Marilena Koukounia’s research while affiliated with National and Kapodistrian University of Athens and other places


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Publications (1)


Direct Antibiotic Activity of Bacillibactin Broadens the Biocontrol Range of Bacillus amyloliquefaciens MBI600
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August 2021

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Siderophores have mostly been studied concerning their contribution to the fitness and virulence of bacterial pathogens. In the present work, we isolated and characterized for the first time the siderophore bacillibactin from a commercial bacterial biocontrol agent.

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Citations (1)


... Interestingly, B. velezensis MTUC2 inhibited the biofilm formation of A. baumannii Ab0013 and E. coli K-12 at lower CFS concentrations (0.78% and 6.25%), respectively, compared to B. subtilis MTUA2. These results, in line with previous studies, suggest that the antibiofilm effects of both strains may be attributed to the presence of three gene clusters involved in non-ribosomal synthesis of bacillaene, bacilysin and bacilibactin; these clusters have previously been shown to contribute to biofilm inhibition (Dimopoulou et al., 2021;Erega et al., 2021). Compared to B. velezensis MTUC2, B. subtills MTUA2 displayed stronger activity against A. baumannii achieving an MBIC 50 for both test strains. ...

Reference:

Investigating the antimicrobial and antibiofilm properties of marine halophilic Bacillus species against ESKAPE pathogens
Direct Antibiotic Activity of Bacillibactin Broadens the Biocontrol Range of Bacillus amyloliquefaciens MBI600