Kristine Westrom’s research while affiliated with University of Minnesota, Duluth and other places

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Publications (18)


Fig. 7 Mean improvement with 95% confidence intervals
Responder analysis
Multidisciplinary integrative care versus chiropractic care for low back pain: a randomized clinical trial
  • Article
  • Full-text available

December 2022

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180 Reads

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9 Citations

Chiropractic & Manual Therapies

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Craig Schulz

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Roni Evans

Background Low back pain (LBP) is influenced by interrelated biological, psychological, and social factors, however current back pain management is largely dominated by one-size fits all unimodal treatments. Team based models with multiple provider types from complementary professional disciplines is one way of integrating therapies to address patients’ needs more comprehensively. Methods This parallel group randomized clinical trial conducted from May 2007 to August 2010 aimed to evaluate the relative clinical effectiveness of 12 weeks of monodisciplinary chiropractic care (CC), versus multidisciplinary integrative care (IC), for adults with sub-acute and chronic LBP. The primary outcome was pain intensity and secondary outcomes were disability, improvement, medication use, quality of life, satisfaction, frequency of symptoms, missed work or reduced activities days, fear avoidance beliefs, self-efficacy, pain coping strategies and kinesiophobia measured at baseline and 4, 12, 26 and 52 weeks. Linear mixed models were used to analyze outcomes. Results 201 participants were enrolled. The largest reductions in pain intensity occurred at the end of treatment and were 43% for CC and 47% for IC. The primary analysis found IC to be significantly superior to CC over the 1-year period ( P = 0.02). The long-term profile for pain intensity which included data from weeks 4 through 52, showed a significant advantage of 0.5 for IC over CC (95% CI 0.1 to 0.9; P = 0.02; 0 to 10 scale). The short-term profile (weeks 4 to 12) favored IC by 0.4, but was not statistically significant (95% CI − 0.02 to 0.9; P = 0.06). There was also a significant advantage over the long term for IC in some secondary measures (disability, improvement, satisfaction and low back symptom frequency), but not for others (medication use, quality of life, leg symptom frequency, fear avoidance beliefs, self-efficacy, active pain coping, and kinesiophobia). Importantly, no serious adverse events resulted from either of the interventions. Conclusions Participants in the IC group tended to have better outcomes than the CC group, however the magnitude of the group differences was relatively small. Given the resources required to successfully implement multidisciplinary integrative care teams, they may not be worthwhile, compared to monodisciplinary approaches like chiropractic care, for treating LBP. Trial registration NCT00567333.

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Study participant flow chart. tx = treatment; SRE = supervised rehabilitative exercise.
Short‐ or Long‐Term Treatment of Spinal Disability in Older Adults With Manipulation and Exercise

October 2019

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166 Reads

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14 Citations

Objective Back and neck pain are associated with disability and loss of independence in older adults. Whether long‐term management using commonly recommended treatments is superior to shorter‐term treatment is unknown. This randomized clinical trial compared short‐term treatment (12 weeks) versus long‐term management (36 weeks) of back‐ and neck‐related disability in older adults using spinal manipulative therapy (SMT) combined with supervised rehabilitative exercises (SRE). Methods Eligible participants were ages ≥65 years with back and neck disability for ≥12 weeks. Coprimary outcomes were changes in Oswestry Disability Index (ODI) and Neck Disability Index (NDI) scores after 36 weeks. An intent‐to‐treat approach used linear mixed‐model analysis to detect between‐group differences. Secondary analyses included other self‐reported outcomes, adverse events, and objective functional measures. Results A total of 182 participants were randomized. The short‐term and long‐term groups demonstrated significant improvements in back disability (ODI score –3.9 [95% confidence interval (95% CI) –5.8, –2.0] versus ODI score –6.3 [95% CI –8.2, –4.4]) and neck disability (NDI score –7.3 [95% CI –9.1, –5.5] versus NDI score –9.0 [95% CI –10.8, –7.2]) after 36 weeks, with no difference between groups (back ODI score 2.4 [95% CI –0.3, 5.1]; neck NDI score 1.7 [95% CI 0.8, 4.2]). The long‐term management group experienced greater improvement in neck pain at week 36, in self‐efficacy at weeks 36 and 52, and in functional ability, and balance. Conclusion For older adults with chronic back and neck disability, extending management with SMT and SRE from 12 to 36 weeks did not result in any additional important reduction in disability.





Figure 1 of 1
Spinal rehabilitative exercise or manual treatment for the prevention of cervicogenic headache in adults

May 2016

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383 Reads

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5 Citations

Cochrane Database of Systematic Reviews

This is the protocol for a review and there is no abstract. The objectives are as follows: To quantify and compare the short- and long-term effects of manual treatment and spinal rehabilitative exercise for cervicogenic headache, classified according to the International Headache Society's (IHS) diagnostic criteria, with an active or placebo/sham comparison or wait-list control.


Spinal rehabilitative exercise or manual treatment for the prevention of tension-type headache in adults

April 2016

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122 Reads

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5 Citations

Cochrane Database of Systematic Reviews

This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the short- and long-term effects of manual treatment and spinal rehabilitative exercise for the prevention of tension-type headache in adults.


Spinal rehabilitative exercise and manual treatment for the prevention of migraine attacks in adults

August 2015

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203 Reads

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7 Citations

Cochrane Database of Systematic Reviews

This is the protocol for a review and there is no abstract. The objectives are as follows: The objectives of the review are to quantify and compare the short- and long-term effects of manual treatment and spinal rehabilitative exercise for episodic and chronic migraine classified according to the International Headache Societies (IHS) diagnostic criteria.


Figure 1 Model of complementary and integrative healthcare in long-term care.  
table 1 Complementary and Integrative Healthcare (CIH) Treatment Modalities Included in and Excluded From the CIH Model 
table 2 Demographic and Clinical Characteristics a (cont.) 
table 2 Demographic and Clinical Characteristics a 
Complementary and Integrative Healthcare in a Long-term Care Facility: A Pilot Project

January 2015

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248 Reads

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15 Citations

Global Advances in Health and Medicine

Introduction: The world's population is aging quickly, leading to increased challenges of how to care for individuals who can no longer independently care for themselves. With global social and economic pressures leading to declines in family support, increased reliance is being placed on community- and government-based facilities to provide long-term care (LTC) for many of society's older citizens. Complementary and integrative healthcare (CIH) is commonly used by older adults and may offer an opportunity to enhance LTC residents' wellbeing. Little work has been done, however, rigorously examining the safety and effectiveness of CIH for LTC residents. Objective: The goal of this work is to describe a pilot project to develop and evaluate one model of CIH in an LTC facility in the Midwestern United States. Methods: A prospective, mixed-methods pilot project was conducted in two main phases: (1) preparation and (2) implementation and evaluation. The preparation phase entailed assessment, CIH model design and development, and training. A CIH model including acupuncture, chiropractic, and massage therapy, guided by principles of collaborative integration, evidence informed practice, and sustainability, was applied in the implementation and evaluation phase. CIH services were provided for 16 months in the LTC facility. Quantitative data collection included pain, quality of life, and adverse events. Qualitative interviews of LTC residents, their family members, and LTC staff members queried perceptions of CIH services. Results: A total of 46 LTC residents received CIH care, most commonly for musculoskeletal pain (61%). Participants were predominantly female (85%) and over the age of 80 years (67%). The median number of CIH treatments was 13, with a range of 1 to 92. Residents who were able to provide self-report data demonstrated, on average, a 15% decline in pain and a 4% improvement in quality of life. No serious adverse events related to treatment were documented; the most common mild and expected side effect was increased pain (63 reports over 859 treatments). Qualitative interviews revealed most residents, family members and LTC staff members felt CIH services were worthwhile due to perceived benefits including pain relief and enhanced psychological and social wellbeing. Conclusion: This project demonstrated that with extensive attention to preparation, one patient-centered model of CIH in LTC was feasible on several levels. Quantitative and qualitative data suggest that CIH can be safely implemented and might provide relief and enhanced wellbeing for residents. However, some aspects of model delivery and data collection were challenging, resulting in limitations, and should be addressed in future efforts


Figure 1: Participant flow.
Table 2 Descriptions of the interventions
Table 3 Details of exercises in SRE program
Table 4 Data collection schedule
Short term treatment versus long term management of neck and back disability in older adults utilizing spinal manipulative therapy and supervised exercise: A parallel-group randomized clinical trial evaluating relative effectiveness and harms

July 2014

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445 Reads

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13 Citations

Chiropractic & Manual Therapies

Back and neck disability are frequent in older adults resulting in loss of function and independence. Exercise therapy and manual therapy, like spinal manipulative therapy (SMT), have evidence of short and intermediate term effectiveness for spinal disability in the general population and growing evidence in older adults. For older populations experiencing chronic spinal conditions, long term management may be more appropriate to maintain improvement and minimize the impact of future exacerbations. Research is limited comparing short courses of treatment to long term management of spinal disability. The primary aim is to compare the relative effectiveness of 12 weeks versus 36 weeks of SMT and supervised rehabilitative exercise (SRE) in older adults with back and neck disability. Randomized, mixed-methods, comparative effectiveness trial conducted at a university-affiliated research clinic in the Minneapolis/St. Paul, Minnesota metropolitan area. Independently ambulatory community dwelling adults ≥ 65 years of age with back and neck disability of minimum 12 weeks duration (n = 200). 12 weeks SMT + SRE or 36 weeks SMT + SRE. Blocked 1:1 allocation; computer generated scheme, concealed in sequentially numbered, opaque, sealed envelopes. Functional outcome examiners are blinded to treatment allocation; physical nature of the treatments prevents blinding of participants and providers to treatment assignment. 36 weeks post-randomization. Self-report questionnaires administered at 2 baseline visits and 4, 12, 24, 36, 52, and 78 weeks post-randomization. Primary outcomes include back and neck disability, measured by the Oswestry Disability Index and Neck Disability Index. Secondary outcomes include pain, general health status, improvement, self-efficacy, kinesiophobia, satisfaction, and medication use. Functional outcome assessment occurs at baseline and week 37 for hand grip strength, short physical performance battery, and accelerometry. Individual qualitative interviews are conducted when treatment ends. Data on expectations, falls, side effects, and adverse events are systematically collected. Linear mixed-model method for repeated measures to test for between-group differences with baseline values as covariates. Treatments that address the management of spinal disability in older adults may have far reaching implications for patient outcomes, clinical guidelines, and healthcare policy. www.ClinicalTrials.gov; Identifier: NCT01057706.


Citations (12)


... We developed a training and support system to address providers' own capability, opportunity and motivational needs and overcome barriers, to effectively delivering SBSM, based on provider input from previous trials [64][65][66], assessment of providers prior to the feasibility study, and the emerging literature on clinicians' behavioral related needs for supporting patient self-management [45,53]. Provider training and support was designed to facilitate intervention fidelity, and ensure more reproducible processes supporting patient self-management. ...

Reference:

Supported biopsychosocial self-management for back-related leg pain: a randomized feasibility study integrating a whole person perspective
Multidisciplinary integrative care versus chiropractic care for low back pain: a randomized clinical trial

Chiropractic & Manual Therapies

... This retrospective cohort study is a secondary analysis of randomized clinical trial (RCT) data collected on community-dwelling adults ages 65 years or older with chronic spinal pain and disability, and was approved by the Institutional Review Board at Northwestern Health Sciences University [25][26][27]. Recruitment and data collection for the parent RCT was conducted from January 2010 through December 2014. All participants enrolled in the parent RCT received the same study intervention, consisting of primarily high-velocity, low-amplitude chiropractic spinal manipulation plus home exercise instruction for 12 weeks [26]. ...

Short‐ or Long‐Term Treatment of Spinal Disability in Older Adults With Manipulation and Exercise

... Our research group conducted an RCT ( Figure 1) to investigate the relative effectiveness of shortterm (12 weeks) treatment for spinal disability, using a combination of spinal manipulative therapy (SMT) and exercise recommendations, compared to a long-term (36 weeks) management using the same interventions [26,27]. Participants were age 65 and older, community dwelling and independently ambulatory. ...

Short term treatment versus long term management of neck and back disability in older adults utilizing spinal manipulative therapy and supervised exercise: a parallel-group randomized clinical trial evaluating relative effectiveness and harms

Chiropractic & Manual Therapies

... Findings demonstrated that when patients participate in their pain care, they are more satisfied and experience better outcomes. 10 Patient stories were highly regards as the patient introduces how pain interrupts their life. 11 Since patients are credible judges of their pain, patient self-reports serve as the basis for planned intervention by assessing pain intensity, location, and characteristics as well as pain-related interference with activity. ...

OA11.01. Integrative care for the management of low back pain: design of a clinical care pathway
  • Citing Article
  • June 2012

BMC Complementary and Alternative Medicine

... Weiterhin kommen physikalische, kognitive und Entspannungstherapien wie auch Akupunktur, Bioresonanzverfahren, Entgiftungen sowie Therapien aus der traditionellen chinesischen Medizin zur Anwendungmit sehr unterschiedlichen Erfolgen. Der Zustand des Patienten mit Kopfschmerzen erfordert oft eine langwierige und damit kostenintensive medikamentöse Behandlung [1,3,[7][8][9]. Bis heute gibt es für die Kopfschmerzbehandlung keinen "Goldstandard". Chiropraktik wird als Therapie v. a. bei Funktionsstörungen des Bewegungsapparats angewandt. ...

Spinal rehabilitative exercise or manual treatment for the prevention of cervicogenic headache in adults

Cochrane Database of Systematic Reviews

... The guidelines on headaches have recommended different exercise types for different headaches. While studies show the effectiveness of exercises for the cervical region in patients with TTH and CGH (Leininger et al., 2016;Park et al., 2017), the more common recommendation for migraine seems to be aerobic exercise (Barber & Pace, 2020;Fernandez-de-Las-Penas & Cuadrado, 2016;Fernandez-de-Las-Penas et al., 2020;Kuruvilla & Wells, 2019;Lemmens et al., 2019;Luedtke, Allers, et al., 2016). However, recent reviews have stated that cervical musculoskeletal dysfunctions may affect headaches in migraine, and therefore, treatment should include exercise increasing cervical muscle strength and endurance (Carvalho et al., 2020;Côté et al., 2019). ...

Spinal rehabilitative exercise or manual treatment for the prevention of tension-type headache in adults

Cochrane Database of Systematic Reviews

... The prevalence of PIC use varies according to the country and study population. In the United States, approximately 40.0% of the elderly report using these practices, in Iran the prevalence was 75.4% and in Turkey 87.3% of the rural population (Cevik and Tari 2019;Evans et al. 2015;Ghaedi et al. 2017;Martin 2010). In Brazil, the use of these practices has been occurring gradually and slowly. ...

Complementary and Integrative Healthcare in a Long-term Care Facility: A Pilot Project

Global Advances in Health and Medicine

... This retrospective cohort study is a secondary analysis of randomized clinical trial (RCT) data collected on community-dwelling adults ages 65 years or older with chronic spinal pain and disability, and was approved by the Institutional Review Board at Northwestern Health Sciences University [25][26][27]. Recruitment and data collection for the parent RCT was conducted from January 2010 through December 2014. All participants enrolled in the parent RCT received the same study intervention, consisting of primarily high-velocity, low-amplitude chiropractic spinal manipulation plus home exercise instruction for 12 weeks [26]. ...

Short term treatment versus long term management of neck and back disability in older adults utilizing spinal manipulative therapy and supervised exercise: A parallel-group randomized clinical trial evaluating relative effectiveness and harms

Chiropractic & Manual Therapies

... The results of the adequately powered study showed that IHC in people with LBP resulted in statistically significant improvements in pain reduction, perceived global improvement and satisfaction with care compared to those patients receiving chiropractic care alone [43,44]. Quality of life was rated as significantly better in the IHC group compared to the chiropractic group at 52 weeks. ...

P02.129. Individualized chiropractic and integrative care for low back pain: a randomized clinical trial

BMC Complementary and Alternative Medicine

... Finally, some studies were omitted from the review because of insufficient information (eg inadequate reporting of interventions, methods and/or outcomes). 48,49 Although it is possible that the findings of these studies could have shaped the conclusions of this review, attempts to contact authors for additional information were unsuccessful. ...

OA11.04. Psychosocial outcomes from the chiropractic and integrative care low back pain randomized clinical trial

BMC Complementary and Alternative Medicine