Kayo Godai's research while affiliated with Osaka City University and other places

Publications (52)

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Background With the aging of the population, it is becoming increasingly important to maintain adequate lipid levels to prevent atherosclerotic cardiovascular diseases (CVD). In older populations, the association between CVD and lipids is controversial. We investigated the association between lipid levels and CVD onset in a community-dwelling older...
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To determine the association between skeletal muscle mass and systolic blood pressure decline over a 5-year period in older adults over 75 years old. Of those who got health checkups at private A clinic from May 2020 to March 2021, 118 subjects for whom data on systolic blood pressure (SBP) levels consequently collected for five years were included...
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It is well known that excessive salt intake is associated with hypertension (HT) and salt intake reduction lowers blood pressure. However, the knowledge of salt intake and blood pressure in the older people is not sufficient. This study aimed to clarify the relationship between salt intake and blood pressure among community-dwelling Japanese older...
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Despite the clear evidence for lowering blood pressure in hypertensive patients, control rates are insufficient, especially among younger adults. The first step in improving control rates is patient behavior to visit an outpatient when hypertension is detected at annual health checkups. The present study aims to explore the demographic and lifestyl...
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This study examined participants’ health-related awareness, changes in health consciousness, and their spillover effects observed through community-wide home blood pressure (BP) monitoring intervention. This study was based on an ongoing community-based intervention study in Nose, Osaka, which was designed to assess the effect of home BP measuremen...
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Few studies have investigated weekly variations in long-term home blood pressure (BP) measurement. The aim of this study was to examine the intra-week variability and the difference in the day of the week on long-term home BP with or without antihypertensive medication. This study was based on an ongoing community-based intervention study in Nose,...
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The purpose of this study was to assess the association between blood pressure (BP) related indicators and physical frailty among the Japanese community-dwelling elderly. The present cross-sectional analysis was based on an ongoing community-based intervention study in Nose, Osaka, which was designed to assess the effect of home BP measurement on p...
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Hypertension, dyslipidemia, and those combinations are very common in older adults. However, the association between cognitive decline and the combination of hypertension and dyslipidemia in older adults is still controversial. Therefore, we investigate the association between cognitive decline and hypertension, dyslipidemia, and their combination...
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We clarify the status of home blood pressure (HBP) measurement during the first 90 days after recommendation of self-measurement and recording among community residents and factors associated with everyday-measurement. The study subjects were 677 participants from the intervention group of NOSE study, a intervention study of HBP measurement in comm...
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Short sleep duration and poor sleep quality in middle age have been reported to affect blood pressure(BP) control. However, the association between sleep duration, sleep quality and BP control is controversial in older adults with hypertension taking antihypertensive drugs. The aim of this study was to investigate this association in 70–80-year-old...
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Background: Factors associated with weight loss in community-dwelling older people have been reported in several studies, but few studies have examined factors associated with weight loss by age groups. The purpose of this study was to clarify factors associated with weight loss by age in community-dwelling older people through a longitudinal study...
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Some studies reported that home blood pressure (HBP) monitoring was conducted by community-dwelling older people themselves, but there have been few studies on HBP including very old populations aged over 90 years old. Thus, the aim of the present study was to clarify the current situation of white-coat and masked phenomena defined by on-site and h...
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Background To answer whether older adults' cognitive function benefits from ICT use, we (1) examined the relationship between ICT use and cognitive decline during the COVID-19 pandemic and (2) explored the potential role of ICT use in mitigating the relationship between loneliness, social isolation, and cognitive decline among community-dwelling ol...
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Background Older adults were expected to experience a decline in physical activities and an increase in social isolation during the COVID-19 pandemic. Methods We investigated the changes in living conditions of 508 older adults (79.70 years ± 0.88) before (from July to December 2019) and during (in August 2020) the pandemic. We compared the mean s...
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Background The relationship between moderate alcohol drinking or other alcohol drinking patterns such as frequency, beverage type, and situation of drinking and cognitive function is not sufficiently clear in older people. The purpose of this study was to investigate the association between alcohol drinking patterns and cognitive function in commun...
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Aim: The aim of this study was to clarify the association between dietary protein intake and decline in the estimated glomerular filtration rate (eGFR) among Japanese older adults. Methods: We used the data of the Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC) study, an ongoing narrow-age range cohort st...
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Aim: To prevent the transmission of the novel coronavirus [COVID-19] and stop its spread, a state of emergency was declared from April to May 2020. People were encouraged to refrain from outings and reduce their contact with people. The purpose of this study was to examine the subjective changes in the amount of activity under COVID-19 crisis among...
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Aim: We examined the effect of "IkiIki Hyakusai Taiso" as way to prevent the physical decline in community-dwelling elderly in Nose Town, Osaka Prefecture. Methods: Participants were community-dwelling elderly who participated in the Preventive Care program "IkiIki Hyakusai Taiso" from October 2015 to June 2019 in Nose Town, Osaka Prefecture, Japan...
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The G allele of FOXO3 gene (Single nucleotide polymorphism – SNP; rs2802292) is strongly associated with human longevity. However, knowledge of the effect of FOXO3 in older populations, men or women, with heart disease is limited. This cross-sectional study in Japan included 1836 older adults in the 70 and 80-year-old groups. DNA samples isolated f...
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Background and Objectives: To deepen the understanding of processes underlying older adults’ behavior during the COVID-19 pandemic, we investigated associations among affective (anxiety about the coronavirus), cognitive (perceived risk of infection and fatality), and behavioral (engagement in preventive behaviors) variables. We also examined how th...
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Background: Physical function is a strong predictor of the adverse outcomes of cardiovascular disease in older populations. However, studies of healthy older people on the prevention of coronary heart disease (CHD) are very limited. Objectives; We prospectively examined the association of walking speed and handgrip strength with CHD in the communit...
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Aim The association between serum uric acid (UA) and atherosclerosis in old people is controversial. Therefore, in this study, we clarified this association by assessing serum UA and common carotid atherosclerosis examined by carotid ultrasound in community‐dwelling older people in their 70s, 80s and 90s in the SONIC study. Methods A cross‐section...
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Despite clear evidence of the benefits of lowering blood pressure among patients with hypertension, the treatment rate remains <40% worldwide. In the present trial, we aimed to investigate the effects of the early promotion of clinic visits among patients with untreated hypertension detected during annual health checkups. This was a worksite-based,...
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Background: Preventing the need for long-term care (LTC) by identifying physical function risk factors are important to decrease the LTC burden. The objective of this study was to investigate whether grip strength and/or walking speed, which are components of the frailty definition, are associated with LTC in community-dwelling older and oldest pe...
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Aim: Heart diseases and social factors are associated with physical frailty, but there are few studies of older people living in the community. Consequently, the aim of this study was to examine the association between heart diseases, social factors and physical frailty in community-dwelling older populations including the oldest-old people. Meth...
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Objective: Physical function is a strong predictor of the adverse outcomes in older populations. We prospectively examined the association of walking speed and handgrip strength with CHD in the community-dwelling older populations. The study cohort in Japan included 1272 older people free from heart disease at the baseline. Physical function was id...
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Despite the clinical usefulness of self-measured home blood pressure (BP), reports on the characteristics of home BP have not been sufficient and have varied due to the measurement conditions in each study. We constructed a database on self-measured home BP, which included five Japanese general populations as subdivided aggregate data that were clu...
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We investigated the association of systolic blood pressure (SBP) level with physical frailty and cognitive function in community-dwelling older Japanese. Using the ‘Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians’ survey as the baseline, we performed a cross-sectional analysis of people aged 70 ± 1 (n = 1000), 80 ± 1 (...
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Aim The incidence of anemia increases with aging, and it is considered to affect mortality through complex pathophysiological outcomes. Although it has been suggested that self‐rated health may also contribute to the prognosis of anemia in older people, the relationship between anemia and self‐rated health is not well understood. This study thus ex...
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Objectives Physical frailty is geriatric syndrome and can increase the risk of adverse outcome in the older population. Heart diseases are associated with physical frailty but a few studies in community-dwelling old population. Therefore the aim of this study was to examine the association between heart diseases, social factors, and physical frailt...
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Background: Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest is still lagging behind. Therefore, the aim of this stud...
Preprint
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Background: Cognitive impairment is a major health concern among older and oldest people.Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest is still lagging behind. Therefore, the aim of this study...
Preprint
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Background: Increasing older people make a cognitive impairment is a major health concerns among older and oldest people. Moreover, the stroke is a relevant contribution for cognitive decline and development of dementia.The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest still lagging behind....
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Aim In recent years, support for coexisting diabetes treatment and work (Ryoritsu Shien) has become increasingly important for employees with diabetes. It is important to identify factors associated with dropout from outpatient visits for diabetes treatment among employees with diabetes to determine appropriate support to prevent dropout. Therefore...
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Although high blood pressure (BP) and BP variability have been reported to be associated with cognitive impairment, few studies have investigated the association between home BP (HBP) and cognitive function in the oldest-old. The aim of this study was to evaluate whether the value of and the day-to-day variability in HBP was associated with cogniti...
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Background Presence of intimate family is considered as one of the related factors of health behaviors. The study aim was to clarify the relationship between the presence of significant others and having a colorectal cancer screening. Methods This study used data of baseline survey of intervention study regarding breast cancer screening at worksit...
Preprint
Background Increasing in the older people and a decline in mortality after stroke, the rate of post-stroke cognitive decline has increased. The relationship between risk factors and post-stroke cognitive decline in dwelling old and oldest people who living in the community especially with asymptomatic stroke have to be elucidated. Therefore, the ai...
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Aim Understanding work-related factors associated with regular exercise in employees could be useful for determining appropriate interventions to prevent the onset and aggravation of diabetes. This study aimed to assess the associations among work-related stress and mental fatigue, and regular exercise in Japanese employees with or without diabetes...
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Despite the wide use of automated devices for the self-measurement of home blood pressure (BP), no evidence is available regarding the accuracy of such devices in oldest-old populations. The aim of this study was to validate the accuracy of the automated oscillometric upper arm-cuff BP-monitoring device according to an international protocol in old...
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The purpose of this study was to investigate the relationship between the frequency of outpatient visits and hypertension control as determined from health insurance records. This 9-year cohort study in Japan was based on 518 participants with hypertension who underwent health checkups in 2004. Participants were aged 35-56 years and none had a hist...
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Background The utility of casual serum triglyceride (TG) as a predictor of type 2 diabetes mellitus (DM) is unclear, especially during the most productive years. Methods Participants were 3271 workers (913 men and 2358 women, age 20–57) without DM at baseline. They underwent consecutive annual medical check-ups for 8 years. The association between...
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The objective of this study was to explore predictors, including social factors, lifestyle factors, and factors relevant to glycemic control and treatment, for mild and severe hypoglycemia in insulin-treated Japanese diabetic patients. This study included 123 insulin-treated diabetic patients who were referred to the diabetes clinic between January...
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Our aim was to assess the impact of increase in homeostasis model assessment of insulin resistance (HOMA-IR) on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion (IIS). This study included 2,209 participants aged 30-69 without diabetes at baseline who underwent comprehensive medical check-ups between April 2...

Citations

... Hypertension is one of the most experienced degenerative diseases that even can cause death for its sufferers (Krinock, Goyal, Goel, & Nadar, 2020). is a silent killer because this disease is asymptomatic and can be noticed mostly when examining other diseases (Tuo et al., 2022). Hypertension can attack both men and women. ...
... Coronavirus disease 2019 (COVID-19) became a global health issue in 2020 and has not been eradicated as of 2023. In a study on ICT use during the pandemic, non-ICT users aged 80 or above and with high loneliness or social isolation scores were more likely to experience cognitive decline [22]. During the COVID-19 pandemic, there is a need to establish strategies to maintain social contact among older adults at high risk of death from infection [23][24][25]. ...
... Some studies suggest that drinking frequency may be a proxy variable for other social factors, and that there is also a possible intermediate factor between drinking frequency and SRMH [8,25]. In the present study, the regression model showed that participants with different drinking frequency habits had differences in the sociodemographic characteristics of their SRMH. ...
... g/kg/day is recommended for patients with CKD stages 3-5 (except for stage 5D) with diabetes to maintain nutritional status and glycaemic control [50,51]. In contrast, in elderly patients with CKD, high protein intake is not associated with reduced kidney function, although the low-protein-intake group reportedly lost a high degree of body weight in one year [52]. High protein intake is reportedly not associated with the risk of developing end-stage kidney disease in elderly patients with CKD [53]. ...
... A total of 269 participants living in Itami and Asago responded to the appropriate questionnaires of this study (response rate: 54.2%). [20]. Among them, the participants who had not been diagnosed with "major sarcopenia" in the previous survey of 2019 (n = 252) were included in the study. ...
... Since 2015, Koriyama City has supported the activities of self-management groups through an exercise called "Iki-Iki Hyakusai Taiso" [9] in collaboration with rehabilitation professionals to assist the self-management groups run by the residents. Participation in this type of exercise improved the physical fitness of the participants and increased their participation in social activities after 1 year [10]. The average age of the participants in this report was 72.6 years. ...
... Associations between FOXO3 rs2802292 and the prevalence of essential hypertension and improved metabolic control in diabetic patients have been shown in previous studies [70,71]. On the other hand, Klinpudtan et al. reported that the longevity-associated G allele of FOXO3 rs2802292 appears to have contrasting associations with heart disease prevalence according to sex in older Japanese people [16]. The FOXO3 protein might play a protective role in chronic kidney disease by preventing mitochondrial damage and ameliorating fibrosis [72,73]. ...
... The perception gap, as well as the fear of coronavirus disease, among different age groups, is the subject of a significant number of theoretical and empirical studies [65][66][67], among which the consensus prevailed that members of the elderly population are one of the most vulnerable risk groups in society [68]. ...
... Heart disease data were obtained from the questionnaire, which asked about medical diagnoses that the participant had received from a doctor [16]. A current or previous diagnosis of heart disease was classified as either coronary heart disease or other heart disease (e.g., heart failure, aortic aneurysm, carotid arteries) based on the classifications used in previous research [17]. ...
... AIP has been shown to be a strong predictor of atherosclerosis and coronary heart disease risk (1,2), which reflects the relationship between non-atherogenic and atherogenic lipoprotein level and correlates with lipoprotein particle size (2,3). Uric acid is one of the leading indicators of cardiovascular diseases (4). High uric acid levels are considered an independent risk factor for atherosclerosis and cardiovascular events (5). ...