Margie E. Lachman’s research while affiliated with Brandeis University and other places

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Publications (274)


Historical Change in Midlife Trajectories of Self–Rated Health, Health Conditions, and Grip Strength: Comparison of the United States with Mexico, Europe, South Korea, and China
  • Preprint

May 2025

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14 Reads

Yesenia Cruz-Carrillo

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Empirical evidence has documented that later-born cohorts of middle-aged adults in the U.S. are reporting poorer mental and physical health than earlier-born cohorts. However, less is known about whether this is specific to the U.S. or generalizes to other nations and to what extent this is found for both self-report and objective indicators of physical health and how this might differ between men and women. Our study aims to examine similarities and differences in historical change of midlife development in self-rated health, health conditions, and grip strength by using harmonized data comprising longitudinal panel surveys from the U.S., Mexico, 13 nations in Europe, South Korea, and China. Results from multilevel models, stratified by gender, revealed historical stability in self-rated health and health conditions for middle-aged men in the U.S., whereas middle-aged women demonstrated historical declines in self-rated health and historical increases in health conditions. Historical improvements in self-rated health were observed for both men and women in England, Mediterranean Europe, Nordic Europe, and China. Historical decreases in health conditions were observed for both men and women in England and Mexico. Both men and women in the U.S. and China exhibited historical declines in grip strength, whereas both men and women in Nordic Europe and South Korea showed historical improvements. Our discussion focuses on better understanding these national gender differences in historical trends by considering how the dynamically changing historical context impacts ways of living and health care systems and the implications for developmental outcomes at the individual and population level.


Mapping Demographic Variations in Sense of Mastery Across the World: A Cross-National Analysis of 22 Countries in the Global Flourishing Study

April 2025

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10 Reads

Are certain parts of the world home to people with a higher sense of mastery? Does mastery vary across key demographic factors in similar or different ways across national contexts? These questions have been underexplored, or not explored at all. We analyzed nationally representative data from 22 countries in the Global Flourishing Study (N=202,898) and evaluated these questions. People with the highest mastery were found in countries from Latin America (e.g., #1 Mexico, #3 Argentina), the Middle East/North Africa (e.g., #2 Egypt), and in high-income societies across different regions (e.g., #4 Israel, #5 United States, #6 Spain, #7 Sweden, #8 Hong Kong, and #9 Australia). The results indicate that high a sense of mastery is achievable in diverse geographical and cultural contexts. Meta-analytic results that pooled country-specific estimates showed a progressive increase in mastery with age. Higher mastery was reported by people who were self-employed or employed by an employer, married, highly educated, regular attendees of religious services, and men. We also observed substantial heterogeneity in these factors across countries. Our research contributes to a more nuanced understanding of global patterns of mastery, and also suggests pathways for fostering mastery within and across diverse national contexts.


Early Echoes of Empowerment: Characterizing the Childhood Roots of Adult Sense of Mastery in a Cross-National Analysis of 22 Countries (in the Global Flourishing Study)

April 2025

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3 Reads

How might we cultivate a life imbued with a sense of mastery? An expanding body of research demonstrates that a heightened sense of mastery improves health and well-being outcomes. Despite this, it remains unclear which childhood factors foster increased mastery in adulthood. Further, existing studies have examined this question only within single countries. We analyzed nationally representative data from 22 countries in the Global Flourishing Study (N=202,898) and evaluated if 11 aspects of a child's upbringing predict mastery in adulthood, and also whether these associations vary by country. Some childhood factors were associated with increased mastery in adulthood, including good health, good relationships with mothers and fathers, economic stability, and regular religious service attendance. Childhood factors associated with decreased mastery in adulthood included abuse, feeling like an outsider in one’s family, poor health, economic hardship, and being female. However, there was little evidence that parent marital status or immigration status in childhood were associated with mastery in adulthood. Our meta-analysis also revealed substantial heterogeneity in childhood pathways to adult mastery across 22 countries. With further research, these findings could inform the development of globally adaptable, yet locally nuanced, programs and policies designed to foster a mastery across the globe.


Mapping Demographic Variations in Sense of Mastery Across the World: A Cross-National Analysis of 22 Countries in the Global Flourishing Study

April 2025

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2 Reads

Are certain parts of the world home to people with a higher sense of mastery? Does mastery vary across key demographic factors in similar or different ways across national contexts? These questions have been underexplored, or not explored at all. We analyzed nationally representative data from 22 countries in the Global Flourishing Study (N=202,898) and evaluated these questions. People with the highest mastery were found in countries from Latin America (e.g., #1 Mexico, #3 Argentina), the Middle East/North Africa (e.g., #2 Egypt), and in high-income societies across different regions (e.g., #4 Israel, #5 United States, #6 Spain, #7 Sweden, #8 Hong Kong, and #9 Australia). The results indicate that high a sense of mastery is achievable in diverse geographical and cultural contexts. Meta-analytic results that pooled country-specific estimates showed a progressive increase in mastery with age. Higher mastery was reported by people who were self-employed or employed by an employer, married, highly educated, regular attendees of religious services, and men. We also observed substantial heterogeneity in these factors across countries. Our research contributes to a more nuanced understanding of global patterns of mastery, and also suggests pathways for fostering mastery within and across diverse national contexts.


Mapping Demographic Variations in Sense of Mastery Across the World: A Cross-National Analysis of 22 Countries in the Global Flourishing Study

March 2025

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7 Reads

Are certain parts of the world home to people with a higher sense of mastery? Does mastery vary across key demographic factors in similar or different ways across national contexts? These questions have been underexplored, or not explored at all. We analyzed nationally representative data from 22 countries in the Global Flourishing Study (N=202,898) and evaluated these questions. People with the highest mastery were found in countries from Latin America (e.g., #1 Mexico, #3 Argentina), the Middle East/North Africa (e.g., #2 Egypt), and in high-income societies across different regions (e.g., #4 Israel, #5 United States, #6 Spain, #7 Sweden, #8 Hong Kong, and #9 Australia). The results indicate that high a sense of mastery is achievable in diverse geographical and cultural contexts. Meta-analytic results that pooled country-specific estimates showed a progressive increase in mastery with age. Higher mastery was reported by people who were self-employed or employed by an employer, married, highly educated, regular attendees of religious services, and men. We also observed substantial heterogeneity in these factors across countries. Our research contributes to a more nuanced understanding of global patterns of mastery, and also suggests pathways for fostering mastery within and across diverse national contexts.


Early Echoes of Empowerment: Characterizing the Childhood Roots of Adult Sense of Mastery in a Cross-National Analysis of 22 Countries (in the Global Flourishing Study)

March 2025

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14 Reads

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3 Citations

How might we cultivate a life imbued with a sense of mastery? An expanding body of research demonstrates that a heightened sense of mastery improves health and well-being outcomes. Despite this, it remains unclear which childhood factors foster increased mastery in adulthood. Further, existing studies have examined this question only within single countries. We analyzed nationally representative data from 22 countries in the Global Flourishing Study (N=202,898) and evaluated if 11 aspects of a child's upbringing predict mastery in adulthood, and also whether these associations vary by country. Some childhood factors were associated with increased mastery in adulthood, including good health, good relationships with mothers and fathers, economic stability, and regular religious service attendance. Childhood factors associated with decreased mastery in adulthood included abuse, feeling like an outsider in one’s family, poor health, economic hardship, and being female. However, there was little evidence that parent marital status or immigration status in childhood were associated with mastery in adulthood. Our meta-analysis also revealed substantial heterogeneity in childhood pathways to adult mastery across 22 countries. With further research, these findings could inform the development of globally adaptable, yet locally nuanced, programs and policies designed to foster a mastery across the globe.


Mastering the canvas of life: Identifying the antecedents of sense of control using a lagged exposure-wide approach

February 2025

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34 Reads

Applied Psychology Health and Well-Being

Accumulating studies have documented strong associations between a higher sense of control and improved health and well‐being outcomes. However, less is known about the determinants of increased sense of control. Our analysis used data from 13,771 older adults in the Health and Retirement Study (HRS)—a diverse, longitudinal, and national study of adults aged >50 in the United States. Using generalized linear regression models, with a lagged exposure‐wide approach, we evaluated how changes in 59 predictors (i.e., physical health, health behavior, and psychosocial factors) over a 4‐year period (between t0;2006/2008 and t1;2010/2012) might lead to changes in sense of control another 4‐years later (t2;2014/2016). After adjusting for a rich set of baseline covariates, changes in some health behaviors (e.g., sleep problems), physical health conditions (e.g., physical functioning limitations, eyesight), and psychosocial factors (e.g., positive affect, purpose in life) were associated with changes in sense of control four years later. However, there was little evidence that other factors were associated with a subsequent sense of control. A key challenge in advancing intervention development is the identification of antecedents that predict a sense of control. Our results identified several novel targets for interventions and policies aimed at increasing a sense of control.


TRAJECTORIES OF EPISODIC MEMORY IN MIDLIFE: HISTORICAL CHANGE FROM A CROSS-COUNTRY PERSPECTIVE

December 2024

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11 Reads

Innovation in Aging

According to the Flynn effect, cognitive abilities have improved across the past decades. However, we know little about whether such historical improvements generalize to middle-aged adults and differ across nations. In this study, we used harmonized data on episodic memory from nationally representative longitudinal panel surveys including the U.S., Europe, Mexico, and China to compare historical change in age-related trajectories of episodic memory among middle-aged adults. Our sample included 89,775 participants aged 45 to 65 years who provided 272,876 observations over up to 20 years. Longitudinal multilevel regression models revealed that today’s middle-aged adults in the U.S. perform worse on episodic memory tests than their age peers in the past. In contrast, today’s middle-aged adults in most other countries perform better than did their peers in the past. At the same time, later-born cohorts of U.S. middle-aged adults exhibited a more favorable episodic memory trajectory than earlier-born cohorts, whereas this trend was not observed in most other countries. Cohort trends remained significant when controlling for socio-demographic indicators (gender, education) and health measures (grip strength, number of chronic diseases). Women and individuals with higher levels of education, higher grip strength and fewer chronic diseases exhibited better episodic memory performance, and the association of grip strength with episodic memory was stronger in later-born cohorts. Our findings suggest that countries differ in the extent and direction of historical change in episodic memory scores and trajectories. More research is needed to better understand why the Flynn effect in the U.S. seems to be reversed.


WHEN AND HOW PERCEIVED CONTROL BUFFERS AGAINST COGNITIVE DECLINES: A MODERATED MEDIATION ANALYSIS

December 2024

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6 Reads

Innovation in Aging

People vary widely in their rates of age-related cognitive decline. Slower rates of decline have been linked to individual differences in perceived control, but less is known about how (mechanisms) and at what stage in the lifespan (moderators) this modifiable psychological resource is linked to preserved cognitive functioning. Our study examined changes in light physical activity (LPA) as an unexplored mechanism that may link changes in two facets of perceived control (personal mastery, perceived constraints) to 9-year trajectories of cognitive aging. We also examined whether mediated pathways were moderated by age (i.e., differed across the adult lifespan). We analyzed 9-year data from the Midlife in the United States Study (n=2,456; age= 56±11 years) using autoregressive mediation and moderated-mediation models. Mediation models showed that changes in personal mastery and perceived constraints predicted changes in LPA (βs=.06-.08, ps<.01), which in turn predicted 9-year changes in episodic memory and executive functioning (βs=.05-.13, ps<.02). Moderated-mediation models showed that, for episodic memory, the mediated pathways were strongest in old age and emerged only for constraints: For only older adults, declines in constraints predicted less decline in LPA (β=.11, p<.001), which in turn predicted slower declines in episodic memory (β=.05, p=.001). Results were consistent in sensitivity analyses that controlled for levels and changes in moderate-to-vigorous physical activity. Our findings inform lifespan theories of control and provide initial evidence that changes in a largely overlooked health behavior (LPA) may underlie the influence of perceived constraints on cognitive functioning, with this pathway becoming more pronounced in late life.


PSYCHOSOCIAL PROTECTIVE FACTORS FOR COGNITIVE AGING: THE MORE THE BETTER

December 2024

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9 Reads

Innovation in Aging

Research demonstrates that demographic (e.g., age, education) and behavioral variables (e.g., physical activity, smoking) are related to individual differences in cognitive aging. Although some work has examined modifiable psychosocial factors (e.g., control beliefs, purpose in life, social contact) in relation to cognitive aging, they are typically examined separately. To examine their additive rather than net effects, we standardized and averaged three psychosocial factors to create a continuous composite of sense of control, purpose in life, and social support in a sample of adults (N = 2,497, ages 28-85) from the second (2004-2006) and third (2013-2014) waves of the Midlife in the United States study. Using multiple regression, we tested the composite as a predictor of 9 to 10 year changes in episodic memory and executive functioning. Results showed that those higher on the psychosocial composite demonstrated less decline in both cognitive measures, even after controlling for established demographic, health, and behavioral risk factors of cognitive aging. We then assigned participants a score of 0 if they were below the median or a 1 if equal to or above the median on each psychosocial factor, such that total scores varied from 0 to 3. Those high on all three factors were better able to maintain their cognitive health compared to those who had fewer. These findings suggest that interventions that focus on a combination of psychosocial factors could be protective in reducing the rate of cognitive decline in middle and older adulthood.


Citations (53)


... In contrast to life satisfaction/evaluation, the outcomes of balance, inner peace and optimism are all increasing with age 44,45 . Patterns with mastery are similar but somewhat smaller in magnitude 46 . In contrast to many outcomes, suffering is not strongly patterned with age overall, or with religious service attendance, but there is notable variation in this across countries; suffering varies more 10, completely satisfied); Q2 (0, extremely unhappy; 10, extremely happy); Q3 and Q4 (0, poor; 10, excellent); Q5 (0, not at all worthwhile; 10, completely worthwhile); Q6, Q9 and Q10 (0, strongly disagree; 10, strongly agree); Q7 and Q8 (0, not true of me; 10, completely true of me); Q11 and Q12 (0, worry all of the time; 10, do not ever worry). ...

Reference:

The Global Flourishing Study: Study Profile and Initial Results on Flourishing
Early Echoes of Empowerment: Characterizing the Childhood Roots of Adult Sense of Mastery in a Cross-National Analysis of 22 Countries (in the Global Flourishing Study)
  • Citing Preprint
  • March 2025

... Individuals with a strong sense of purpose demonstrate more adaptive stress responses, including lower cortisol levels and faster recovery from stress [30,63]. These regulatory effects reduce systemic inflammation [64,65] and oxidative stress [66], both of which are closely linked to chronic diseases and aging-related health deterioration [67]. ...

The psychosocial anti-inflammatories: Sense of control, purpose in life, and social support in relation to inflammation, functional health and chronic conditions in adulthood
  • Citing Article
  • October 2024

Journal of Psychosomatic Research

... For example, the motivational theory of lifespan development (Heckhausen et al., 2010;Schulz & Heckhausen, 1996) connotes use of primary control strategies (efforts to control the environment, e.g. I don't give up until I solve the problem) increase through midlife, stabilize, then decrease in older adulthood, which has been mirrored in longitudinal studies of general control beliefs (Cerino et al., 2023;Lachman et al., 2009). Secondary control strategies (changing oneself to align with environmental forces, e.g. ...

Perceived Control Across the Adult Lifespan: Longitudinal Changes in Global Control and Daily Stressor Control (in press, preprint)
  • Citing Preprint
  • File available
  • October 2023

... Specifically, individuals who struggle to close this discrepancy gap, or to maintain current relationships, have an increased likelihood of experiencing loneliness (Baumeister and Leary 1995). Increasing empirical findings point to perceived loneliness as a public health concern in both in Europe and the United States (Infurna et al. 2024). Importantly, perceived loneliness has been associated with negative mental health implications, with a review identifying a wide range of negative emotional and cognitive outcomes including increased depressive symptoms, diminished executive control, and cognitive decline (Hawkley and Cacioppo 2010). ...

Loneliness in Midlife: Historical Increases and Elevated Levels in the United States Compared With Europe

... Besides, the study also explored the effects of the frequency, duration, and volume of PA at different intensities on successful aging, the results showed that VPA, MPA and LPA were all relevant in improving their aging outcomes. Two longitudinal studies from the United States and China [31,32] investigating PA and cognitive dysfunction have also shown that VPA, MPA, and LPA all have a positive effect on delaying cognitive dysfunction in older adults. Another study [33] about PA and cardiovascular disease risk in 660 older adults found that daily physical activity of any intensity and avoidance of sedentary behaviour were associated with a reduced risk of cardiovascular disease. ...

Increased frequency of light physical activity during midlife and old age buffers against cognitive declines

Journal of Behavioral Medicine

... Notably, the aperiodic exponent-equivalent to the negative linear slope of spectral power decay in log-log space-has been reported to decrease (i.e., become flatter) in older age (McKeown et al., 2025;Merkin et al., 2023;Tran et al., 2020;Waschke et al., 2017), possibly reflecting a shift toward noisier neural population spiking activity that degrades neural communication and disrupts cognitive performance (Tran et al., 2020;. Indeed, aperiodic activity is related to individual differences in cognitive performance in older adults (Finley et al., 2024;McKeown et al., 2025;Smith et al., 2023;Thuwal et al., 2021), with flatter spectral slopes mediating age-related declines in WM performance . ...

Resting EEG Periodic and Aperiodic Components Predict Cognitive Decline Over 10 Years

The Journal of Neuroscience : The Official Journal of the Society for Neuroscience

... In particular, basic traits such as the Big Five have turned out to be less stable than originally expected, and are variously susceptible to change, thereby showing a general tendency to develop in a positive direction until a decline takes the upper hand at an age that is much more advanced than in the past (Bleidorn et al. 2013;Damian et al. 2019;Roberts and Yoon 2022). A similar tendency suggesting a kind of growth in maturation and adjustment has been found for self-esteem, optimism and life satisfaction (Baird et al. 2010;Orth et al. 2018;Tetzner et al. 2024). ...

Stability and Change of Optimism and Pessimism in Late Midlife and Old Age Across Three Independent Studies

... Critical to the current study, consistent evidence shows that perceived control may moderate associations insofar that stress holds a less deleterious effect on individuals when they perceive greater control over their lives (Cerino et al., 2024) or the stressor itself (Bhanji et al., 2016). However, only recently have researchers turned to considering perceived control in daily life. ...

Perceived Control Across the Adult Lifespan: Longitudinal Changes in Global Control and Daily Stressor Control

... For example, a recent study of brain maturation found that controlling for the aperiodic components reversed the previous finding of decreasing alpha power from childhood to adolescence (Tröndle et al., 2022), whilst slowing of the EEG signal induced by electroconvulsive therapy has been shown to be better explained by an increase of the aperiodic exponent of the signal than by changes in oscillatory power (Smith et al., 2022). Moreover, aperiodic features themselves have been functionally linked to both aging (Cesnaite et al., 2022;Finley et al., 2023;Merkin et al., 2021;Voytek et al., 2015) and psychopathology (Karalunas et al., 2022;Peterson et al., 2021;Robertson et al., 2019), demonstrating their functional significance and the importance of incorporating them into the analysis of AD biomarkers. ...

Resting EEG Periodic and Aperiodic Components Predict Cognitive Decline Over 10 Years

... As neither PWH nor controls had significant improvements in ESE with structured exercise, establishing whether ESE captured during the intervention is reflective of continuation of exercise independently is warranted. Future interventions should incorporate additional strategies to improve ESE and sustain exercise habits, such as ongoing text messaging, coaching, or pharmacological support [37]. ...

Exercise and Behavior: Adjuncts to Pro-Myogenic Compounds for Enhancing Mobility in Older Adults
  • Citing Article
  • June 2023

The Journals of Gerontology Series A Biological Sciences and Medical Sciences