Maria Teresa Greco's research while affiliated with Mario Negri Institute for Pharmacological Research and other places

Publications (8)

Article
This living, systematic review aims to provide an updated summary of the available evidence on pain undertreatment prevalence in patients with cancer; correlations with some potential determinants and confounders were also carried out. We updated a systematic review published in 2014, including observational and experimental studies reporting the u...
Article
Full-text available
Background: Health technology assessment and ethical issues have to be dealt with in deciding on national carrier screening for cystic fibrosis (CF)-the most frequent severe autosomal recessive disease in Caucasian populations and several stakeholders need to be involved. A citizens' jury is one way to ask citizens to deliberate on controversial t...
Article
Full-text available
Background Opioids are the most important pharmacological treatment for moderate-to-severe cancer pain, but side effects limit their use. Transdermal fentanyl (TDF) and oral prolonged-release oxycodone-naloxone (OXN-PR) are effective in controlling chronic pain, with less constipation compared to other opioids. However, TDF and OXN-PR have never be...
Article
The study titled "Economic and financial sustainability of health services, equity, and quality of care: objectives pursued through a strategic alliance between health, research and citizenship" launched the project "Equity in Health", based on the idea that also social variables may affect the access to health care. A pilot study was conducted on...
Article
The study titled "Economic and financial sustainability of healthcare services, equity, and quality of care: objectives pursued through a strategic alliance between healthcare, research, and the general public" launched the project "Frailty- Vulnerability in Health", based on the hypothesis that social variables may also affect access to health car...

Citations

... 33,56 On the other hand, for decades already, frailty has been used as an operational tool for studying the relationship of disability related to aging 32 and psychosocial aspects of health inequality. 9 In addition to these concepts, other designations to particular conditions of vulnerability can be applied to subindividual dimensions of disease-health, such as alteration, debility and weakness, absent from the specialized literature. In this proposal, the term 'alteration' refers to modifications in the microstructure of organic units that, at the molecular and cell levels, lead an anomaly to become abnormal, or a defect. ...
... Under the medical care theme, the author encountered and analyzed a host of controversial topics including the availability of health screening and age restrictions, cystic fibrosis screening (Mosconi et al. 2018), controversial prostate-specific antigen screening (PSA; Rychetnik et al. 2014), controversial designer DNA testing for diseases in unborn babies (Iredale and Longley 2007), prioritization of immunization programs (Parrella et al. 2016), and mammography examinations of women between 70-74 years old (Degeling et al. 2018). For example, regarding PSA screenings, while there is a possibility of increasing the survival rate, there is also concern that unnecessary treatment of prostate cancer may increase the burden on the body (Rychetnik et al. 2014). ...
... Pain is one of the most experienced anxieties in cancer patients. Despite so many beliefs and fears about opioid use, old World Health Organization (WHO) publications¹ supported by recent international guidelines 2,3 for the pharmacological treatment of cancer pain in its moderate to severe stages, suggest that the use of opioids is the best therapy, evidencing the use of morphine 4 . Nevertheless, side effects such as opioid-induced constipation deserve highlighting 5,6 . ...