M. Seman's research while affiliated with Monash University (Australia) and other places
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Publications (28)
Purpose:
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a complex and high-risk life support modality used in severe cardiorespiratory failure. ECMO survival scores are used clinically for patient prognostication and outcomes risk adjustment. This study aims to create the first artificial intelligence (AI)-driven ECMO survival score...
Purpose: Venoarterial extracorporeal membrane oxygenation (ECMO) is a complex and high-risk life support modality used in severe cardiorespiratory failure. ECMO survival scores are used clinically for patient prognostication and outcomes risk adjustment. This study aims to create the first artificial intelligence (AI)-driven ECMO survival score bas...
Background
In patients with aortic stenosis (AS), the presence of mitral regurgitation (MR) can lead to underestimation of AS severity and worse clinical outcomes. The objective of this study was to characterize the magnitude of the effects of concomitant MR on hemodynamic indicators of AS severity using clinical data and a computational cardiovasc...
Interaction between native ventricular output and venoarterial extracorporeal membrane oxygenation (VA ECMO) flow may hinder oxygenated blood flow to the aortic arch branches, resulting in differential hypoxemia. Typically, the arterial cannula tip is placed in the iliac artery or abdominal aorta. However, the hemodynamics of a more proximal arteri...
Background
Defibrillation guidelines recommend avoiding patient contact during shock delivery. However, hands-on defibrillation (compressions during shock) and manual pressure augmentation (MPA – pushing on the defibrillator pads during shock) may lead to improved clinical outcomes. There are limited data addressing the protection provided by perso...
Interaction between native ventricular output and venoarterial extracorporeal membrane oxygenation (VA ECMO) flow may hinder oxygenated blood flow to the aortic arch branches, resulting in differential hypoxemia. Typically, the arterial cannula tip is placed in the iliac artery or abdominal aorta. However, the hemodynamics of a more proximal arteri...
Background: The interaction between native left ventricular output and venoarterial extracorporeal membrane oxygenation (VA ECMO) flow may hinder perfusion of oxygenated blood to the aortic arch branches, resulting in differential hypoxia. Typically, the arterial cannula tip is placed in the iliac artery or abdominal aorta. However, the hemodynamic...
A ‘cardio‐geriatric’ heart failure model of care was implemented to address the high rates of readmission in elderly acute decompensated heart failure patients. Despite demonstrably intensified management in both the cardiology and geriatric domains, this study did not demonstrate a positive effect on the primary outcome of all cause readmissions a...
Aims:
Health services worldwide face the challenge of providing care for increasingly culturally and linguistically diverse (CALD) populations. The aims of this study were to determine whether CALD patients hospitalised with acute heart failure (HF) are at increased risk of rehospitalisation and emergency department (ED) visitation after discharge...
Objective: To evaluate the effect of language barriers on time to thrombolysis and clinical outcomes in acute ischemic stroke.
Background: Acute stroke is a time-critical emergency where diagnosis and management are highly dependent upon accuracy of patient’s history. We hypothesised that limited English proficiency is associated with delayed onse...
Doctor–patient language discordance has been shown to lead to worse clinical outcomes. In this study of patients undergoing primary percutaneous coronary intervention for ST‐elevation myocardial infarction at an Australian health service, we demonstrated that limited English proficiency (LEP) is an independent predictor of prolonged symptom‐to‐door...
Background
Acute heart failure (AHF) is a frequent reason for hospitalization worldwide and effective treatment options are limited. It is known that AHF is a condition characterized by impaired vasorelaxation, together with reduced nitric oxide (NO) bioavailability, an endogenous vasodilatory compound. Supplementation of inorganic sodium nitrate (...
Citations
... BB, beta-blocker; bpm, beats per minute; CAD, coronary artery disease; CCB, calcium channel blocker; dilt, diltiazem; ED, emergency department; EF, ejection fraction; eGFR, estimated glomerular filtration rate; HBS, hospital-based specialist in internal medicine; HF, heart failure; IV, intravenous; KP, Kaiser Permanente; outpt, outpatient; Pharm, pharmacologic cardioversion; pt, patient; RVR, rapid ventricular response; w/, with electrical cardioversion [39,41,92,93]. Manual pressure augmentation has been shown to be safe for the proceduralist [39,94]. It can be helpful for all patients, but more so for obese patients, who fail electrical cardioversion at twice the rate of non-obese patients [39]. ...
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... Such specialists bring added value to usual care by combining geriatric and cardiologic expertise, both of which are essential for this specific population. 24 Interestingly, we identified a J-curve phenomenon characterizing the relationship between extreme SBP and increased mortality, which has already been shown in HFpEF. 25 An SBP target of 130-139 mmHg, as recommended by the European Society of Cardiology (ESC), 26 appeared to be associated with a better prognosis. ...
... 89 Another study demonstrated that culturally and linguistically diverse populations in Australia with limited English language proficiency were at an increased risk for rehospitalization and emergency department visits, with a greater cumulative incidence of HF-related readmissions and emergency department visitations. 92 Habits, good and bad, are built over the life course through socialization. These habits commonly include substance use such as alcohol and tobacco, dietary habits, and exercise. ...
... Limited English proficiency (LEP) is increasingly recognized as an independent barrier to timely healthcare access and optimal outcomes (1)(2)(3). In the context of the dynamic COVID-19 pandemic, healthcare communication with the public is vital for timely access to testing, treatment, and vaccination. ...
... This disease has tremendous undesirable consequences which can lower the quality of life and even lead to death [25]. Numerous human intervention studies have investigated the effects of dietary nitrate on vascular health [3,13,26,27]. These studies have shown that increased nitrate intake can improve vasorelaxation [27], lower blood pressure [2] and improve function of endothelium [4], which eventually resulted in lower death risk of atherosclerotic vascular disease (ASVD) [10]. ...
