la pyridine (Danieli et al., 1989 ;Danieli et al., 1990), tandis que Lambusta et al. (1993) et (Riva et al., 1996;Kontogianni et al., 2003;. (Danieli et al., 1989;Lambusta et al., 1993;Enaud et al. , 2004;. ...

Reference:

Extraction, identification, caractérisation des activités biologiques de flavonoïdes de Nitraria retusa et synthèse de dérivés acylés de ces molécules par voie enzymatique

... On the other hand, Candida Antarctica Lipase B (CAL-B) was found to be a highly active biocatalyst for the direct acylation of compound 1 with vinyl acetate and propanoate as acyl donors affording compounds 16, 17 and 18 (Fig. 5) (Nicolosi et al., 1993; Miyazawa et al., 2008). Additionally, Rajakumar and coworkers reported the synthesis of cyclophane diamide 20 by the reaction of quinacetophenone 1 with N,N 0 -(a,a 0 dichloroacetyl)-1,2-phenylenediamine 19 (Scheme 7) (Rajakumar et al., 2006). ...

Reference:

Quinacetophenone: A simple precursor to privileged organic motifs

... The introduction of new hybrid is one of the most innovative developments in citrus field since the quality of products, such as juice and essential oil, is fundamental to promote the citrus industrial processing, several Authors studied the volatile fraction composition of new citrus hybrid essential oils [7][8][9][10] . ...

Reference:

Characteristics of a New Citrus Hybrid Essential Oil, Citrus clementina cv. Nules x Citrus limon cv. Cavone

... The monoterpenes were the main fraction of this essential oil (89.57%), divided into hydrocarbons form (1.11%) and oxygenates form (88.46%). This composition was broadly similar to the composition of Thymbra capitata essential oil from Italy which contains more than 86% of carvacrol 41 . Approximately the same results were found on other species like Origanum vulgare L. in which oxygenated monoterpenes were the main constituents (80.3%), following by monoterpene (16.9%) and sesquiterpene hydrocarbons (1.7%) 42 . ...

Reference:

Chemical Composition, Antioxidant and Antibacterial Activities of Essential Oil and Phytochemical Screening of Extracts of Aerial Parts of Thymus atlanticus

... The other general strategy described in this chapter is the one involving the introduction of intramolecular covalent bridges to limit the conformational flexibility of calix [8]arenes (Geraci et al., 1995). In this respect, the use of cesium salts has allowed the regioselective introduction of covalent bridges to the 1 and 5 phenolic positions of p-tert-butylcalix [8]arene (Cunsolo et al., 1994). The importance of 1,5-substitution (or 1,5-3,7 substitution) resides in the high symmetry of such derivatives, relative to 1,2-or 1,4-derivatives, which appears to result in better packing interactions. ...

Reference:

Calix[8]arenes Solid-State Structures: Derivatization and Crystallization Strategies

... The addition of molecular sieves had a dramatic effect on the reaction rate, by adsorbing the acetaldehyde that is released in the reaction. Nicolosi and co-workers prepared enantiopure ferrocenyl sulfides possessing planar chirality by means of lipase-assisted resolutions in 1996-1997 [22,23]. The first thing they noticed was that molecular sieves had beneficial effects on the reaction rate and a slight improvement in the selectivity factor, while the addition of water or ethylene glycol completely inhibited the reaction, concluding that the quantity of residual water in the reaction media had a strong influence on both the activity and the selectivity of the process. ...

Reference:

Kinetic Resolution: A Powerful Tool for the Synthesis of Planar-Chiral Ferrocenes