Maria E. Díaz-González de Ferris's research while affiliated with Microbiome Core Facility USA and other places

Publications (21)

Article
Objectives To evaluate national trends in healthcare transition (HCT) preparation over a four-year period using the National Survey of Children’s Health (NSCH). Our secondary aim was to identify and examine disparities in receipt of HCT preparation over the study period. Study Design Data from the NSCH, an annual serial cross-sectional survey from...
Article
Background: Adolescents and young adults (AYA) with chronic conditions should acquire self-management skills as part of their healthcare transition (HCT) from pediatric to adult-focused care. HCT/self-management skills have the potential to help mitigate health disparities among minority AYA with chronic conditions. This study investigated school n...
Article
Full-text available
Purpose of the Review Conditions typically prevalent in adults such as hypertension, kidney stones, osteoporosis, and chronic kidney disease are increasing among adolescents and young adults (AYA). The purpose of this review is to describe the association of these conditions to a high salt diet among pediatric patients. Recent Findings We present...
Article
Purpose We evaluated disease knowledge/self-management skills among low-income Mexican young adults maintained on dialysis and to test the effectiveness of the A.L.L. Y.O.U. N.E.E.D. I.S. L.O.V.E (AYNIL) Manual – Spanish Version on patient-reported outcomes. This is a low literacy teaching tool designed with patients and educators' input. Design a...
Article
Background Polyuria is a common problem in patients with tubular diseases, especially for those with CKD and high-output Fanconi syndrome. There are currently no guidelines on how to treat debilitating polyuria, in children or adults, and vasopressin is usually not effective.Case-diagnosis/treatmentA 13-year-old female with idiopathic Fanconi syndr...
Article
Preparation for health-care transition from paediatric to adult-focused care must continue in young adulthood and requires coordination and an inter-disciplinary approach; however, the implementation of available tools and interventions remains challenging worldwide. Current practices fail to address issues related to patient safety, mental health,...
Chapter
Determining the level of glomerular filtration is important for drug clearance, but it is challenging in the setting of developing kidneys, more so in those with acute kidney injury. Acute kidney injury (AKI) in children is a common problem and requires the attention of pediatric nephrologists. Typically, kidney function is measured by an estimate...
Article
Introduction: The number of medications could serve as a surrogate for burden of care at home and may affect health-related quality of life (HRQoL) in children with chronic kidney disease (CKD). Methods: Using baseline data from the Chronic Kidney Disease in Children (CKiD) Study, we modeled HRQoL scores, self-reported by the child (if ≥ 8 years...
Article
Background and Objective Children of Spanish-speaking caregivers face multiple barriers to care in academic medical centers. This study identified barriers and facilitators of health care and described use of health information technology in order to guide interventions and optimize services. Methods In-depth, audiotaped interviews were conducted...
Article
Aim Review of current knowledge on assessing renal function in term and preterm neonates. Methods Literature review and analysis of own data. Results Prematurity, genetic, environmental and maternal factors may alter peak nephron endowment and life‐long renal function. Nephrogenesis continues until 34‐36 weeks of gestation, but it is altered with...
Article
Background It remains unclear how transition readiness is associated with various domains of health in children and young adults. Our objective was to describe the transition readiness of children and young adults with inflammatory bowel disease (IBD) and examine its associations with demographic factors, IBD activity, and measures of physical, psy...
Article
Full-text available
Background: Most pediatric nephrologists work in academia. Mentor-mentee relationships provide support and guidance for successful research career. Mentorship program implementation is valuable in medical fields for providing research opportunities to young faculty. Methods: The American Society of Pediatric Nephrology (ASPN) established a research...
Article
Objective: We sought to assess worldwide differences among pediatric patients undergoing hemodialysis. Because practices differ widely regarding nutritional resources, treatment practice, and access to renal replacement therapy, investigators from the Pediatric Investigation and Close Collaboration to examine Ongoing Life Outcomes, the pediatric s...
Article
Full-text available
Background: While there is a great deal of research updating methods for estimating renal function, many of these methods are being developed in either adults with CKD or younger children. Currently, there is limited understanding of the agreement between the modified new bedside Schwartz estimated glomerular filtration rate (eGFR) formula and the...

Citations

... Since the homozygous SLC34A3 mutation (c.835_846+10del.T) in our patient resulted in reduced or non-functioning sodium phosphate cotransporter activity, which could lead to sodium wasting, we wanted to investigate the sodium levels in skin and muscle and performed a 23 Sodium MRI study. [12,13] The 23 Sodium MRI study took place while our patient was on sodium phosphate supplements, but before the addition of rhGH and Fluconazole. In contrast to our hypothesis about sodium wasting, the 23 Sodium MRI was normal and did not reveal evidence of reduced whole leg, skin or muscle sodium content, compared to healthy age-matched controls ( Figure 3). ...
... Since the homozygous SLC34A3 mutation (c.835_846+10del.T) in our patient resulted in reduced or non-functioning sodium phosphate cotransporter activity, which could lead to sodium wasting, we wanted to investigate the sodium levels in skin and muscle and performed a 23 Sodium MRI study. [12,13] The 23 Sodium MRI study took place while our patient was on sodium phosphate supplements, but before the addition of rhGH and Fluconazole. In contrast to our hypothesis about sodium wasting, the 23 Sodium MRI was normal and did not reveal evidence of reduced whole leg, skin or muscle sodium content, compared to healthy age-matched controls ( Figure 3). ...
... It is also important to be aware of the impact immunosuppressive treatment may have, with the potential to aggravate cardiovascular disease also in young kidney transplanted patients [16]. A well-planned and carefully executed transition phase from paediatric to adult medical care needs to be present in all renal units to avoid problems with compliance and additional aggravation of the medical condition [17]. ...
... For children and adolescents with epilepsy, it has been shown that the seizure burden is only associated with a lower HRQOL at a later age, presumably because social interaction and independence become more important in the hierarchy of needs [19]. A similar observation was made in children and adolescents with chronic kidney disease, where HRQOL appears to be significantly reduced in end-stage renal disease regardless of age [48,49]. In adults with TSC chronic kidney disease is associated with lower HRQOL [50]. ...
... This finding is like the study by Chandra et al. (22) which demonstrated that Hispanic children were less likely to be provided with an asthma action plan at discharge, potentially due to a language barrier. Similarly, as demonstrated in studies by Flores and Flower, children who come from households where English is not the primary language experience multiple disparities in medical and oral health, access to care and use of services (24,25). Our hospital system is already equipped with 24-h interpreter services, though it is unclear from our data how often this resource is utilized for non-English speakers. ...
... Apart from the need for calibrated reference materials, new methodologies may have to be utilized to improve the lower limit of detection, and there may be a need to measure creatinine with novel methods necessary for precision at the lower limit of detection [12]. This is especially true in the most vulnerable population, prematurely born and term infants, who require accurate assessment of kidney function [13], not only for the diagnosis of acute kidney injury, but also for proper drug dosing of the over 60% renally excreted drugs [14]. ...
... 8,9 It has been shown to have good internal reliability and criterion validity in youth with chronic conditions ages 14 to 26, 9 though it has not been validated in youth with IBD specifically. It has been used extensively in research settings [10][11][12][13][14][15][16][17][18][19][20] including in studies involving youth down to age 12 years [14][15][16] and in studies focused on youth with IBD. 12,15,[17][18][19] Its use in the clinical setting has been limited by the lack of a clear association between TRAQ-20 scores and health outcomes, and therefore a lack of a clear score-based indication for when a young person can be deemed adequately prepared to transfer to adult-centered health care. ...
... leadership roles. The development of membership programs represents an option to provide support and guidance for successful careers, [6] with positive effects on capacity building for mentees. [7] Of the different types of programs, remote mentorship has previously been shown to be effective [8] and can improve access in underrepresented groups [9] and reduce gender inequalities. ...
... AYAs with CKD/ESKD have unique comorbidities ( Fig. 1; Table 1) that create specific challenges for patients, families, and providers as they have to manage the burden of care including: polypharmacy [10], procedures (enteral feeding, catheterizations, injections -growth hormone -or erythropoietin-stimulating agents -or dialysis), special diets, academic challenges, multiple medical appointments, and increase health-care utilization (surgeries, admissions, or emergency department visits) [11]. Other comorbidities include cardiovascular complications [12,13], growth, mineral bone disorders [14], anemia, reproductive abnormalities, and dental conditions. These patients need close interdisciplinary collaboration to optimize their care. ...
... 1 The 2009 Chronic Kidney Diseases Epidemiology Collaboration (CKD-EPI) creatinine equation does not seem to perform as well in adolescents and young adults (AYA). 2 In 2021 Pierce et al 3 developed eGFR equations ("U25 equations") using either cystatin C or serum creatinine for children/AYA up to 25 years old with mild-to-moderate chronic kidney disease enrolled in the CKiD study. This prospectively assembled North American cohort included 22% non-Hispanic Black participants. ...