Lei Xue's research while affiliated with China Medical University (PRC) and other places

Publications (19)

Article
Full-text available
Objectives: The aim of this study was to describe our experience in treating chronic obstructive parotitis (COP) related to diabetes. Methods: Twelve patients with COP related to diabetes were selected for the study. A sialendoscope was introduced from the orifice to investigate the ductal wall and lumen. During the operation, chymotrypsin and gent...
Article
Objectives: Chronic obstructive parotitis related to Sjogren syndrome is not uncommon, but it is rarely reported in the literature. The aim of this study was to describe our experience in the treatment of chronic obstructive parotitis related to Sjogren syndrome. Study design: Seventeen cases of chronic obstructive parotitis related to Sjogren s...
Article
Osteopetrosis represents a heterogeneous group of rare, hereditary bone disorders with variable clinical features, and an increase in bone density. Osteomyelitis of the jaws is a significant complication of osteopetrosis. In this article, a reported patient with osteopetrosis complicated by osteomyelitis of the mandible was examined. The patient wa...
Article
Purpose: The aim of this study was to describe the effect of vancomycin-impregnated calcium sulfate in the treatment of osteomyelitis of the jaw. Materials and methods: Twelve patients who were diagnosed with osteomyelitis of the jaw underwent treatment with vancomycin-impregnated calcium sulfate since July 2014 at the Department of Oral and Max...
Article
Purpose: Periorbital infantile hemangiomas (IHs) require early intervention because they have the potential risk of causing visual disturbances. In recent years, propranolol has shown promise in the effective management of periocular and periorbital IHs. The objective of our study was to assess the clinical outcomes, efficacy, and safety of propra...
Article
Purpose: The combination treatment for mix infantile hemangiomas (IHs) using oral propranolol with topical timolol maleate was not well documented in the literature. The aim of this study was to evaluate the therapeutic effects and safety of oral propranolol along with topical timolol maleate or oral propranolol alone for treating mixed IHs in the...
Article
Full-text available
The aim of the present study was to examine the biocompatibility of transforming growth factor-β1-silk fibroin-chitosan (TGF-β1-SF-CS) scaffolds. In order to provide an ideal scaffold for use in bone tissue engineering, TGF-β1 was introduced into the SF‑CS scaffold in order to reconstruct a three dimensional scaffold, following which hFOB1.19 osteo...
Article
The objective of the study was to discuss the biocompatibility of VEGF-silk fibroin-chitosan (VEGFSF- CS) three-dimensional scaffolds in order to offer an ideal scaffold for bone tissue engineering. Bone marrow derived mesenchymal stem cells (BMSCs) were seeded on the VEGF-SF-CS three-dimensional scaffolds and silk fibroin-chitosan (SF-CS) three-di...
Article
Chronic obstructive parotitis (COP) is the most common non-neoplastic salivary disorder. The aim of this study was to describe the authors' experience using sialendoscopy for diagnosing and treating COP. Thirty-one patients with COP who were treated with sialendoscopy from January 2013 through June 2014 at the Department of Oral and Maxillofacial S...
Article
The aim of the present study was to evaluate the therapeutic outcome of using electrochemical therapy (ECT) combined with a sclerosing agent, pingyangmycin (bleomycin A5 hydrochloride; PYM), for large (>3 cm in diameter) venous malformations (VMs) in the oral and maxillofacial regions. Thirty-five patients (15 male and 20 female; age range, 10 to 6...
Article
The objective of this study was to assess the clinical effects and safety of topical timolol maleate for the management of superficial infantile hemangiomas (IHs). From October 2012 to March 2014, 35 infants (24 girls and 11 boys; 2 to 10 months old; median age, 4.7 months) with superficial hemangiomas were treated with the local application of tim...
Article
Purpose The aim of this study was to investigate the therapeutic results and effects of propranolol on cardiovascular parameters in infants with systemic propranolol for complicated infantile hemangiomas (IHs), as well as to evaluate the adverse effects of propranolol throughout the course of treatment. Materials and Methods Twenty-five consecutiv...
Article
Purpose: To evaluate the clinical effect of using different concentrations of pingyangmycin to treat venous malformations in oral and maxillofacial region. Methods: One hundred and ninety-four patients with venous malformations in oral and maxillofacial region were included and treated by pingyangmycin injection with different concentrations. Fo...
Article
Purpose: To investigate the therapeutic effects of pingyangmycin injection as a primary therapy of macrocystic lymphatic malformations in cervical region. Methods: Thirty-six patients with macrocystic lymphatic malformations in cervical region underwent the therapy of pingyangmycin injection between 2009 and 2012 at School of Stomatology, China...
Article
We investigated the clinical efficacy of propranolol in treating proliferating infantile haemangiomas, and the serological changes in vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthase (eNOS) during treatment. Propranolol was given orally to 35 infants with proliferating haemangiomas in a dose of 1.0-1.5mg/kg/day. Hemis...
Article
The objective of this study was to summarize our experience of using local flaps for the reconstruction of neck defects after cervical contractures release, particularly of using the extended deltopectoral flaps whose distal margin was beyond the anterior axillary line even reaching dorsalis for reconstruction of anterior neck scar contractures in...
Article
To investigate the clinical effect of electrochemical therapy (ECT) combined with pingyangmycin (PYM) injection for the treatment of high-return flow venous malformation. A total of 68 cases of the high-return flow venous malformation were retrospectively analyzed, in which 32 cases received simplely ECT,and 36 cases received ECT combined with PYM...
Article
To explore the therapeutic effect of electrochemical therapy(ECT) for high-flow vascular malformation in maxillofacial region. 38 patients with high-flow vascular malformation in maxillofacial region were treated with ECT. The voltage was 6-8 V, and the electric current was 80-100 mA. The electric quantity was 10-20 C/cm2. Among the 38 cases, 32 ca...
Article
We explored the effect of electrochemical therapy for the treatment of high-flow venous malformations in the maxillofacial region in 32 patients. We used a method of anaesthesia that was suitable to the site and size of the lesion, and then inserted platinum needles into the lesion in a sterile environment. We protected the normal skin by inserting...

Citations

... Chronic obstructive parotitis (COP) is a common clinical disease in which the affected parotid gland repeatedly becomes swollen and painful, especially when patients consume sour food or when they eat in general (Wu et al., 2015a;Guo et al., 2017). Diabetes is a metabolic disease that is characterized by hyperglycemia and can directly or indirectly harm the body. ...
... Classical osteopetrosis has distinct subforms, which are classified into three clinical groups according to age of onset, inheritance, and severity. 8 Autosomal recessive osteopetrosis (ARO), malignant form, is typically fatal during early infancy when not treated. The second form is an autosomal recessive intermediate form that manifests dur-ing childhood, with significant severe signs and symptoms compared to benign osteopetrosis. 3 There is also an autosomal dominant benign adult type that is associated with few symptoms, which is the most common subtype. ...
... On the other hand, the study cohort is rather small, thereby limiting the power of statistical analysis. However, most previous studies examining the usage of calcium-sulfate-based antibiotic carriers in chronic OM were comparably small [32][33][34][35][36][37][38]. Future studies need to address the cohort size in order to sufficiently provide recommendations on the usage of bone void fillers. ...
... In many cases, these lesions are not clearly visible on the skin. [17][18][19] In general, they do not change during crying or Valsalva maneuvers, as is the case with VMs. ...
... It was observed that the mean time duration to resolution was evidently shorter with prominent color fading in the experimental group over the control. [13] Deep hemangiomas in 5 subjects in a study were treated with topical timolol 0.5% solution alone as three drops three times a day. Complete regression was noticed after about 10 months. ...
... It was necessary to estimate the toxicity of the obtained SeB-NPs and Ag SeB-NPs for further tissue engineering applications. Osteoblasts were commonly used to evaluate the cytocompatibility of nanoparticles and/or scaffold in tissue engineering 58,59 . In this study, the cytocompatibility of SeB-NPs and Ag SeB-NPs was assessed by culturing with hFOB 1.19 cells. ...
... While evidence of symptom resolution following sialendoscopy in the treatment of nonstone disorders has been reported, prior studies have been largely retrospective and of smaller sample sizes. 14,19,[21][22][23] These retrospective analyses have demonstrated successful long-term complete or significant symptom resolution in 70% to 88% of patients following sialendoscopic procedures. 14,23 This prospective study echoes these findings to show that significant symptom reduction can be achieved in over half of patients with chronic idiopathic sialadenitis following treatment with sialendoscopy, although this patient population requires longitudinal follow-up due to high rates of symptom persistence and recurrence. ...
... [19][20][21][22][23][24][25] Several observational studies have reported the feasibility of applying electricity to increase the effect of sclerotherapy for VMs. [26][27][28][29] However, in contrast to our investigation, these previous studies described a different electrochemical treatment method combined with pingyangmycin, which is a variant of bleomycin. In these studies, a continuous low current was applied for a longer period (6-8 V at 80-100 mA for a mean period of 5.4 minutes) via a positive and negative electrode. ...
... Topical timolol, a nonselective beta blocker, is another good treatment option, especially for superficial IHs, considering its fewer systemic effects 14,15 . Timolol maleate is 8 times more potent than propranolol as a beta blocker, and its lipophilic nature can enhance transcutaneous penetration 16 . A randomized placebocontrolled trial in infants aged 5~24 weeks reported that treatment with topical timolol 0.5% gel for 24 weeks is a safe and effective therapy for patients with superficial IH 17 . ...