Larry I. Lipshultz's research while affiliated with Baylor College of Medicine and other places

... Goldstein et al collected and analyzed 5-year outcome information from patients previously enrolled in IMPRESS I and II, as well as two additional open-label studies. 49 They found an additional 9% decrease in curvature as well as a decreased PDQ bother score, five years after initial treatment. 8 Although subsequent study designs have varied, multiple studies have demonstrated an improvement in the degree of curvature ranging from 13° to 23°. ...

... The classic treatment for ejaculatory duct obstruction is transurethral resection of ejaculatory ducts (6,7). Although the therapeutic effect of this surgical method has been proven, it is more traumatic and more likely to have postoperative complications. ...

... 61 Theoretical advantages include elimination of physiological tremor, increased ergonomics, stable magnification, reduced learning curve and removal of the need for a skilled microsurgery assistant. 62 There is a clear, albeit rare, advantage in the setting of repair of intraperitoneal vasal obstruction. 63,64 Urology trainees, who have an early exposure to robotics because of its widespread use, may have an advantage over other surgical specialties with the application of robotic technologies to surgical procedures. ...

... 50 In the era of assisted reproductive technology (ART), remarkable energy is invested in improving embryo quality and pregnancy success, but the merit of proper male evaluation and pre-treatment strategies is overlooked as ICSI can provide the couple with a baby without the need to explain the nature of underlying male infertility. 44,[51][52][53] However, the notion that SDF could impair reproductive outcomes has prompted the use of SDF testing in clinical settings, 54 albeit controversies still exist on the utility of SDF as a biomarker for male infertility. 38,55 Moreover, given the association of SDF and potentially remediable conditions, medical interventions have been explored as a means of improving sperm DNA integrity, with the ultimate goals of enhancing fertility and increasing the likelihood of achieving healthy offspring. ...

... Background Every year more than seven million couples seek treatment for infertility, a disease that affects around 15% of couples worldwide [1]. Unsuccessful clinical pregnancy after 12 months of regular sexual intercourse is considered infertility [2,3]. ...

... Sperm extraction and cryopreservation at the time of vasectomy reversal should be discussed preoperatively. It should be offered as an option for patients who want to avoid a future sperm extraction in the event of persistent oligospermia or azoospermia following reversal [32]. Vasectomy reversal is accomplished by one of two techniques: vasovasostomy (VV) or vasoepididymostomy (VE). ...

... In a recent systematic review and meta--analysis, Kirby et al. concluded that men with varicocele who undergo surgical repair present increased odds of achieving pregnancy and live birth when compared to those who do not (37). In a comment to that article, Hockenberry and Lipshultz added that this finding demonstrates there is essentially a mis-sed opportunity in diagnosing and treating varicocele (38). Indeed, the findings of our study further support the need for a formal urological evaluation and, if needed, intervention, not only with the intent of increasing pregnancy and live birth rates, but in decreasing the potential promutagenic effects of oxidative DNA damage, such as discussed above. ...

... Mean age (years, SD) 58.0 (4.9) 55.0 (6.6) 0. 276 Andrology, 2017, 5, 274-277 with CCH, FSPs reported improvement in their partner's PD symptoms and in female bother by their partner's PD (Goldstein et al., 2015). In this study, FSPs completed the female sexual function index (FSFI) and the Peyronie's disease questionnaire for FSPs (PDQ-FSP), which is adapted from the men's PDQ. ...

... Therefore, testosterone may be a treatment option for most patients with DED (Sullivan et al., 2002;Supalaset et al., 2019). However, testosterone can cause severe systemic side effects and the US FDA issued a warning that testosterone might increase the risks of heart attack and stroke (Seftel, 2015;Ohlander et al., 2016). Further based on a systematic review of clinical studies of applying androgen in the treatment of DED, the administration of testosterone through an ocular drug delivery system (ODDS) can be a favorable option for DED with minimal systemic side effects (Wang & Deng, 2020). ...

... However, there is some conflicting evidence regarding the predictive ability of free testosterone. Ramasamy et al. performed a chart review of over 3000 men attending an outpatient men's health clinic and did not find any association of hypogonadal symptoms with free testosterone among men with near-normal TT [53]. Despite the lack of a clear trend in the associations and predictive ability of total versus free testosterone, evidence from Asian populations does appear to be consistent in identifying that free testosterone, but not total testosterone, has a significant inverse association with age [4, 21, 22] ; this is also consistent with the present study. ...