L S Kinabo’s scientific contributions

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Publications (3)


Constituents of Artemisia afra
  • Article

January 1992

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23 Reads

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6 Citations

Fitoterapia

M.H.H. Nkunya

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L.S. Kinabo

Antimalarial Activity of Tanzanian Medicinal Plants 1

September 1990

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67 Reads

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232 Citations

Planta Medica

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M.H.H. Nkunya

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[...]

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V.A.E.B. Kilimali

Tanzanian medicinal plants were extracted and tested for in vitro antimalarial activity, using the multidrug resistant K1 strain of Plasmodium falciparum. Of 49 plants investigated, extracts of three plants were found to have an IC50 between 5-10 micrograms/ml, extracts of 18 other plants showed an IC50 between 10 and 50 micrograms/ml, all others were less active. The three most active extracts were obtained from the tubers of Cyperus rotundus L. (Cyperaceae), the rootbark of Hoslundia opposita Vahl. (Labiatae), and the rootbark of Lantana camara L. (Verbenaceae).


Citations (3)


... Thus, it was tentatively identified as Apigenin 7,4 -dimethyl ether (5-Hydroxy-4 ,7-dimethoxyflavone). This compound was previously identified in A. afra (Nkunya et al., 1992) and A. diffusa (Valant-Vetschera and Wollenweber, 1995) and was identified in the first time in A. campestris. ...

Reference:

Artemisia campestris phenolic compounds have antioxidant and antimicrobial activity
Constituents of Artemisia afra
  • Citing Article
  • January 1992

Fitoterapia

... The antimalarial activity of CRE was investigated using the 4-day suppressive, curative, and prophylactic tests. . α-Cyperone and βselinene autoxidation products derived from C. rotundus are highly promising antimalarial compounds [31]. Furthermore, sesquiterpenoids, such as patchoulenone, caryophyllene α-oxide, 10,12peroxycalamenene, and 4,7-dimethyl-1-tetralone, have been reported to exhibit antimalarial activity against P. falciparum in culture [10]. ...

Antimalarial compounds containing an _,ß-unsaturated carbonyl moiety from Tanzanian medicinal plants.
  • Citing Article