Margaret Rees’s research while affiliated with Oxford University Hospitals NHS Trust and other places

... Sexual problems are considered to be taboo subjects. Sexual health and wellbeing are extensively analyzed in the clinical guide entitled: "Sexual health and wellbeing and the menopause: an EMAS clinical guide" published in the current issue of Maturitas [1]. ...

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Menopause and sexual health: The elephant in the room

... This case study complies with the CARE guidelines for Clinical Case Reporting (Gagnier et al., 2013;Riley et al., 2017), and incorporates a qualitative analysis. Case reports serve as concise communications that share clinical experiences, and the lessons learned from their management (Ngene & Rees, 2024). In this case study, we aim to highlight the needs of a family undergoing a developmental transition and the role of the CNF throughout this process. ...

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Ontology-driven nursing practice: a case study in family nursing. Millenium -Journal of Education, Technologies, and Health

... The main characteristics of GD include its higher prevalence in women [8] and the difficulty of distinguishing it from other diseases, even when symptoms are present [9]. For example, menopausal symptoms such as tachycardia and sweating are difficult to distinguish from GD [10]. Consequently, the delayed diagnosis of GD has become a significant health concern, leading to a decline in quality of life [11][12][13]. ...

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Application of Thyroid Hormones in Women’s Hair for the Non-Invasive Prediction of Graves’ Disease

... Authors Kanakis et al. (2023) [14] updated the 2015 EMAS statement on TRT in older men with new research on late-onset hypogonadism and TRT through an expert consensus and literature review. Thus, TRT should only be offered to symptomatic older men with confirmed low testosterone concentrations after accounting for uncertainties regarding the long-term safety of this treatment. ...

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Major clinical studies on the relationship between testosterone levels and aging in men: a systematic review

... This is crucial as concerns may arise about unfeasibly long or short author lists [7]. In addition, there may be uncertainty about whether the authors and their institutions had the expertise to provide the reported clinical care [8]. Author order in the contributor statement has to be the same as that of the submission title page. ...

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Writing case reports: Sharing clinical experience to inform practice

... Vitamin D levels, as well as VDR expression, decrease with age, which is of particular importance for postmenopausal women, who, due to the cessation of estrogen synthesis and the consequent lack of its protective effect, are at greater risk of reduced bone mass, cardiovascular disease, metabolic disorders, unfavorable lipid profiles, diabetes, and atherosclerosis with all of its long-term consequences [22][23][24]. In addition, serum antioxidant activity decreases during the aging process, thus increasing the risk of oxidative stress, which, in turn, is involved in the initiation of the inflammatory process [25,26]. ...

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Differences in Chronic Low-Grade Inflammation and Metabolic Disturbances between VDR Genotypes in an Ethnically Homogenous Postmenopausal Female Population from Poland

... La deficiencia de vitamina D se ha asociado con una baja masa ósea, un aumento del riesgo de fracturas, enfermedades cardiovasculares, cáncer y ciertos trastornos infecciosos, como las infecciones respiratorias agudas y el COVID-19. Aunque la suplementación puede mejorar algunos aspectos de la salud, como el perfil lipídico y la glucosa en sangre, esta no tiene un impacto significativo en la incidencia de eventos cardiovasculares o cáncer y su efecto en los síntomas menopáusicos es limitado (33). Volumen embargo, presentan desventajas como la falta de especificidad de los anticuerpos utilizados y la interferencia significativa, lo que limita su capacidad para cuantificar formas individuales de vitamina D. La reactividad cruzada entre metabolitos similares puede introducir errores y disminuir la especificidad del método, y la calidad del anticuerpo utilizado es crucial para la calidad del ensayo. ...

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Consenso colombiano de vitamina D: recomendaciones de un panel de expertos de la Asociación Colombiana de Endocrinología, Diabetes y Metabolismo (ACE), 2025

... A quarter of menopausal women are so severely affected by their symptoms that they consider resigning from work, and according to the Women and Equalities Committee (Women and Equalities Committee, 2022) in just one year (2019), a million workdays were lost due to menopausal symptoms. Importantly, well-being and health during and after menopause are moderated by several psychosocial factors, including socioeconomic status, prior life experience (particularly early life adversity), ethnicity and culture, employment factors, and premenopausal health (Riach and Rees, 2022;Shanmugan et al., 2017). This points to the importance of considering diversity in menopausal experiences and the need to examine the effects of menopause in specific groups of individuals for whom menopause may unveil particularly difficult symptoms. ...

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Treatment of menopausal vasomotor symptoms and sensory issues in a 53-year-old autistic woman – a case report

... During the last two decades, after a reappraisal of the evidence emerging from the Women's Health Initiative (WHI) trial and by pooling data from other well-designed studies and meta-analyses, menopausal hormone therapy (MHT) has regained its position in the therapeutic armamentarium [1,2]. All scientific societies converge on the notion that MHT is the most effective treatment for the relief of bothersome vasomotor symptomatology (VMS) in postmenopausal women [1][2][3][4]. It may also reduce the risk of cardiovascular disease (CVD), if initiated promptly [i.e. in women <60 years of age or within 10 years since their final menstrual period (FMP)], providing a 'window of opportunity' [1][2][3][4]. ...

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Can menopausal hormone therapy be considered in postmenopausal women who are older than 60 years?

... During this period, women may encounter irregular menstrual cycles, hot flashes, mood changes, sleep disturbances, or metabolic imbalances. [2] Menopause itself marks the conclusion of the reproductive phase in a woman's life, signified by the permanent cessation of menstruation due to the loss of ovarian follicular function. This physiological event is diagnosed retrospectively after a continuous absence of menstruation for 12 consecutive months, with the average age of occurrence being 51 years. ...

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Unmasking the Hidden Links: Menopause, Andropause, and the Metabolic Puzzle. A Narrative Review