Margret M. Baltes’s research while affiliated with Technische Universität Berlin and other places

The purpose of this study was to investigate the relationships among major life events, chronic events, daily instrumental activities, and well-being. Fifty individuals between 73 and 93 years of age reported major life events, minor hassles and uplifts, and daily activities during 5 measurement periods. In addition, positive affect was assessed in situ 5 times per day on 6 consecutive days on the basis of a random time-sampling scheme. The effects of major life events on positive affect were transmitted through minor events. However, there was no evidence that the relationship between minor events and positive affect was moderated by the occurrence of a major event. The relationship between life events and positive affect, however, was moderated by change in instrumental activities.

The purpose of this study was to investigate the relationships among major life events, chronic events, daily instrumental activities, and well-being. Fifty individuals between 73 and 93 years of age reported major life events, minor hassles and uplifts, and daily activities during 5 measurement periods. In addition, positive affect was assessed in situ 5 times per day on 6 consecutive days on the basis of a random time-sampling scheme. The effects of major life events on positive affect were transmitted through minor events. How-ever, there was no evidence that the relationship between minor events and positive affect was moderated by the occurrence of a major event. The re-lationship between life events and positive affect, however, was moderated by change in instrumental activities. In late life, the majority of life experiences seem to be adverse: social losses, illness events, changes in roles, and shifts in patterns of daily events (Zautra, Affleck, & Tennen, 1994). Researchers have interpreted evidence accumulated since the 1960s to suggest that individuals exposed to adverse life events are at greater risk for the onset of distress and illness (Turner & for assistance in data collection and Franziska Perels and Sigrun Wü rfel for their help with data coding. Moreover, we are grateful to our Berlin Aging Study colleagues for their coop-eration, and last, many thanks to our participants for contributing time and energy to this demanding study.

Although much of the research done by social gerontologists focuses on the decline and loss associated with old age, many older people experience the last stage in life as a satisfying and productive time in life. Especially as the demographics of the world’s population change in future decades, it becomes increasingly important to understand the behavioral, cognitive, and motivational processes involved in optimal aging. This chapter—which draws heavily on an earlier article by Baltes and Carstensen (1996)— considers the historical, societal, and philosophical influences that have directed attention away from successful aging and offers the metamodel of selective optimization with compensation (SOC) (Baltes & Baltes, 1990) as a framework for studying adaptive aging. The process of selection—namely, narrowing the array of goals and domains to which resources are directed—is considered to be the cardinal principle of lifespan development and is discussed generally in terms of selective optimization with compensation and specifically within the realm of social behavior in terms of socioemotional selectivity theory (Carstensen, 1993,1998; Carstensen, Isaacowitz, & Charles, 1999).

This article examines gender differences in social relations and resource deficits in France (N= 553), Germany (N= 516), Japan (N= 491), and the United States (N= 514). These data, from regionally representative samples, indicate few gender differences in quantity or quality of social relations, but that women are more likely than men to experience widowhood, illness, and financial strain. In all countries, more deficits and more negative social interactions are associated with higher levels of depressive symptoms. Interestingly, among women in France and Japan but not among men in any country, quality of social relations offsets the negative consequences of resource deficits. Findings suggest that quality of social relations may have important implications for helping people, particularly women, cope with resource deficits common in late life.

Previous cross-sectional research has shown that older people who are rich in sensorimotor-cognitive and social-personality resources are better functioning in everyday life and exhibit fewer negative age differences than resource-poor adults. Longitudinal data from the Berlin Aging Study was used to examine these findings across a 4-year time interval and to compare cross-sectional indicators of adaptive everyday functioning among survivors and nonsurvivors. Apart from their higher survival rate, resource-rich older people (a) invest more social time with their family members, (b) reduce the diversity of activities within the most salient leisure domain, (c) sleep more often and longer during daytime, and (d) increase the variability of time investments across activities after 4 years. Overall, findings suggest a greater use of selection, compensation, and optimization strategies in everyday functioning among resource-rich older adults as compared with resource-poor older adults.

This study results from an effort to examine the relationship between the diagnostic potentials for detecting risk status for dementia of a cognitive plasticity approach and a traditional status-oriented procedure (test battery) by Storandt et al. [Arch Neurol 1984;41:497-499]. The aim is to compare prediction accuracy for risk for developing dementia with these two approaches. A sample of 106 community-dwelling elderly adults were tested with both procedures, and their scores on the Structured Interview for the Diagnosis of Dementia used as external criterion for predicting risk status. The findings show that figural relations pretest and training gains account for a considerable amount of individual differences in mental status similar to that explained by the traditional test battery. In addition, the accuracy of discrimination between healthy and at-risk participants appears slightly higher when using the figural pretest and training gains. These results suggest the conclusion that use of figural relations tests and the cognitive plasticity approach represents a viable alternative to the traditional, status-oriented test battery as a means of early diagnosis of dementia in nonclinical populations.

This study examined social network characteristics of adults aged 70 to 90 years in relation to widowhood and illness in France, Germany, Japan, and the United States. Participants were drawn from representative samples from each of the 4 countries (total N = 1,331). Resource deficit profiles based on whether respondents were widowed, ill, both, or neither were directly related to social network characteristics for German and Japanese adults, were differentially related by gender and age for French adults, and were not related to social networks of Americans. Country, gender, and age differences in total network size, proportion of close network members, and frequency of contact with network members are reported. Similarities and differences found in the associations between normative late-life deficits and social network characteristics in the 4 countries point to the importance of investigating sociocultural factors that mediate the impact of resource loss and afford life quality in very old age.

In rotogravure industry, contributing considerably to mass color printing of catalogues and magazines, toluene is still extensively used as paint solvent, and many printers have been exposed to this chemical for several decades. Information on adverse health effects associated with long-term toluene exposure is still controversial. In a multi-center study, adverse health effects possibly associated with long-term toluene exposure were evaluated. In 12 rotogravure factories, 1226 male volunteers were recruited, and sufficient information on exposure and on medical data was compiled for about 1077 of them. Evaluations included: physical examination, standard tests of psycho-physiological and psycho-motoric performances, self-report of subjective symptoms, and data on a variety of laboratory blood tests. The medical data were correlated with the length (months) of toluene exposure, and a rough estimate of the extent of exposure (i.e. highly exposed printers and their helpers versus employees working at locations with low or negligible toluene exposure). A small reference group (n=109) was selected from companies of the paper industry. When linear regression curves were calculated (test results versus duration of exposure), extremely low overall coefficients of determination (r(2) adj.) of a few percent were estimated within the data clouds, with sometimes statistically significant P-values. Closer analyses revealed a strong influence of the confounding factor age, no clustering of abnormal values of highly toluene-exposed volunteers, and the vast majority or all values of the highly and long-term toluene-exposed participants staying within the reference ranges. Thus, no medical relevance of P-values <0.05 could be recognized in this evaluation, and there may have been some border-line deviations or results largely occurring by chance in the large trial. In a small cluster of the many rotogravure printers toluene-exposed for more than 20 years, the highest systolic blood pressure values of the study were found, but many possible confounding factors were not taken into account. Data on acute exposure and possible effects are presented in accompanying papers (Neubert et al., 2001a, Neubert et al., 2001b). Restricting the conclusions to the end points evaluated as well as the apparent limitations of the evaluation, no evidence was found that long-term occupational toluene exposure extending over several decades in the rotogravure industry in the Western part of Germany was convincingly associated with chronic adverse health effects or convincingly altered surrogate markers in still working male volunteers. Several peculiarities and pitfalls arising when interpreting medical data associated with such a type of environmental exposure must be considered. Reversibility of alterations previously induced at higher levels of toluene-exposure, as well as a healthy workers effect, cannot be excluded for some of the medical end points evaluated.

Data on possible acute effects of today's relevant low-level exposure to toluene are contradictory, and information on possible effects of exposure under occupational conditions is largely lacking. In a controlled, multi-center, blinded field trial, effects possibly associated with acute toluene exposure were evaluated in workers of 12 German rotogravure factories. Medical examinations (inquiries on subjective symptoms, and standard tests of psycho-physiological and psycho-motor functions) were performed on almost 1500 volunteers, of whom 1290 were toluene-exposed (1178 men and 112 women), and about 200 participants served as references (157 men and 37 women), but the main aim of the trial was to reveal dose-response relationships. All volunteers were of the morning work-shift (6 h exposure). Both individual ambient air concentrations (time-weighted average) during the work-shift, as well as blood toluene concentrations after the work-shift were measured. Therefore, the medical data could for the first time be correlated with the actual individual body burden (blood toluene level) at the time of testing. In order to largely exclude confounding by chronic toluene exposure, kinetic measurements as well as the psycho-physiological and psycho-motoric tests were performed before and after the work-shift. Except for minor statistical deviations, neither convincing dose-dependent acute effects could be demonstrated with regression analyses in male volunteers at the exposure levels evaluated, nor were significant differences found when applying group statistics (highly toluene-exposed group versus volunteers with negligible exposure). Due to the rather large number of participants, the predictive power of the study is high, especially when compared with previous publications. In two psycho-physiological tests, a few more female volunteers with quite low toluene body burdens (<340 microg/l blood) showed relatively low scores when compared with participants of the reference group. Although evidence for a medical relevance is meager, the small numbers of participants, in both the exposure and the reference groups, hamper a reliable interpretation of the results concerning exposure levels above 85 microg toluene/l blood, and it is difficult to take confounding factors adequately into account. For the end points evaluated and under occupational conditions, neither blood toluene levels of 850 to 1700 microg/l (in the highest exposure group [EXPO-IV] with 56 participants), as measured 1/2 (+/-1/2) h after the work-shift, nor ambient air concentrations (time-weighted average over 6 h) between 50 and 100 ppm (188-375 mg/m(3)) were convincingly associated with alterations in psycho-physiological and psycho-motoric performances or increased the frequency of subjective complaints in male volunteers. For higher dose ranges of toluene exposure (i.e. >1700 microg toluene/l blood [or >100 ppm in ambient air]), our data set is too small for far reaching conclusions. Our data are insufficient for conclusions on a possibly higher susceptibility to toluene of some female workers. Results of kinetic studies and possible effects of long-term exposure are discussed in two accompanying publications (Neubert et al., 2001; Gericke et al., 2001).