L. Coblentz's research while affiliated with Unity Health System and other places
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Publications (2)
Fourteen dogs with known clinical hypersensitivity to soy and corn were maintained on a limited antigen duck and rice diet until cutaneous manifestations of pruritus were minimal (78 days). Sequential oral challenges with cornstarch, corn and soy were then performed. Subsequently, the dogs were fed a diet containing hydrolysed soy protein and corns...
Hydrolysate diets have been advocated in the management of the food-allergic dog, but little information is available on their performance in dogs with known allergies. Fourteen dogs with known allergies to soy and corn were maintained on a limited antigen diet exclusively for 80 days (Hills d/d Rice and Duck, Hills Pet Nutrition, Topeka, KS). This...
Citations
... Further studies by these two groups reported on allergen-specific IgE and challenge with diets containing a combination of soy, cornstarch and hydrolysed soy. Yet under such controlled conditions, where clinical signs were stimulated with oral challenge there were no statistically significant changes in serum IgE that could predict the clinical outcome (Jackson et al., 2002;Kennis et al., 2002). Furthermore, food allergic dogs with a clinical response to a flavoured oral heartworm prophylactic medication developed clinical signs of pruritus, otitis and colitis, and there were significant peaks in serum allergen-specific IgE to soy, pork and corn, even though the medication only contained pork and soy proteins (Jackson and Hammerberg, 2002b). ...
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... Serological tests involving the measurement of specific IgG and IgE antibodies in serum with western blot have not yet been clinically validated for diagnostics due to its low sensitivity (Mueller and Tsohalis 1998, Foster et al. 2003, Jackson et al. 2003, Martin et al. 2004, Ricci et al. 2010, Zimmer et al. 2011, Bethlehem et al. 2012Favrot et al. 2017). Limited research on serological tests has been performed in cats and, similarly to dogs, it is believed that the concentration of specific antibodies is not reliable in the diagnosis of food allergies. ...
