March 2011
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Chinese Journal of Medical Imaging Technology
Objective: To evaluate the effect of shift-and-add (SAA) and filtered back projection (FBP) in digital tomosynthesis on pulmonary nodules detection accuracy. Methods: Fifty patients with small nodules confirmed by chest CT were selected. Digital tomosynthesis images were obtained and processed with SAA and FBP. Three radiologists of different experiences independently reviewed and recorded the results of pulmonary nodules. Totally 102 nodules confirmed with CT were devided into 3 groups: Group of nodules <5 mm, 5-10 mm and >10 mm, respectively, and 2 groups according to the density: Group of solid density nodules and ground-glass density. The results of SAA and FBP were analyzed statistically. Results: SAA detected 52 pulmonary nodules, while FBP found 86 (P<0.001). For nodules with diameter <5 mm and 5-10 mm, FBP displayed more nodules than SAA (P=0.001, 0.005), while no difference was found between two Methods: for >10 mm group (P=0.317). For solid density and ground-glass density nodules, FBP showed more nodules than SAA (both P<0.05). Conclusion: FBP is superior to SAA in detection of nodules with diameter ≤10 mm, small pulmonary nodules with solid density and ground-glass density.