Manisha Das's research works

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Circulating tumor cells (CTCs) detection and isolation in different subtypes of early-stage breast cancer patients from Bangladesh.

Article

Jun 2023

e12529 Background: Breast cancer is a highly heterogeneous pathophysiology characterized by poor outcomes. Due to the increasing incidence and disease progression rates and undefined relapse periods, reliable disease monitoring is a challenge and has remained an unmet need. Advancements in liquid biopsy have significantly enhanced our understanding...

Reduced IFN-γ along with Changes in Hematological and Immunological parameters are Key to COVID-19 Severity in Bangladeshi Patients

Article

Full-text available

Nov 2022

The manifestation of COVID-19 severity and mortality has been associated with dysregulation of the immune response, often influenced by racial disparities and conferred by changes in hematological and immunological parameters. The biological and hematological parameters as well as the cytokine profiles have been investigated in a cohort of 61 COVID...

Figure 1: Representative electrophoretic patterns of TNF-a gene À308G>A...

Anthropological and biochemical parameters.

Clinical parameter analysis in regard to L308G>A genotype.

Tumour necrosis factor-α −308G/A polymorphism is associated with insulin secretory defects in Bangladeshi prediabetic/diabetic subjects

Article

Full-text available

Nov 2021

Objectives Tumour necrosis factor (TNF)-α, an adipocytokine, is closely linked to impaired glucose tolerance (IGT) and insulin resistance (IR) in type 2 diabetes (T2D) subjects. The relationship between the polymorphisms in the TNF-α gene and IR in Bangladeshi prediabetes and T2D subjects has not yet been fully identified. This study aims to reveal...