October 1971
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8 Reads
Planta Medica
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Publications (7)
May 1971
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290 Reads
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88 Citations
Planta Medica
The non–phenolic fraction obtained from the gurn resin of Boswellia serrata Roxb. was found to exhibit marked sedative and analgesic effects. The drug produced a reduction in the spontaneous motor activity and caused ptosis in rats. A significant analgesic effect was observed as evaluated by both the hot–wire and the mechanical pressure methods. These effect started within 30 minutes and lasted for about 2 hours. Nalorphine caused only an insignificant antagonism to the analgesic effect of the drug. The fraction potentiated the secobarbitone–induced hypnosis in rats. The secondary–conditioned response (SCR) was specifically blocked in the trained rats, whereas the conditioned–avoidance response (CAR) was not significantly affected.
August 1970
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14 Reads
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4 Citations
Indian Journal of Physiology and Pharmacology
June 1970
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11 Reads
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3 Citations
Planta Medica
Das aetherische Öl von Colubrina asiatica wurde pharmakologisch untersucht. Es zeigte keinen deutlichen Einfluß auf die Aktivität des zentralen Nervensystems, erniedrigte aber deutlich die rektale Temperatur ohne Sedierung. An anaesthesierten Hunden wurde ein deutlicher hypotensiver Effekt und am Froschherzen eine schwächende Wirkung beobachtet. Beide „Wirkungen konnten durch Atropin blockiert werden. Das Öl wirkte antagonistisch auf den spasmatischen Effekt von Acetylcholin, Histamin und Barium auf die weiche Muskulatur, während es an der Skelettmuskulatur teilweise die kontrahierende Wirkung von Acetylcholin aufhob.
May 1970
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62 Reads
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11 Citations
Indian Journal of Experimental Biology
February 1970
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39 Reads
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13 Citations
Indian Journal of Experimental Biology
November 1969
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58 Reads
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20 Citations
Life Sciences
Studies on the pharmacology of the gum resin of Boswellia serrata Roxb. showed that its sedative and analgesic effects reside in the non-phenolic fraction. This fraction produced analgesic effect in albino rats as seen by both the hot-wire and mechanical compression methods. Both the sedative and analgesic effects of the fraction were antagonized by treatment of the animals with sub-analgesic dose of morphine hydrochloride.
Citations (6)
... A distilled mixture of whole fruits of C. asiatica L. is reportedly used as an abortifacient as well as a piscicide and migraine remedy [4]. The essential oil of the fruit has a blood pressure reducing effect and induces spasmolytic activity [5]. A significant cancer inhibiting compounds have been identified and isolated in six New World species of the Genus Colubrina [6]. ...
- Citing Article
June 1970
Planta Medica
... Hotwire and mechanical compression methods were employed in the rat models to induce pain. The results revealed that non-phenolic fraction of the plant exhibited analgesic effect 85 . ...
- Citing Article
November 1969
Life Sciences
... It is also reported for relieving pain, arousing sexual power, aches, sore eyes, skin infections, gouty joints, wounds and also for producing a soothing effect on the body [1][2][3]. The leaf extract has been evaluated for cardiovascular and antiinflammatory activities [4]. The berries oil is used in the treatment of rheumatism and shampoo preparation [5]. ...
- Citing Article
February 1970
Indian Journal of Experimental Biology
... The essential oil of M. tomentosa exhibited pain-relieving property. 4 Bioactive alkaloids such as 10methoxyliriodenine and 10-hydroxyliriodenine isolated from M. cf. banacea showed toxicity against DNA repair. ...
- Citing Article
May 1970
Indian Journal of Experimental Biology
... The plant grows in Bangladesh, India, Sri Lanka, Myanmar, China, and Malaysia as described by Uddin [6]. Mandal et al. [19] reported antimicrobial, Kar et al. [20] cardiovascular, and Menon et al. [21] psychopharmacological activity. Agrawal et al. [22] isolated four butenolides, Wang et al. [23] 2 -oxygenated flavone glycoside, and Herath et al. [24] D-xylose and L-arabinose from the plant. ...
- Citing Article
August 1970
Indian Journal of Physiology and Pharmacology
... It is 30ft long tree native to Deccan peninsula of India and also found in some parts of Africa. 40 Zeeyauddin and 60% respectively. Study reinforced traditional claim of Boswellia serrata for its antiulcer efficacy 41 . ...
- Citing Article
May 1971
Planta Medica