Kord Honda’s research while affiliated with Louis Stokes Cleveland VA Medical Center and other places

... Recent studies from various specialties as well as otolaryngology subspecialties have demonstrated declining Medicare physician reimbursement rates. General surgery, 1 neurosurgery, 2 plastic surgery, 3 orthopedic surgery, 4 and dermatology 5,6 have all seen reductions in their respective MPFS procedures as well as downward trends in specific CPTs. No studies to date, however, have evaluated reimbursements for commonly performed procedures within laryngology. ...

Reference:

A Medicare Physician Fee Schedule Analysis of Reimbursement Trends in Laryngology from 2000 to 2021

... The RNAseq data revealed an array of highly enriched myeloid phagocytes in NM-exposed dermis consistent with the murine models (Figs. 2, 3). In human skin a myriad of myeloid cells including neutrophils, conventional dendritic cells (cDC), plasmacytoid DC (pDC), and monocytes were detected (Fig. 6c) 20 . Contrary to the previously held notion of myeloid-driven skin damage after NM exposure, we also detected a dynamic repository of antigen-experienced memory T lymphocytes, particularly effector memory (Tem) CD4 + helper and CD8 + cytotoxic T cells. ...

Reference:

Attenuation of skin injury by a MARCO targeting PLGA nanoparticle

... It has been reported to present in a cellulitis-like manner with a similar constellation of symptoms to our patient, including swelling, erythema and tenderness. 10 In these cases, histopathology would demonstrate infiltration of the dermis or subcutaneous tissues with leukaemic cells. Leukaemia cutis is known to be associated with poor prognosis and should be considered in patients with new skin manifestations with a known underlying haematological malignancy. ...

Reference:

Expanding Subcutaneous Mass on the Scalp of an Immunocompromised Woman

... DM can be challenging to diagnose. Primary tumors can be either amelanotic or melanotic, often resembling other cutaneous malignancies or even benign scar tissue or dermatofibroma [7,8]. Histologically, DM presents as spindle-shaped melanocytes embedded in a dense, fibrous (desmoplastic) collagen matrix, with diminished cellularity relative to other cutaneous melanomas [1]. ...

Reference:

Adjuvant Radiation Therapy in Desmoplastic Melanoma: A Scoping Review

... As a result, the lipoprotein maturation and trafficking pathways have been a focus of novel antibiotic discovery (6). Several compounds have recently been described that target maturation steps in both E. coli and Acinetobacter baumannii (38)(39)(40)(41). Novel inhibitors of lipoprotein trafficking have also been reported that target LolCDE in E. coli (22)(23)(24). ...

Reference:

Genetic analysis reveals a robust and hierarchical recruitment of the LolA chaperone to the LolCDE lipoprotein transporter

... Following the first report of the successful treatment of AAV with RTX, different rare clinical manifestations were reported as having been successfully treated with RTX. Some of the most important rare clinical presentations in GPA patients, which resolved following RTX, include retrobulbar granuloma [78], refractory ophthalmic [126], pachymeningitis [146], the presence of orbital inflammation [122], long-established end-stage renal disease [147], post-kidney-transplantation glomerulonephritis-related AAV [148], pituitary GPA [149], renal mass [150], gastric ulcer [151], pancreatitis [152], ophthalmoplegia [153], pyoderma gangrenosum [154][155][156], prostatitis [157] aortic inflammation [158], intestinal involvement [159], mastitis [160], aortitis [161], gingivitis [162], Isolated Pauci-Immune Pulmonary Capillaritis [163], isolated orbital GPA [164], cranial neuropathy [165], severe necrotizing scleritis [166], genital necrosis and inflammation [167], GPA-associated subcutaneous cheek odule [168], pseudo-tumoral digital nodules [169], hypertrophic pachymeningitis [170,171], acute myocarditis [172], palpable purpura [173], central nervous system vasculitis [174], intra-cranial hypertension [175,176], tracheobronchial stenosis [142], acute aortic valve regurgitation [177], GPA-mimicking meningeal tuberculosis [178], gynecological involvement [179], GPA-mimicking lung malignancies [180], CNS ischemic lesions [181], leukocytoclastic vasculitis-induced penile necrosis [182], stem cell transplantation [183], progressive skull base osteomyelitis [184], severe bilateral sensorineural hearing loss [185], nasal septal abscesses [186], oral and skin ulcer [187], nasal septal abscesses [186], membranous nephropathy [188], ventricular tachycardia [189], and hydralazine-induced AAV [190]. ...

Reference:

The Efficacy and Safety of Rituximab in ANCA-Associated Vasculitis: A Systematic Review

... SS usually presents in individuals in their sixth decade of life [7,10,11]. Occurrence of SS in the pediatric population is rare (with an estimated 5-8% of cases of SS being reported in children [12]), although several cases of pediatric SS have been recently reported in literature [13][14][15][16][17][18][19][20]. In a 2019 French study of 10 pediatric SS patients, the investigators reported a median age of 2.7 years at presentation and a female to male ratio of 2:3. ...

Reference:

New Practical Aspects of Sweet Syndrome

... Miliaria crystallina (MC) is a superficial form of miliaria when sweat glands are obstructed within the stratum corneum [1]. Although there are few adult cases of MC associated with hypernatremia, there is only one neonatal case of MC associated with hypernatremic dehydration (HD) in the literature [3][4][5]. Herein, we report a second neonatal case with MC developed during treatment of severe HD. ...

Reference:

Hipernatremi ve milarya kristalina: nadir bir ilişki

... ICI-induced SLR poses a significant diagnostic challenge [6], with the lungs involved in 60% of cases [7,8]. This can mimic metastasis, as the lungs are the most common site of metastasis for RCC [9]. ...

Reference:

New Mediastinal and Hilar Lymphadenopathy After Adjuvant Pembrolizumab in a Patient With Stage III Clear Cell Renal Cell Carcinoma

... It may be associated with bullous and ulcerative lesions on the palms and soles, with or without cicatricial alopecia and oral involvement. There has also been a report of erosive nail LP with underlying radiographic osteomyelitis [66]. ...

Reference:

Nail lichen planus: A review of clinical presentation, diagnosis and therapy