Laura Gianolio's research while affiliated with Ospedale dei Bambini Vittore Buzzi and other places

Publications (12)

Article
Full-text available
Background A severe multisystem inflammatory syndrome in children (MIS-C) related to SARS-CoV-2 has been described after infection. A limited number of reports have analyzed the long-term complications related to pro-inflammatory status in MIS-C. We evaluated multiorgan impairment at the 6-month follow-up in MIS-C. Methods We enrolled 33 pediatric...
Article
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Background: Inflammatory bowel disease (IBD) patients show a higher risk of developing metabolic and cardiovascular diseases due to the presence of systemic low-grade chronic inflammation. Exercise can improve cardiovascular fitness and modulate the inflammatory processes. We evaluated the physical activity (PA) level and the fitness performance o...
Article
Full-text available
Background: In the Lombardy Region, Italy, HPV vaccination is recommended and offered free of charge to 12-years-old males since 2017. The expected vaccination thresholds are still far to be reached. Methods: A cross-sectional survey to investigate parents’ attitudes towards the HPV vaccine and knowledge about HPV was administered to parents of boy...
Article
Full-text available
Multisystem inflammatory syndrome in children (MIS-C) is a severe hyperinflammatory disease related to SARS-CoV2 infection, with frequent cardiovascular involvement in the acute setting. The aim of the study was to evaluate the cardiac function at 6 months. Thirty-two patients diagnosed with MIS-C were enrolled and underwent advanced echocardiogram...
Article
Full-text available
Congenital cytomegalovirus infection (cCMV) is the most common congenital viral infection, with a consistent rate of morbidity, mortality, and long-term sequelae, especially in the case of late diagnosis. Nevertheless, a universal screening for CMV is not currently recommended, and global awareness about this infection, as well as accurate and shar...
Article
Full-text available
Emergency rooms (ER) are largely used by patients with oral complaints, who choose the ER over private or public dental offices for oral prevention and treatment. During the COVID-19 pandemic, the activity of most dental facilities was limited, and most hospitals and ERs were dedicated to the treatment of COVID-19 patients. The present study analyz...
Article
Full-text available
While the risk of SARS-CoV-2 infection and/or COVID-19 disease progression in the general population has been largely assessed, its impact on HIV-positive individuals remains unclear. We present clinical and immunological data collected in a cohort of HIV-infected young individuals during the first wave of COVID-19 pandemic. SARS-CoV-2 RNA, virus-s...
Conference Paper
Introduction While severe manifestations of congenital Cytomegalovirus (CMV) transmission are widely investigated, little is known about postnatal CMV (pCMV) infection. Although pCMV infection in term healthy infant is mostly asymptomatic, serious gastrointestinal symptoms (vomiting, diarrhea, abdominal distension, hepatosplenomegaly, blood stools)...
Conference Paper
Congenital cytomegalovirus infection (cCMV) is the most common congenital viral infection; however, a poor rate of awareness is reported worldwide. Congenital cytomegalovirus’ most frequent and severe expression is represented by neuro-audiological impairment. We report two cases of late diagnosed cCMV associated with severe neuro-radiological alte...
Article
Full-text available
Altered level of consciousness (ALC) represents a neurological emergency, which demands a methodical approach to evaluation and treatment. Emergency departments’ Paediatricians dealing with children with ALC need a rapid and reliable diagnostic process to rule out life-threatening conditions. ALC can be caused by structural and non-structural condi...
Article
Background: While other viral infections occurring in early pregnancy are known to be associated with fetal cardiac malformations, little is known about CMV and its causative role. Only a few case repots have been described reporting a correlation between congenital CMV infection and cardiac defects. Case-report: We report the case of a 7-day-old n...

Citations

... Although exercise provides multiple health benefits for children and adolescents with obesity, the main problem in this population is the promotion of an active lifestyle and adherence to exercise programs. In fact, children with obesity tend to have a lower perception of their ability to perform exercise [100,101] and this decreased self-confidence leads children and adolescents to avoid highly competitive activities or settings. For this reason, several studies have investigated new modalities to increase adherence to exercise, and some studies highlighted the efficacy of exergames and online supervised training in lowering the dropout rate and promoting a healthy lifestyle compared to regular training modalities in children with obesity [102,103]. ...
... There were 206 publications that resulted with our keyword search on MIS-C and follow-up between 2020 and 2022. Eleven published studies fit the inclusion criteria with a total of 343 participants (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). All studies included patients who met criteria for MIS-C per the CDC guidelines (see Figure 1). ...
... For example, a study performed in Italy on 85 PLWH found that they do not develop higher clinical severity or demonstrate increased risk for COVID-19. Moreover, HIV-1-and SARS-CoV-2-positive patients have higher levels of IL-10, thus suggesting an IL-10-mediated role in SARS-CoV-2 infection in PLWH [35]. Another important issue that has been poorly addressed is the prevalence of long-COVID-19 in PLWH taking cART. ...
... Nevertheless, the three cases of congenital cardiopathy are a peculiarity of our population. Only four isolated case reports of cardiomyopathy linked to cCMV infection were reported in the literature [27][28][29][30]. Although CMV is a relatively frequent cause of myocarditis in childhood, studies on the relationship between cCMV and cardiac involvement are lacking. ...