L. A. Tarskaia’s research while affiliated with Russian Academy of Sciences and other places

... Research among the Yakut, for example, has documented modest physical activity levels, with particularly low levels among those least involved with the subsistence herding economy and those consuming more market foods (Snodgrass et al. 2006b). Furthermore, low activity levels in this population have been linked to several health measures, including chronic inflammation and poor lipid profiles (Wilson et al. 2013). ...

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Health of Indigenous Circumpolar Populations

... More recent research confirmed the systematic elevation of BMR among indigenous Arctic populations, but to a lesser extent. Values ranging from 7% to 19% above the predicted values for males, and from 3% to 17% for females, have been reported by several authors (Katzmarzyk et al., 1994;Galloway et al., 2000;Leonard et al., 2002Leonard et al., , 2005Snodgrass et al., 2005). This metabolic response is shaped by elevating the production of thyroid hormones and sensitivity to them, through short-term acclimatization and genetic adaptations (see Leonard et al., 2005 and references therein). ...

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Shivering in the Pleistocene. Human adaptations to cold exposure in Western Europe from MIS 14 to MIS 11

... These secular trends, however, provide only a partial explanation for variation in metabolic and cardiovascular health among northern communities. Previous work among indigenous circumpolar populations indicates that transitions in metabolic and cardiovascular health are structured by the interaction of lifestyle changes and biological adaptations to local ecological stressors (Cepon et al., 2011;Fumagalli et al., 2015;Leonard et al., 2009;Levy et al., 2012;Snodgrass et al., 2007Snodgrass et al., , 2008. Arctic environments are characterized by extreme seasonal changes in temperature and day length and low overall energy availability. ...

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Lifestyle mediates seasonal changes in metabolic health among the yakut (sakha) of northeastern Siberia

... Brown adipose tissue activates in specific areas of the fat when animals or humans are exposed to the cold [2]. A number of researchers have found indirect evidence of activity of BAT in inhabitants of regions with extremely cold climates [1,6]. However, despite the many indirect signs of activation of brown adipose tissue in adult residents of regions with extremely cold climates, up to date, the fact was not confirmed by histology and morphology verification of BAT. ...

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БУРАЯ ЖИРОВАЯ ТКАНЬ И ЭКСТРЕМАЛЬНО ХОЛОДНЫЙ КЛИМАТ

... However, observations of long-term changes in endocrine levels in individuals living in polar environments have found a decrease in FT3, with no significant changes detected in FT4 and TSH levels. Pathogenic analysis indicates that prolonged exposure to cold significantly raises both the internal production and clearance rates of FT3 [32][33][34]. The study area, Hulunbuir City, situated near the inland arctic region of China, frequently experiences polar cyclones, suggesting that residents exposed to cold conditions may similarly experience fluctuations in FT3 levels. ...

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Prognostic significance of free triiodothyronine levels in alpine region patients undergoing drug-coated balloon therapy for coronary heart disease

... Besides their cultural particularities (Turkic-speakers, cattle/ horse-breeders living among reindeer-breeders, Tungus speakers), previous studies have shown distinctive genetic features. They present a low genetic diversity, possibly due to a population bottleneck or founder effect, and affinities with southern Siberian populations [1][2][3]. ...

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Population genetics of 17 Y-chromosomal STR loci in Yakutia

... In fact, the Yakut population is characterized by a high degree of genetic homogeneity due to geographical isolation and low migration. These factors determined the founder effect and a high frequency of hereditary diseases [7,11,12]. ...

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Mucopolysaccharidosis-Plus Syndrome, a Rapidly Progressive Disease: Favorable Impact of a Very Prolonged Steroid Treatment on the Clinical Course in a Child

... Concerning Yakut history, the Yakut progressive expansion within Yakutia from the area defined by the Lena, Amga, and Aldan rivers (Central Yakutia) gave birth to at least four pockets of Yakut settlements stated on Russian ethno-historic maps (Beffa & Delaby 1994) of the 17 th century. This process may have led to a regional variation as supported by linguistic (Pakendorf 2007) and surname analyses, but also a biological survey based on the polymorphisms of classical markers (Evsyukov et al. 2005). Exploring the genetic variation among these Yakut settlements (Amga-Lena in the Centre and Viljuj in the West) may be relevant to understand the migration process that occurred during Yakut's expansion (Supplementary Fig. 1). ...

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Close genetic relationships in vast territories: Autosomal and X chromosome Alu diversity in Yakuts from Siberia

... In 2009, Flegontova et al. studied various restriction fragment length polymorphisms (RFLP) such as TaqIB, BclI, MboI, TaqID, and TaqI A, in 17 contemporary populations of the East European Plain and Siberia. They reported that the T allele at the rs2234690 (MboI) locus was the most frequent allele in Asian populations (Flegontova et al., 2009). ...

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Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region

... За допомогою прізвищ було проаналізовано структуру популяцій багатьох країн і етнічних груп різних народів світу. Ці дослідження проведені як на індивіду-альному, так і на популяційному рівні [2][3][4][5][6][7][8][9][10][11]. Наші попередні дослідження продемонстрували ефективність використання прізвищ у вивченні українських популяцій. ...

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Population genetic analysis of the Lviv region based on surname data