Mahalaqua Nazli Khatib’s research while affiliated with Datta Meghe Institute of Medical Sciences and other places

... From a public health perspective, the PNS 2019 results revealed the urgent need for a fundamental paradigm shift in public health policies, health care systems, research funding priorities, and resource allocation, all of which should emphasize primary and secondary prevention through lifestyle medicine. 47 Despite achieving some goals of the previous Brazilian Ministry of Health's Strategic Action Plan for Coping with Chronic Diseases, such as reducing smoking, 48 and increasing LTPA levels, 49 it is evident that there are still multifaceted and broader health challenges that require comprehensive attention. For example, despite a general increase in physical activity among the Brazilian population over the years, only 3.7% of the elderly meet international recommendations for muscle-strengthening activities. ...

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The 6 Pillars of Lifestyle Medicine and Prevalence of Cardiovascular and Cardiometabolic Diseases in Brazil: A Cross-Sectional, Population-Based Study Involving 88,531 Adults

... Hypertension is a prevalent chronic disease worldwide, with a steadily increasing incidence [1]. Approximately 1.28 billion adults aged 30-79 worldwide are estimated to have hypertension, with more than two-thirds residing in low-and middle-income countries [2]. Nearly half of these individuals are unaware of their condition, and approximately 40% of the hypertension cases remain undiagnosed and untreated [2]. ...

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Sex Differences in the Effects of Cadmium and Uric Acid Levels on Hypertension Risk: A Dose–Response Relationship and Synergistic Effect Study

... However, traditional COPD research has mostly focused on older populations, particularly in high-income countries. Compared to existing GBD 2021 studies [16,[33][34][35], this research focuses on the burden of COPD among young populations across varying socioeconomic levels and introduces novel analyses of health inequality and Frontier Analysis to assess disparities and achievable improvements in disease burden.We find that the burden of disease in these areas is decreasing at a much slower rate than in middlehigh SDI regions, and in some areas, it remains significantly high. Moreover, the analysis of health inequality reveals both absolute and relative inequities across socio-economic development levels. ...

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Epidemiological trends and risk factors of chronic obstructive pulmonary disease in young individuals based on the 2021 global burden of disease data (1990–2021)

... These classifications emphasize variations in frequency, duration, and symptomatology of the attacks. The pathophysiology of migraine is characterized by the activation of the trigeminovascular system, which triggers neurogenic inflammation, cortical spreading depression, and changes in cerebral blood flow, contributing to the typical migraine symptoms [7,8]. Despite its well-understood clinical features and pathophysiological mechanisms, the precise triggers of migraine remain highly individualized, with pharmacological agents increasingly recognized as potential contributors to the onset or exacerbation of attacks. ...

Reference:

Association between proton pump inhibitor use and migraine: a systematic review and meta-analysis

... Similarly to the effects of cigarettes, smoking cannabis aggravates inflammation in the lung, expressed by the elevated number of neutrophils and macrophages, with their functional impairment [111,113,114]. Additionally, cannabis smoke, like tobacco smoke, is believed to worsen respiratory symptoms, such as cough, wheezing, and dyspnea [111,[115][116][117][118]. It increases the risk of airway obstruction and exacerbation of lung diseases; however, the evaluation is difficult to untangle due to the common concurrent use of tobacco [65,116,[119][120][121]. ...

Reference:

Is There a Place for Cannabinoids in Asthma Treatment?

... Risk factors for hypertensive disorders of pregnancy include family history of hypertension and diabetes, previous diagnosis of hypertension before pregnancy (the risk of occurrence of gestational hypertension and preeclampsia increased with the presence of elevated BP and stage 1 hypertension) [15], previous history of preeclampsia in pregnancy, being overweight, unhealthy eating and alcohol consumption [16], female history of polycystic ovarian syndrome [17], higher plasmic values of hormone TT3 [18], and higher sex hormone-binding globulin values (a potential biomarker for pregnancy complications) [19]. It was also found that specific ophthalmic Doppler parameters are associated with the risk of preeclampsia, as preeclamptic women exhibited differences in three out of six measured values compared to normotensive women. ...

Reference:

A Comprehensive Review of Current Advancements in the Diagnosis, Treatment, and Long-Term Implications of Hypertensive Disorders of Pregnancy

... Asthma signifcantly burdens global health, with the World Health Organization (WHO) reporting that 3%-5% of adults and 7%-10% of children are afected [1,4]. Te WHO predicts that the number of people with asthma will rise from 100 to 150 million to over 200 million by 2025, with 180,000 new cases annually [4,5]. Asthma is characterized by airway infammation, heightened sensitivity, and obstructed airfow, which challenges healthcare systems and signifcantly impacts patients' quality of life [6]. ...

Reference:

Proton Pump Inhibitor Use and Its Association With Asthma: A Systematic Review and Meta-Analysis

... Hospital robots operating with AI technology conducted disinfection duties, supply operations, and symptomatic patient checks that preserved human staff from contact during the COVID-19 pandemic. The UVD Robot is an autonomous machine that accomplishes hospital surface disinfection with AI control of ultraviolet light technology [9]. TUG from Aethon and other AI robots provide medical equipment transport and unstable terrain navigation in disaster zones to keep healthcare access active during dangerous circumstances. ...

Reference:

Artificial Intelligence Algorithms and Applications in Medical Robotics

... Viral infections, such as HIV [141], dengue viral infection [142], Japanese encephalitis [143], measles [144], and COVID-19 [145], have been linked to movement abnormalities like chorea [146], dystonia [147], myoclonus, cranial [148], and parkinsonism due to direct neurotropism and immune-mediated damage [149]. Bacterial infections, including syphilis [150,151], tuberculosis [152], Lyme disease [153], mucormycozis [154], Bartonella henselae [155], may lead to tremors [156], chorea, parkinsonism-plus syndromes [157], and ataxia when the nervous system is involved; also, Jarisch-Herxheimer reaction [158] is an acute inflammatory response that can occur after initiating antibiotic treatment for syphilis [159]. Post-infectious autoimmune syndromes, such as Sydenham's chorea following Group A streptococcal infection [160], result from molecular mimicry and basal ganglia dysfunction, causing hyperkinetic movements. ...

Reference:

Global Research Trends in Drug-Induced Movement Disorders: A Bibliometric Analysis

... In this context, there is a growing interest in identifying reliable, accessible, and cost-effective biomarkers to predict adverse clinical outcomes at an early stage, especially in mechanically ventilated patients. Among the numerous laboratory parameters routinely used in ICU settings, serum albumin and D-dimer have individually been shown to provide prognostic insights in various acute conditions, including sepsis, COVID-19, and trauma-related complications [1][2][3][4][5][6][7][8][9][10]. ...

Reference:

Association of Albumin-to-D-Dimer Ratio with Mortality in Mechanically Ventilated Intensive Care Patients