Kathleen Vanheusden's research while affiliated with Erasmus MC and other places

Publications (16)

Article
Some women at risk for hereditary breast cancer are at increased risk of psychological distress. In order to tailor support for individual women, the availability of a tool enabling the identification of psychologically vulnerable women at an early stage is warranted. The objectives of this study were (1) to explore long-term psychological distress...
Article
The objectives of the present study were to (1) evaluate whether social and personal resources were independently related to psychological distress and (2) examine the interrelationships of social and personal resources in women at risk for hereditary breast cancer. General and breast cancer specific distress, family communication regarding heredit...
Article
Full-text available
Hereditary breast cancer has a profound impact on individual family members and on their mutual communication and interactions. The way at-risk women cope with the threat of hereditary breast cancer may depend on the quality of family communication about hereditary breast cancer and on the perceived social support from family and friends. Objective...
Article
To explore the course of psychological distress and body image at long-term follow-up (6-9 years) after prophylactic mastectomy and breast reconstruction (PM/BR) in women at risk for hereditary breast cancer, and to identify pre-PM risk factors for poor body image on the long-term. Psychological distress (general and breast cancer specific) and bod...
Article
Clarification of the role of several aspects of self-concept regarding psychological distress in women at risk of hereditary breast cancer will help to target counselling and psychosocial interventions more appropriately. In this study, we aimed (1) to examine the role of general self-esteem and specific aspects of self-concept (i.e. stigma, vulner...
Article
Full-text available
Peutz-Jeghers syndrome (PJS) is a hereditary disorder caused by LKB1 gene mutations, and is associated with considerable morbidity and decreased life expectancy. This study was conducted to assess the attitude of PJS patients towards family planning, prenatal diagnosis (PND) and pregnancy termination, and pre-implantation genetic diagnosis (PGD). I...
Article
Background Partners are an importance source of support for women at risk for hereditary breast cancer. The impact of regular breast cancer surveillance in at-risk women on psychological distress in the partners of these women is unknown. This study aimed to (1) examine the levels and courses of psychological distress of partners and high-risk wome...
Article
Little is known about psychological distress and quality of life (QoL) in patients with Peutz-Jeghers syndrome (PJS), a rare hereditary disorder. We aimed to assess QoL and psychological distress in PJS patients compared to the general population, and to evaluate determinants of QoL and psychological distress in a cross-sectional study. PJS patient...
Article
Familiaire adenomateuze polyposis coli (FAP) is een erfelijke aandoening die gepaard gaat met darmpoliepen en kanker en die wordt veroorzaakt door kiembaanmutaties in het APC-gen. Mutatiedragers ontwikkelen honderden tot duizenden poliepen in de dikke darm, waarbij preventieve darmverwijdering op jongvolwassen leeftijd veelal noodzakelijk is. Echte...
Article
Familial adenomatous polyposis coli (FAP) is an inherited predisposition to develop hundreds to thousands adenomatous colorectal polyps leading to colorectal cancer, and is caused by germline mutations in the APC-gene. Polyps generally develop in childhood and are often asymptomatic or give aspecific symptoms. However, other extra-intestinal manife...
Article
Psychotic disorders are more common in people from ethnic minorities. If psychosis exists as a continuous phenotype, ethnic disparities in psychotic disorder will be accompanied by similar ethnic disparities in the rate of psychotic symptoms. This study examined ethnic disparities in self-reported hallucinations in a population sample of young adul...
Article
Mental health problems in young adults are frequent and impairing, but are often left untreated. This study among young adults with self-perceived mental health problems examines beliefs about mental health problems (i.e. their cause, consequences, timeline, and controllability) and help-seeking behaviour. A cross-sectional population survey (n = 2...
Article
Mental health problems often emerge in young adulthood. Although effective treatments are available, young adults are unlikely to seek professional help. This study examined barriers-to-care in young adults with serious internalizing or externalizing problems. Population-based study among 2258 19-32-year olds in the south-west region of the Netherl...
Article
Mental health problems are highly prevalent in young adults. Despite possibilities for effective treatment, only about one-third of young adults with mental health problems seek professional help. Little knowledge exists of which groups of young adults are underusing mental health services and for what reasons. The present study examined socio-demo...
Article
This study examined levels of internalizing and externalizing problems over the full spectrum of alcohol consumption in young adults and identified whether social factors account for the associations of alcohol consumption with internalizing and externalizing problems. This study was a cross-sectional random sample study among 2,258 young adult men...
Article
Only up to one-third of young adults with a mental disorder seek professional help. The reasons for this low help-seeking rate are largely unclear. The first aim of this thesis is to explain why young adults are unlikely to seek professional help when facing mental health problems. The second aim is to provide insight into problem behaviours that t...

Citations

... Research suggests there is a relationship between self-reported depressive symptoms and school dropout among students (Quiroga, Janosz, Bisset & Morin, 2013). It is critical that individuals demonstrating mental health problems during this phase of life, such as depression or depressive symptoms, seek appropriate help early (Vanheusden, 2008). However, individuals aged 18-24 years are less likely to make use of mental health services than those in other age groups. ...
... The impact of BRCA1/2 diagnoses and associated treatment/surveillance among medically underserved groups, such as racial/ethnic, sexual, and impoverished minorities, has outlined that breast and ovarian risk disparities exist [19]. Past literature has found that non-Hispanic white (NHW) women not living in poverty are more likely to undergo testing for BRCA1/2 mutations because these groups have access to quality healthcare and cost-related resources that other groups do not have [20]. ...
... Moreover, perceived availability of social support was positively associated with health-related quality of life in individuals undergoing genetic counselling for both HBOC and LS [31]. In addition, perceiving others as supportive was found to be associated with more open communication within the family and higher self-esteem which were, in turn, associated with less cancer-risk related distress in women at risk of HBOC [32]. Collectively, these findings point to a clear association of social support with cancer related distress, however the underlying mechanisms by which this association occurs have been less studied. ...
... However, it is now increasingly used for adult-onset conditions, including hereditary cancer predisposition syndromes such as hereditary breast and ovarian cancer syndrome (i.e., germline BRCA1/BRCA2 variants) and Lynch syndrome (previously known as Hereditary Non-Polyposis Colorectal Cancer/HNPCC due to germline MLH1, MSH2, MSH6, PMS2, or EPCAM variants) [9]. Prior studies have investigated attitudes of cancer predisposition variant carriers towards the use of IVF-PGT [10][11][12][13][14][15][16][17][18][19][20][21]. In these investigations, a generally favorable attitude towards PGT, consisting of a desire to learn about and willingness to consider PGT, was identified among respondents. ...
... Findings also show that the main drivers of perceived social support are the significant others and the family. These results reinforce previous research [51,52,53] that suggests that the family is the main source of emotional and informational support and that communal coping processes within the family occur to facilitate adaptation to hereditary cancer syndromes. Moreover, results showed that perceived social support is atemporally associated with cancer-risk distress through expressive suppression. ...
... Because it is the most severe complication and leading cause of death, PJS-related cancer has always been a major concern for patients and affected families. There have been some assessments of the mental health of patients with PJS, showing that stress surrounding the development of a malignancy was associated with a large psychological burden (7,8), including our previous report of Chinese PJS patients who showed signs of stress when developing cancer (mean ± SD = 17.83 ± 5.83) using the Cancer Worry Scale (9). PJS patients were extremely worried and afraid of PJS-related cancers, because this disease had a significantly higher cancer risk compared with the general population and the relative risk for any cancer was reported to vary from 9.9−18 (10). ...
... Although a previous study attempted to explore the efficacy of MBSR program on psychological distress from three perspectives, including mindfulness skills, self-compassion, and rumination [42], J o u r n a l P r e -p r o o f the exact psychosocial mechanisms by which MBSR program alleviates psychological distress remain unclear. Previous studies have revealed that several psychosocial factors in cancer patients are associated with psychological distress, such as social support [46], perceived stigma [47], perceived stress [48], intrusive thoughts [49], symptom burden [49], type D personality [49], coping style [50], selfesteem [51], mindfulness [52,53], and illness perception [54,55]. In addition, our previous studies explicitly investigated the roles of social support, perceived stigma, perceived stress, coping styles, self-esteem, mindfulness, and illness perception in the development of psychological distress in lung cancer patients [15,[56][57][58]. ...
... Illness representation, which is the beliefs and perceptions about an illness, may influence people's care-seeking behaviors (10,11). According to the Common Sense Model of Self-Regulation, a health threat stimulus, can activate two sets of illness representations: cognitive representations for regulating the objective health threat and emotional representations for appraising and managing their emotions (12). ...
... Other studies have shown that hallucinations were more common in immigrants than in natives. However, the association between ethnicity and hallucinations diminished after adjustment for social adversity, which supports the view that adverse social experiences contribute to the higher rates of psychosis among migrants [39]. ...