Lisandra Mendoza's research while affiliated with United States Department of Veterans Affairs and other places
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Publications (11)
Objective
The aim of the current study was to examine associations between depression and clinical functioning among a multi-ethnic sample.
Methods
35 cognitively normal and Mild Cognitive Impairment (MCI) participants were included and self-identified as Hispanic or white non-Hispanic (WNH). The Hispanic group (n=18), had a mean age of 70.83 (SD=...
The Apolipoprotein E (APOE) gene is a major risk factor in developing late‐onset Alzheimer’s disease (AD; LOAD; de Oliveira et al., 2017; de Oliveira et al., 2014). The relationships between E4 genotype, brain morphology and ethnicity may provide insights into mechanisms by which ethnicity is associated with risk for AD. Because most research on ge...
Objectives: There are few standardized, Spanish-language diagnostic tools to help identify Hispanic persons at early stages of Alzheimer’s disease (AD). This study evaluated the accuracy of the Spanish version of the Repeatable Battery for the Assessment of Neuropsychological Status-Update (RBANS) in predicting AD in older Hispanic adults in the Un...
Objectives: This study examined the association of cultural factors and literacy to neuropsychological performance and measures of regional brain atrophy among Hispanic elders diagnosed with amnestic Mild Cognitive Impairment (aMCI).
Method: Acculturation and literacy levels were measured among 45 subjects tested in Spanish; their primary language....
The effect of acculturation on cognition was examined among 142 older Hispanics: cognitively normal [CN; n = 70], Mild Cognitive Impairment, amnestic [aMCI; n = 27], and Dementia [D; n = 45]. Acculturation levels (high vs. low) were determined using the Short Acculturation Scale for Hispanics (SASH). ANCOVAs used a wide variety of neuropsychologica...
The most promising biomarkers to date for Alzheimer’s disease (AD) detection include Positron Emission Tomography (PET) of metabolic brain changes or cortical b-amyloid deposition, structural Magnetic Resonance Imaging (MRI) for brain atrophy, and cerebrospinal fluid (CSF) biomarkers (Neeti, & Singh, 2016; Humpel, 2011; Frisoni, Fox, Jack, Jr. Sche...
Citations
... Fourth, we did not test the association of brain measures with cognitive outcomes although we did conduct a sensitivity analysis excluding those with mild cognitive impairment ( Dong et al., 2015 ;Fletcher et al., 2018 ). Fifth, we did not test for modification by social determinants of health (e.g., access to insurance, literacy; Rodriguez et al., 2022 ;Sadhu et al., 2019 ) which may point to potential modifiable factors related to brain aging. Further work will more completely address these issues. ...
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... This not only helps immigrants perform daily activities in their new world but also yields an important impact on health and well-being. Although the role of acculturation varies with the domains of health and by age groups [4][5][6][7], low acculturation has been consistently identified as a life stressor that threatens older immigrants' mental health [8][9][10]. ...
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