LISBETH LOAIZA’s research while affiliated with Swine Research Institute (IIP) and other places

A total of 337 individuals from a rural community of Venezuela (Mapurite, Estado Cojedes) were studied. Stoll faecal examination was carried out and the total number of A. lumbricoides was recovered after the treatment of the individuals sampled with Pyrantel pamoate at a dose of 10 mg/Kg body weight in children and 15 mg/Kg in adults. A relationship between the high worm burden condition (individuals excreting more than10000 epg of A. lumbricoides) and the age of the hosts was found. Resulting with the major values of relative risk index (Rr) the 5-9 years old class (Rr= 3.2 t= 3.4). This relationship was not found between high worm burden condition (HWB) and the sex of the hosts. The following individuals have the the highest possibilities to become HWB: with blood group A (Rr=3.05 t= 4.08), with haemoglobine type HbA HbS (Rr=1.86 t= 2.13), individuals with the combinations A HbA HbF (Rr= 3.46 t= 2.31) and A HbA HbS (Rr= 3.11 t= 2.78). It was estimated that the selective treatment of the total HWB detected (72) with an effective product, determined a reduction of 95.4% of the environmental contamination with de eggs and 72.3% of the worm burden

A total of 337 persons (86.8%) were examined by faecal egg count and worm burden by counting expelled parasites following anthelmintic treatment (Oxantel Pyrantel PamoateR) in order to study the prevalence and distribution of Ascaris lumbricoides in the human population of a rural locality from Venezuela. The number of positive diagnosis of A. lumbricoides infection by worm collection was higher than by eggs determination and the degree of infection determined by egg counts resulted well associated with the worm burden (P < 0.001) and so it may used with some confidence. The prevalence and intensity of infection were similar in both sexes. In relation to the age, the highest values for prevalence (P < 0.05), relative risk (P < 0.01) and intensity of infection (P < 0.02) were observed in the 5 to 9 year old children. Within the population, few individual (20.19%) harboured more than 6 roundworms and many of the hosts (38.3%) had only a few (1 to 5 worms) or none worm (41.53%).

A total of 337 individuals from a rural community of Venezuela (Mapurite, Estado Cojedes) was studied. Stoll faecal examination was carried out and the total number of A. lumbricoides was recovered after the treatment of the individuals sampled with Pyrantel pamoate at a dose of 10 mg/kg body weight in children and 15 mg/kg in adults. A relationship between the high worm burden condition (individuals excreting more than 10,000 epg of A. lumbricoides) and the age of the hosts was found. Resulting with the major values of relative risk index (Rr) the 5-9 years old class (Rr = 3.2 t = 3.4). This relationship was not found between high worm burden condition (HWB) and the sex of the hosts. The following individuals have the the highest possibilities to become HWB: with blood group A (Rr = 3.05 t = 4.08), with haemoglobin type HbA HbS (Rr = 1.86 t = 2.13), individuals with the combinations A HbA HbF (Rr = 3.46 t = 2.31) and A HbA HbS (Rr = 3.11 t = 2.78). It was estimated that the selective treatment of the total HWB detected (72) with an effective product, determined a reduction of 95.4% of the environmental contamination with de eggs and 72.3% of the worm burden.