Lala Bouna Seck’s research while affiliated with Centre Hospitalier National Universitaire de Fann and other places

What is this page?


This page lists works of an author who doesn't have a ResearchGate profile or hasn't added the works to their profile yet. It is automatically generated from public (personal) data to further our legitimate goal of comprehensive and accurate scientific recordkeeping. If you are this author and want this page removed, please let us know.

Publications (97)


Evaluation and Characterization of Executive Function Disorders after Stroke
  • Article

January 2025

·

6 Reads

Open Journal of Psychiatry

El Hadji Makhtar Ba

·

Hilaire Dominique Ewodo Touna

·

·

[...]

·

Aida Sylla




Figure 1. Angio MRI. Thrombosis of the right sinus (white arrow) and the superior sagittal sinus (blue arrow): absence of opacification of the sinus.
Figure 2. Ground glass appearance on chest CT.
Cerebral Venous Thrombosis Post COVID 19 in Neurological Unit of Fann Teaching Hospital
  • Article
  • Full-text available

January 2024

·

71 Reads

Clinical Neurology and Neuroscience

Introduction: The new coronavirus constitutes a public health problem due to its many often fatal complications such as thromboembolic diseases. Upper this infectious state, neurological diseases are reported mainly ischemic stroke and rarely cerebral venous thrombosis. Observation: We report the case of a 76-year-old diabetic, hypertensive patient who was well monitored and who presented neurological manifestations 24 hours after home returning from hospitalization for COVID 19 infection fifteen days before. Major signs were dehydration grade I according to the WHO, confusional syndrom, left pyramidal syndrom of cortical type predominantly on facial and arm and regular tachycardia. The brain imagery revealed a double thrombus in sinus and diagnosis of cerebral thrombosis (CVT) was made. Biological abnormalities were noted, such as neutrophilic hyperleukocytosis and thrombocytopenia. The evolution was favorable with symptomatic treatment and after putting on oral curative dosis anticoagulant. Conclusion: Cases of cerebral venous thrombosis are increasingly reported in the literature, but Cases of CVT in the field COVID 19 remain rare, especially in Africa. Elderly age and vascular risk factors could favorite occurrence of cerebral venous thrombosis in cases of Sars-Cov infection. It is important to think about it in the face of any brain neurological picture given the thrombogenic nature of COVID 19, mainly in geriatric population. However, guidelines must been done for better management of these patients even if outcomes evolution are generally favourable.

Download

The Combination of Mind and Brain Alteration in A Resource-Limited Country: Autism Spectrum Disorders and Epilepsy in A Child Psychiatry Unit in Dakar

December 2023

·

11 Reads

International Journal of Psychiatry Research

Purpose of the study: Autism spectrum disorders (ASD) and epilepsy can coexist in the same person, constituting poor bilateral prognosis factors. This study describes the sociodemographic elements of patients with ASD and studies the clinico-paraclinical aspects of their epilepsy and its evolution in 2003. Patients and Methods: Cross-sectional and descriptive study in Child psychiatry at CHNU Fann, with analysis of the files of all patients followed between January 2004 and September 2018 for ASD with/without epilepsy. We used a standardized survey with several items. Results: Forty -five patients with ASD collected, with an epileptic frequency of 37.8%. The main history was fetal suffering (24.4%) and parental inbreeding (22.2%). Most of the symptoms of ASD were seen before 3 years old (66.6%) and epilepsy started before 5 years (94%). Seizures were generalized (58.8%), mainly tonic-clonic (80%) or focal (35.3%), with a frequency of 2 seizures / day at 1 seizure / week. The EEG showed abnormalities in frontal areas in 60%, and Centro-parietal in 26.6%. Brain imaging and evoked auditory potential were normal respectively in 93.9%, and 87.2%. Management was multimodal for ASD (neuropsychological, psychomotor, speech therapy) and medicated for epilepsy, mainly by monotherapy (82.4%) with Valproate (58.8%), Phenobarbital (17.6). Forty percent of patients were out of school and 55.6% in primary school. Twenty-five patients were self-reliant to moderately independent, mainly the epileptics (60%). The 2023 evaluation of this cohort concerns 60% of patients with epilepsy in complete remission and behavioral and language stability under continuous management. Conclusion: We find a statistic difference by age between epilepsy and ASD with a genetic predisposition related to parental inbreeding and a family history of ASD and epilepsy and to a lesser extent the existence of acute fetal suffering. The contribution of EEG was significant with a predilection of frontal abnormalities whose epileptic treatment appears to improve the impact in children's behavioral disorders.






Citations (28)


... In addition, to assess any case of coinfection all samples were screened for Human Herpesviruses (HHV) including Herpes simplex virus 1 (HSV1), Herpes simplex virus 2 (HSV2), Varicella zoster virus (VZV), Epstein-Barr virus (EBV), Cytomegalovirus (CMV), Human herpesvirus 6 (HHV6) and Human herpesvirus 7 (HHV7) by RT-PCR using the Allplex Meningitis-V1 kit, according to the fabricant's instructions [12]. ...

Reference:

An outbreak of atypical hand, foot and mouth disease associated Coxsackievirus A6 in children from Cape Verde, 2023
Surveillance of Viral Encephalitis in the Context of COVID-19: A One-Year Observational Study among Hospitalized Patients in Dakar, Senegal

... 106 Many types of seizures can be provoked by visual stimuli, including most commonly tonic-clonic seizures in about 80% 9 and the remainder with lower prevalence, including absence seizures, 107 tonic seizures, focal seizures from the temporal lobe, 108 myoclonic absence seizures in patients with Dravet syndrome, 109 myoclonic seizures, 110 and idiopathic photosensitive occipital lobe epilepsy (IPOE). [111][112][113][114] Photic-induced myoclonic seizures may be underrepresented in epidemiological studies, since some people seek medical attention only after having a tonicclonic seizure. IPOE 111,112 is on a continuum between focal and generalized seizures and may present with photosensitive absence, myoclonic or tonic-clonic seizures. ...

Are Sub‐Saharan epileptic people less photosensitive? A Senegalese study of photoparoxysmal response in a reference epilepsy centre

... Nevertheless, etiology maintains similarities with the pattern observed in developed countries, been the sagittal sinus continues also the most affected. Conversely, reports are still limited in other developing countries, particularly in sub-Saharan Africa, where data on incidence, prevalence, and epidemiology remain scarce and significantly differ from those reported elsewhere, establishing infectious etiology as the most common origin [21][22][23][24]. ...

Cerebral venous thrombosis in a sub-saharan African country: A preliminary monocentric study of a 70 case series at the neurology department of Fann teaching hospital in Dakar – Senegal
  • Citing Article
  • October 2020

Revue Neurologique

... Peripheral arterial disease is responsible for ischemia than can lead to ulcers [21]. The high prevalence of arteriopathy in diabetic patient can be explained by the frequency of cardiovascular risk factors (advanced age, alcohol, smoking, arterial hypertension, dyslipidaemia, obesity, sedentary lifestyle) [23,24]. The unfavourable socio-economic level is a factor converging to macrovascular complications of diabetes [4,13]. ...

Evaluation of Podological Risk at Type 2 Diabetics Tracked at the Mark Sankale Diabetes Center in Dakar

Journal of Diabetes Mellitus

... The largest cohort comes from a French study and included 50 patients of families originating from Sub Saharan countries seen in a hospital in Paris over a time period of 36 years [4] . In an African study from Senegal, the manifestations of 16 patients with neuro-Behçet from Dakar were reported [5] . To our knowledge, no previous cases with neuro-Behçet were reported from South Africa. ...

Neuro-Behçet in a Sub-Saharan Africa Country: a Series of Sixteen Patients in Fann Teaching Hospital, Dakar, Senegal
  • Citing Article
  • February 2019

Bulletin de la Société de pathologie exotique

... From December 2000 till 31 st December 2019, 622 cases of NMOSD in Africa. Cases originated from 21 countries: 138 from Morocco [8]- [14], 118 from Algeria [15] [16], 95 from Nigeria [17], 118 from Egypt [18] [19], 29 from South Africa [20], 16 from Senegal [21], and 14 from Tunisia [22] [23], and the remaining from 14 other African countries [21] [24] [25] (Table 1). ...

Neuromyelitis optica spectrum disorders (NMO-SD) in a Sub-Saharan Africa country: A preliminary study of sixteen Senegalese cases
  • Citing Article
  • October 2018

Multiple Sclerosis and Related Disorders

... This receptor-mediated response includes upregulation of genes associated with neurotrophins, neuropeptides, growth factors, extracellular matrix proteins, and fibronectin, all of which play crucial roles in neuroprotection and repair [21]. Furthermore, the combined administration of uridine and cytidine has demonstrated significant efficacy in alleviating pain intensity across various conditions, including diabetic neuropathy, lumbar and cervical pain, as well as trauma-induced compressive injuries [8,22]. Moreover, animal studies also suggest that combining certain B vitamins, such as B1 and B12, may improve neuropathies, enhance motor control, and alleviate both nociceptive and neuropathic pain [8,23]. ...

Efficacy and tolerance of combination of Cytidine 5 ' monophosphate (CMP) and Uridine-5 ' Triphosphate Trisodium (UTP) in patients with diabetic neuropathy: results of a study conducted in Dakar-Senegal
  • Citing Article
  • July 2015

... The scarcity of neurologists and neurophysiologists in the nation could account for this predicament. 35 Approximately 14.2% of patients had experienced an infectious condition before being admitted to the neurology department. Based on the literature, about two-thirds of cases of GBS are preceded by an acute infection occurring within a period of 3-4 weeks. ...

Epidemiology of Acute Polyradiculoneuritis at Fann Department of Neurology Dakar, Senegal

... La inyección de gadolinio a menudo permite delimitar la zona de ruptura de la barrera hematoencefálica. 8,9 Al inicio, la paciente no presentó signos meníngeos, lo que orientó el diagnóstico hacia un ECV. Según algunos estudios, la rigidez de nuca está presente solo en la mitad de ellos, por lo que no debemos considerar este dato como excluyente.¹⁰ ...

Diagnosis Approach and Management of Rhombencephalitis: Literature Review